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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
242 Results for "
hydroxysteroid
" in MedChemExpress (MCE) Product Catalog:
Products (242)
242 Results for "hydroxysteroid" in MCE Product Catalog:
17
Target:
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
4
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3
3
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Research Areas:
Diethylstilbestrol is a non-steroidal female hormone that has oral activity and can act on menopausal and postmenopausal disorders. Diethylstilbestrol can induce DNA oxidation and Apoptosis of spermatogonial stem cells. Diethylstilbestrol can induce thymocyte Autophagy Diethylstilbestrol is a 11β-hydroxysteroid dehydrogenase 2 (HSD11B2) inhibitor. .
3
Category:
Monophenols Disease markers Metabolic Disease Endocrine diseases Phenols Nervous System Disorder Endogenous metabolite Disease Research Fields Steroids
Target:
2
Category:
Human Gut Microbiota Metabolites Immune System Disorder Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Endocrinology Steroids
Target:
2
2 Cited Publications
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Research Areas:
BI 3231, a chemical probe, is a potent and selective hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) inhibitor, with IC50s of 1 and 13 nM for hHSD17B13 and mHSD17B13, respectively. BI 3231 has the potential for the research of nonalcoholic steatohepatitis (NASH) and other liver diseases .
2
2 Cited Publications
Category:
Natural Products Animals Marine natural products Other marine organisms Disease Research Fields Cancer
Target:
1
1 Cited Publications
Cat. No.: HY-18055
CAS No.: 376638-65-2
Target:
Research Areas:
BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 52 nM.
1
1 Cited Publications
Cat. No.: HY-113850
CAS No.: 1038713-54-0
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Research Areas:
CPSA is a potent and competitive inhibitor against 20α-hydroxysteroid dehydrogenase (AKR1C1) with a Ki value of 0.86 nM. CPSA is promising for research of lung and endometrial cancers, premature birth and neuronal disorders .
1
1 Cited Publications
Cat. No.: HY-P7604
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AKR1C3; Aldo-Keto Reductase Family 1, Member C3 (3-Alpha hydroxysteroid Dehydrogenase, Type II), Isoform CRA_a; Prev. HSD17B5; Trans-1,2-Dihydrobenzene-1,2-Diol Dehydrogenase; PGFS; Type IIb 3-Alpha hydroxysteroid Dehydrogenase; Prostaglandin F Synthase; 3-Alpha-hydroxysteroid Dehydrogenase Type 2; KIAA0119; 17-Beta-hydroxysteroid Dehydrogenase Type 5; HAKRB; hydroxysteroid (17-Beta) Dehydrogenase 5; DDX; Dihydrodiol Dehydrogenase Type I; 3-Alpha hydroxysteroid Dehydrogenase, Type II; Indanol Dehydrogenase; Testosterone 17-Beta-Dehydrogenase 5; 3-Alpha-HSD Type 2; Chlordecone Reductase Homolog HAKRb; 17-Beta-HSD 5; Dihydrodiol Dehydrogenase X; HluPGFS; Dihydrodiol Dehydrogenase 3; HAKRe; 3-Alpha-HSD Type II, Brain; DD-3; HA1753; DDH1; DD3; Aldo-Keto Reductase Family 1 Member C3; Aldo-Keto Reductase Family 1, Member C3 (3-Alpha hydroxysteroid Dehydrogenase, Type II)
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P76666
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SULT2B1; Sulfotransferase 2B1; Sulfotransferase Family 2B Member 1; ST2B1; HSST2; Sulfotransferase Family Cytosolic 2B Member 1; Sulfotransferase Family, Cytosolic, 2B, Member 1; hydroxysteroid Sulfotransferase SULT2B1a; hydroxysteroid Sulfotransferase 2
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P81196
Synonyms: 3BHS1_HUMAN; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; 3-beta-HSD I; 3-beta-hydroxy-5-ene steroid dehydrogenase 1; 3-beta-hydroxy-Delta(5)-steroid dehydrogenase 1; EC:1.1.1.145; 3-beta-hydroxysteroid 3-dehydrogenase 1; EC:1.1.1.270; Delta-5-3-ketosteroid isomerase; Dihydrotestosterone oxidoreductase. EC:1.1.1.210; Steroid Delta-isomerase 1; EC:5.3.3.1; Trophoblast antigen FDO161G; 3BH; HSDB3A;
1
1 Cited Publications
Synonyms: 4-Androsten-11β-ol-3,17-dione
Target:
1
1 Cited Publications
Cat. No.: HY-P72237
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HSD11B1; Short Chain Dehydrogenase/Reductase Family 26C Member 1; Prev. HSD11; HSD11L; Prev. HSD11B; 11-DH; SDR26C1; Short Chain Dehydrogenase/Reductase Family 26C, Member 1; Corticosteroid 11-Beta-Dehydrogenase Isozyme 1; hydroxysteroid (11-Beta) Dehydro
Species:
Human
Source:
E. coli
Target:
Research Areas:
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Research Areas:
3α-Hydroxysteroid Dehydrogenase, Microorganism (3α-HSD) is an enzyme encoded by the AKR1C4 gene, which can catalyze the conversion of 3-ketosteroids into 3α-hydroxy compounds. 3α-Hydroxysteroid dehydrogenase plays an important role in the inactivation of androgen DHT, and can convert DHT into 3α-androstanediol with weak androgen activity, which can be used in the research of hirsutism .
Cat. No.: HY-18053
CAS No.: 1024033-43-9
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Research Areas:
AZD 4017 is a potent, selective 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) inhibitor, with an IC50 of 7 nM.
Synonyms: Δ4-Abiraterone; CB-7627; Abiraterone D4A metabolite
Target:
Research Areas:
D4-abiraterone is a major metabolite of abiraterone. D4-abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid-5a-reductase (SRD5A) and also an antagonist of androgen receptor.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
