27 Results for "

hydroxamic acid

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "hydroxamic acid" in MCE Product Catalog:

179
Vorinostat
Vorinostat
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179 Publications Verification
Cat. No.: HY-10221
CAS No.: 149647-78-9
Purity:  99.58%
Synonyms: SAHA; Suberoylanilide hydroxamic acid
Target:  

HDAC Autophagy Mitophagy Filovirus Apoptosis HPV

Research Areas:  

Infection Cancer

Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC6 and HDAC7 (Class II) and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis . Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification .
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2
AES-135
AES-135
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2 Cited Publications
Cat. No.: HY-114483
CAS No.: 2361659-61-0
Purity:  98.21%
Target:  

HDAC

Research Areas:  

Cancer

AES-135, a hydroxamic acid-based pan-HDAC inhibitor, prolongs survival in an orthotopic mouse model of pancreatic cancer. AES-135 inhibits HDAC3, HDAC6, HDAC8, and HDAC11 with IC50s ranging from 190-1100 nM .
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SH5-07
SH5-07
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1 Cited Publications
Cat. No.: HY-100494
CAS No.: 1456632-41-9
Target:  

STAT

Research Areas:  

Cancer

SH5-07 is a hydroxamic acid based Stat3 inhibitor with an IC50 of 3.9 μM in in vitro assay .
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MMP-8 inhibitor-1
MMP-8 inhibitor-1
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1 Cited Publications
Cat. No.: HY-128133
CAS No.: 236403-25-1
Purity:  99.70%
Synonyms: MMP8-I
Target:  

MMP

Research Areas:  

Cancer

MMP-8 inhibitor-1 (compound 21), a hydroxamic acid derivative, is a potent MMP-8 inhibitor without significant oral bioavailability .
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Remetinostat
Remetinostat
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1 Cited Publications
Cat. No.: HY-100365
CAS No.: 946150-57-8
Purity:  ≥98.0%
Synonyms: SHP-141
Target:  

HDAC

Research Areas:  

Inflammation/Immunology Cancer

Remetinostat (SHP-141) is a hydroxamic acid-based histone deacetylase (HDAC) inhibitor. Remetinostat alleviates Imiquimod (HY-B0180)-induced psoriatic dermatitis. Remetinostat can be used for study of cutaneous T-cell lymphoma .
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Suberoyl bis-hydroxamic acid
Suberoyl bis-hydroxamic acid
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Cat. No.: HY-W009776
CAS No.: 38937-66-5
Synonyms: Suberohydroxamic acid; SBHA
Target:  

HDAC Apoptosis

Research Areas:  

Cancer

Suberoyl bis-hydroxamic acid (Suberohydroxamic acid; SBHA) is a competitive and cell-permeable HDAC1 and HDAC3 inhibitor with ID50 values of 0.25 μM and 0.30 μM, respectively .Suberoyl bis-hydroxamic acid renders MM cells susceptible to apoptosis and facilitates the mitochondrial apoptotic pathways .Suberoyl bis-hydroxamic acid can be used for the study of medullary thyroid carcinoma (MTC) .
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Vorinostat (Standard)
Vorinostat (Standard)
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Cat. No.: HY-10221R
CAS No.: 149647-78-9
Synonyms: SAHA (Standard); Suberoylanilide hydroxamic acid (Standard)
Target:  

Reference Standards HDAC Autophagy Mitophagy Filovirus Apoptosis HPV

Research Areas:  

Infection Cancer

Vorinostat (Standard) is the analytical standard of Vorinostat. This product is intended for research and analytical applications. Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC6 and HDAC7 (Class II) and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis . Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification .
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Albizziin
Albizziin
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Cat. No.: HY-N12109
CAS No.: 585-23-9
Category:  

Microorganisms Ketones, Aldehydes, Acids 500 - Internal Server Error | MedChemExpress

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