330 Results for "

human platelet

" in MedChemExpress (MCE) Product Catalog:
Products (330)

330 Results for "human platelet" in MCE Product Catalog:

30
PDGF-BB Protein, Human
PDGF-BB Protein, Human
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30 Publications Verification
Cat. No.: HY-P7055
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDGFB; platelet-Derived Growth Factor 2; Prev. SIS; PDGF Subunit B; platelet-Derived Growth Factor Beta Polypeptide; PDGF2; platelet-Derived Growth Factor Subunit B; platelet-Derived Growth Factor, Beta Polypeptide (Oncogene SIS); platelet-Derived Growth
Species:  
Human
Source:  
E. coli
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29
Calpeptin
Calpeptin
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29 Cited Publications
Cat. No.: HY-100223
CAS No.: 117591-20-5
Purity:  ≥98.0%
Target:  

Cathepsin Proteasome Apoptosis

Research Areas:  

Inflammation/Immunology

Calpeptin is a potent, cell penetrating calpain inhibitor, with an ID50 of 40 nM for Calpain I in human platelets . Calpeptin is also an inhibitor of cathepsin K .
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12
Adenosine 5'-diphosphate
Adenosine 5'-diphosphate
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12 Cited Publications
Cat. No.: HY-W010918
CAS No.: 58-64-0
Synonyms: Adenosine diphosphate; ADP
Category:  

Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Endogenous Metabolite

Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors.
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11
Adenosine 5'-diphosphate sodium salt
Adenosine 5'-diphosphate sodium salt
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11 Cited Publications
Cat. No.: HY-W010791
CAS No.: 20398-34-9
Target:  

Endogenous Metabolite

Research Areas:  

Others

Adenosine 5'-diphosphate sodium salt is a nucleoside diphosphate and the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate sodium salt induces human platelet aggregation and inhibits stimulated adenylate cyclase through its action on P2T-purinergic receptors .
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11
Spermine
Spermine
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11 Cited Publications
Cat. No.: HY-B1777
CAS No.: 71-44-3
Synonyms: NSC 268508; Neuridine
Category:  

Human Gut Microbiota Metabolites Natural Products Microorganisms Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Bacterial Reactive Oxygen Species (ROS) DNA/RNA Synthesis

Spermine is a natural antioxidant and anti-inflammatory agent. Spermine is known to inhibit some bacterial cultures, especially strains of Staphylococcus aureus. Spermine can reversibly inhibits DNA synthetic response, mixed lymphocyte response and the induction of cytolytic lymphocyte response in primary cultures of murine spleen cells. Spermine is a polyamine nitric oxide donor that can provide nitric oxide to platelets and inhibit platelet activation to a certain extent concentration-dependently. Spermine occurs in mammalian tissues, plants, bacteria, ribosomes and bacteriophage. Spermine inhibits primary human embryo lung fibroblasts in vitro .
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11
Spermine tetrahydrochloride
Spermine tetrahydrochloride
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11 Cited Publications
Cat. No.: HY-B1777A
CAS No.: 306-67-2
Category:  

Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Bacterial Reactive Oxygen Species (ROS) DNA/RNA Synthesis

Spermine tetrahydrochloride is a polyamine nitric oxide donor that can provide nitric oxide to platelets and inhibit platelet activation to a certain extent concentration-dependently. Spermine tetrahydrochloride occurs in mammalian tissues, plants, bacteria, ribosomes and bacteriophage. Spermine tetrahydrochloride inhibits primary human embryo lung fibroblasts in vitro. Spermine is a natural antioxidant and anti-inflammatory agent. Spermine is known to inhibit some bacterial cultures, especially strains of Staphylococcus aureus. Spermine induces neurotoxicity in the striarum dose-dependently. Spermine can reversibly inhibits DNA synthetic response, mixed lymphocyte response and the induction of cytolytic lymphocyte response in primary cultures of murine spleen cells .
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9
Human α-Thrombin (Lyophilized)
Human α-Thrombin (Lyophilized)
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9 Cited Publications
Cat. No.: HY-114164H
CAS No.: 9002-04-4
Synonyms: EC 3.4.21.5 (Lyophilized); human Alpha Thrombin (Lyophilized)
Target:  

Ser/Thr Protease Thrombin Protease Activated Receptor (PAR) Factor Xa

Research Areas:  

Cardiovascular Disease

Human α-Thrombin (EC 3.4.21.5; Human Alpha Thrombin) (Lyophilized) is a terminal serine protease in the coagulation cascade, as well as a potent physiological platelet agonist and fibrin-generating enzyme in vivo. Human α-Thrombin catalyzes the conversion of fibrinogen to fibrin for blood clot formation, and activates platelet aggregation by cleaving the protease-activated receptors PAR1 (major) (Kd = 1 nM) and PAR4 (minor) on the platelet surface to expose tethered ligands. Human α-Thrombin also amplifies coagulation via positive feedback by activating coagulation factors V, VIII, XI (FV/FVIII/FXI), and switches to activate protein C to exert anticoagulant effects after binding to thrombomodulin .
This product is in a freeze-dried form.
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8
Compound 48/80 trihydrochloride
Compound 48/80 trihydrochloride
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8 Cited Publications
Cat. No.: HY-130592
CAS No.: 848035-21-2
Purity:  99.95%
Synonyms: C48/80 trihydrochloride
Target:  

Phospholipase

Research Areas:  

Neurological Disease

Compound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of condensation products of N-methyl-p-methoxyphenethylamine with formaldehyde. Compound 48/80 trihydrochloride is also a histamine releaser and a mast cell degranulator. Compound 48/80 inhibits phosphatidylinositol-specific phospholipase C activity from human platelets .
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6
TRAP-6
TRAP-6
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6 Cited Publications
Cat. No.: HY-P0078
CAS No.: 141136-83-6
Synonyms: PAR-1 agonist peptide; Thrombin Receptor Activator Peptide 6
Target:  

Protease Activated Receptor (PAR)

Research Areas:  

Inflammation/Immunology

TRAP-6 (PAR-1 agonist peptide), a peptide fragment, is a selective protease activating receptor 1 (PAR1) agonist. TRAP-6 activates human platelets via the thrombin receptor. TRAP-6 shows no activity at PAR4 .
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5
Cinchonine
Cinchonine
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5 Cited Publications
Cat. No.: HY-Y0152
CAS No.: 118-10-5
Synonyms: (8R,9S)-Cinchonine; LA40221
Category:  

Alkaloids Piperidine Alkaloids 500 - Internal Server Error | MedChemExpress

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