62 Results for "

human urine

" in MedChemExpress (MCE) Product Catalog:
Products (62)

62 Results for "human urine" in MCE Product Catalog:

12
12 Publications Verification
Cat. No.: HY-153169
CAS No.: 2754428-18-5
Purity:  99.30%
Synonyms: 6PPD-Quinone
6PPD-Q (6PPD-Quinone) is an environmental pollutant that can be detected in human urine and is widely present in the environment. 6PPD-Q targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1, with CNR2 exhibiting the highest binding affinity, potentially acting as a CNR2 receptor agonist to activate cannabinoid receptors. 6PPD-Q induces intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolysis metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation. 6PPD-Q is applicable in research on environmental toxicology, neurodegenerative diseases, and inflammation-related disorders .
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5
5 Cited Publications
Cat. No.: HY-P72974
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DNASE1; DRNI; Prev. DNL1; Alternative Protein DNASE1; Deoxyribonuclease I; DNase I, Lysosomal; Deoxyribonuclease-1; DNase I; Dornase Alfa; DNAse1; Deoxyribonuclease 1; human urine Deoxyribonuclease I
Species:  
Human
Source:  
HEK293
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2
2 Cited Publications
Cat. No.: HY-13679
CAS No.: 19767-45-4
Purity:  99.78%
Synonyms: Mesnum
Research Areas:  

Inflammation/Immunology

Sodium 2-mercaptoethanesulfonate (Mesnum) is a thiol-containing urinary tract protective agent and aldehyde scavenger that detoxifies acrolein via its thiol group to form an inert thioether excreted in urine, and competitively inhibits human myeloperoxidase, thereby mitigating Cyclophosphamide (HY-17420)-induced cytogenetic damage. Sodium 2-mercaptoethanesulfonate can be used for research on hemorrhagic cystitis .
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2
2 Cited Publications
Cat. No.: HY-W002105
CAS No.: 3238-40-2
2,5-Furandicarboxylic acid is an endogenous metabolite that can be detected in human urine. 2,5-Furandicarboxylic acid serves as an environmentally friendly substitute for terephthalic acid in the production of polyesters. 2,5-Furandicarboxylic acid can be used as the raw material for various chemical intermediates to synthesize polymers, polyurethanes, thermosetting resins, and plasticizers .
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1
1 Cited Publications
Cat. No.: HY-N9457
CAS No.: 60696-62-0
Norcholic acid is a normal minorbile C23 bile acid having four side chain and exsits in human urine and meconium. Norcholic acid can become prominent under certain pathological conditions. Norcholic acid is efficiently absorbed from intestine and quickly excreted into the bile but not into urine .
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1
1 Cited Publications
Cat. No.: HY-113095
CAS No.: 178167-75-4
Purity:  98.30%
γ-CEHC is a γ-tocopherol (HY-N7148) metabolite. γ-CEHC is mainly excreted into the urine rather than into the bile. γ-CEHC is present in conjugated form in human urine, mainly as glucuronide .
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1
1 Cited Publications
Cat. No.: HY-128129
CAS No.: 892742-76-6
Purity:  99.68%
Target:  

Urea Transporter

Research Areas:  

Metabolic Disease

UT-B-IN-1 (UTBINH-14) is a reversible, competitive and selective urea transporter-B (UT-B) inhibitor with IC50 values of 10 and 25 nM for human and mouse UT-B, respectively. UT-B-IN-1 shows low toxicity and high selectivity for UT-B over UT-A isoforms. UT-B-IN-1 increases urine output and reduces urine osmolality of mice. UT-B-IN-1 can be used for diuretic mechanism research .
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1
1 Cited Publications
Cat. No.: HY-P2281A
Synonyms: Atrial natriuretic peptide (1-28) TFA
Atrial natriuretic factor (1-28) (human, porcine) TFA exhibits blood pressure lowering activity by increasing sodium and urine excretion. Atrial natriuretic factor (1-28) (human, porcine) TFA inhibits the release of pituitary adrenocorticotropic hormone (ACTH) and beta-endorphin through inhibition of pro-opiomelanocortin (POMC) expression. Atrial natriuretic factor (1-28) (human, porcine) TFA increases cGMP levels in RMIC cells with an IC50 of 1.2 nM .
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Cat. No.: HY-77641
CAS No.: 16534-24-0
Cinnamoylglycine is a human urinary metabolite and PPG analog. Cinnamoylglycine is a conjugate of cinnamic acid and glycine. Cinnamoylglycine is used as a urine marker. Cinnamoylglycine can be used in adipogenic differentiation studies .
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Cat. No.: HY-151027S
CAS No.: 2687960-87-6
Purity:  95.1%
Synonyms: ADT-G-d4
Androsterone glucuronide-d4 (ADT-G-d4) is the deuterated-labeled Androsterone glucuronide (HY-113104). Androsterone glucuronide (ADT-G) is a major phase II glucuronidated metabolite of androgens (such as testosterone and dihydrotestosterone) in the human body and can be found in urine. Androsterone glucuronide levels can reflect the absorption and hepatic metabolism of testosterone. Androsterone glucuronide can be used in research on hirsutism, polycystic ovary syndrome, and moderate acne .
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Cat. No.: HY-N13356
CAS No.: 5652-48-2
Synonyms: gamma-Glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr
L-gamma-Glutamyl-L-threonine (gamma-Glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr) is a dipeptide obtained through the formal condensation of the L-glutamic acid side chain carboxyl group and the L-threonine amino group. L-gamma-Glutamyl-L-threonine is present in high concentrations in human urine and exhibits antibacterial activity against Gram-negative bacterial. L-gamma-Glutamyl-L-threonine is also a flavor compound. Gamma-Glutamylthreonine is a metabolite catalyzed by γ-glutamyl transpeptidase and is associated with immune regulation. Gamma-Glutamylthreonine can be used in research on inflammation and bacterial infections .
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Cat. No.: HY-165151
CAS No.: 28925-89-5
Synonyms: Urochrome hydrochloride
Target:  

Endogenous Metabolite

Research Areas:  

Others

Urobilin hydrochloride is the metabolite of Hemoglobin (HY-P2995), that can be excreted through urine and feces in many mammals. Urobilin hydrochloride can be used as an indicator of human waste pollution .
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Cat. No.: HY-W017523
CAS No.: 1501-27-5
5-Methoxy-5-oxopentanoic acid is a natural metabolite in human urine. 5-Methoxy-5-oxopentanoic acid is a derivative of Glutaric acid (HY-W008820) and a chiral building block .
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Cat. No.: HY-129912A
CAS No.: 178244-42-3
Purity:  ≥98.0%
N1,N8-Diacetylspermidine hydrochloride is a polyamines in the human urine . N1,N8-Diacetylspermidine hydrochloride is useful as prognostic indicators after treatment and during follow-up examination of cancer patients .
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Cat. No.: HY-107989
CAS No.: 97048-13-0
Target:  

Antibiotic

Research Areas:  

Endocrinology

Urofollitropin is a protein extract of human menopausal urine. Urofollitropin has the function of promoting follicle development and maturation, but contains very small amounts of urinary proteins .
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Cat. No.: HY-113406
CAS No.: 6418-78-6
Synonyms: DL-Hexanoylcarnitine
(±)-Hexanoylcarnitine exists in human urine and plasma. (±)-Hexanoylcarnitine can be used as a plasma detection indicator in patients with methylmalonic aciduria, propionic acidemia, and medium-chain acyl-CoA dehydrogenase deficiency .
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Cat. No.: HY-W008343
CAS No.: 874-14-6
1,3-Dimethyluracil is a pyridine derivative of Uracil (HY-I0960). 1,3-Dimethyluracil is occasionally found in human urine. 1,3-Dimethyluracil exhibits inhibitory activity against hCA I and hCA II, with Ki values of 316.2 μM and 166.4 μM, respectively. 1,3-Dimethyluracil can be used for Parkinson's disease research .
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Cat. No.: HY-W012168
CAS No.: 1205-30-7
Target:  

Carbonic Anhydrase

Research Areas:  

Metabolic Disease

4-Chloro-3-sulfamoylbenzoic acid is a weak inhibitor of human carbonic anhydrase isoforms hCA I, hCA II, hCA IV, and hCA IX, and a synthesis intermediate for carbonic anhydrase inhibitors. 4-Chloro-3-sulfamoylbenzoic acid is the major metabolite of tripamide detected in tissues, urine, and feces of rats and rabbits following Tripamide (HY-106570) administration. 4-Chloro-3-sulfamoylbenzoic acid can be used for the study of carbonic anhydrase inhibition and species differences in drug metabolism .
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Cat. No.: HY-158161
CAS No.: 3032920-98-9
Research Areas:  

Metabolic Disease

JN-170 is a potent and highly selective inhibitor and transport corrector of human SLC6A19 (IC50=47 nM). Furthermore, at a concentration of 35 μM, JN-170 exhibits no activity against SLC1A5, SLC7A5, or SLC6A8. JN-170 is applicable to research on phenylketonuria (PKU) and hyperphenylalaninemia. JN-170 is also suitable for studies related to various metabolic disorders, including tyrosinemia, maple syrup urine disease, urea cycle disorders, and hyperammonemia .
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Cat. No.: HY-P5694
Research Areas:  

Infection

Human α-defensin 5 is an orally active antimicrobial peptide with diverse biological activities including antibacterial, antiviral, and antiparasitic effects. Human α-defensin 5 kills UPEC, inhibits bacterial biofilm formation, and disrupts bacterial outer membrane integrity. Human α-defensin 5 is hijacked by Shigella flexneri, enhancing Shigella adhesion, aggregation, and invasion of host epithelial cells, and aggravating histopathological damage in corneal and colonic tissues as well as fever. Human α-defensin 5 inhibits LPS-induced pro-inflammatory cytokine production and NF-κB signaling pathway activation, upregulates the tight junction proteins ZO-1 and occludin, and maintains intestinal epithelial barrier integrity. Human α-defensin 5 inhibits various non-enveloped viruses and exhibits killing activity against Toxoplasma gondii tachyzoites. Human α-defensin 5 reduces UPEC bacterial load in the bladder and urine and alleviates inflammatory damage in a rat catheter-associated urinary tract infection model. Human α-defensin 5 can be used in research related to bacterial infections, viral infections, parasitic infections, and inflammatory bowel disease .
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