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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
human p300
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "human p300" in MCE Product Catalog:
Cat. No.: HY-RS04405
Target:
Research Areas:
EP300 Human Pre-designed siRNA Set A contains three designed siRNAs for EP300 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P702892
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Ep300; Histone Crotonyltransferase p300; Ep300 Lysine Acetyltransferase; Histone Butyryltransferase p300; p300; Protein Lactyltransferas p300; Histone Acetyltransferase p300; E1A-Associated Protein p300; E1A Binding Protein p300; p300 HAT; KAT3B; E1A-Bind
Species:
Human
Source:
E. coli
Cat. No.: HY-P7S0575
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Ep300; Histone Crotonyltransferase p300; Ep300 Lysine Acetyltransferase; Histone Butyryltransferase p300; p300; Protein Lactyltransferas p300; Histone Acetyltransferase p300; E1A-Associated Protein p300; E1A Binding Protein p300; p300 HAT; KAT3B; E1A-Binding Protein, 300kD; Protein 2-Hydroxyisobutyryltransferase p300; Histone Acetyltransferase; Protein Isonicotinyltransferase p300; MKHK2; Protein Propionyltransferase p300; RSTS2
Species:
Human
Source:
E. coli
Cat. No.: HY-181669
CAS No.: 3034595-62-2
Target:
Research Areas:
P300-IN-6 is an orally active histone acetyltransferase p300 HAT domain inhibitor with human IC50 values of 7 nM. P300-IN-6 suppresses c-Myc expression, decreases H3K18ac and H3K27ac levels, and inhibits cancer cell proliferation.P300-IN-6 suppresses tumor growth in xenograft mouse models.P300-IN-6 can be used for the research of multiple myeloma .
Cat. No.: HY-181957
CAS No.: 3082090-83-0
Research Areas:
KB528 is a p300/CBP histone acetyltransferase (KAT) inhibitor with low nM IC50 values against human p300 and CBP, and exhibits selectivity over other KAT family members. KB528 modulates the IRF4 transcriptional network, downregulates the expression of IRF4, MYC, CAV2 and IGLL5, and reduces the protein level of IKZF3. KB528 potently induces apoptosis in multiple myeloma cells. KB528 is applicable to research related to multiple myeloma .
Cat. No.: HY-114510
CAS No.: 1020399-52-3
PRMT/HKMT-IN-1 is an epigenetic multi-target protein arginine methyltransferases (PRMTs) and histone lysine methyltransferases (HKMTs) inhibitor. PRMT/HKMT-IN-1 inhibits Aspergillus nidulans RmtA with an IC50 of 29 μM. PRMT/HKMT-IN-1 inhibits human PRMT1, p300/CBP HAT, CARM1, SET7, SIRT1 and SIRT2. PRMT/HKMT-IN-1 inhibits methylation of histone H3K4, H4R3, and H3R17 residues. CBP/p300-IN-23 induces apoptosis, arrests cell cycle in S phase, and triggers granulocytic differentiation in leukemia cells. PRMT/HKMT-IN-1 can be used for the research of leukemia .
Cat. No.: HY-P702904
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KAT2B; K(Lysine) Acetyltransferase 2B; Prev. PCAF; Histone Acetylase PCAF; P/CAF; GCN5L; p300/CBP-Associated Factor; GCN5; Spermidine Acetyltransferase KAT2B; CREBBP-Associated Factor; Histone Acetyltransferase KAT2B; CAF; Lysine Acetyltransferase 2B; His
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
