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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
hypercoagulability
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "hypercoagulability" in MCE Product Catalog:
Cat. No.: HY-P99012
CAS No.: 1236278-28-6
Synonyms: ALD-518; BMS-945429
Target:
Research Areas:
Clazakizumab (ALD-518; BMS-945429) is a monoclonal antibody inhibitor targeting IL-6 that binds to and blocks IL-6-mediated signaling (including trans-signaling), reducing STAT3 phosphorylation, innate immune cell infiltration, endothelial activation, and complement activation, thereby protecting the kidney from ischemia-reperfusion injury. Clazakizumab can be used in research on renal ischemia-reperfusion injury and obesity-related hypercoagulability .
Cat. No.: HY-143477
CAS No.: 2720619-72-5
Research Areas:
Factor XI-IN-1 is an activator inhibitor of coagulation factor XI (Factor XI) with an EC50 of 25.14 nM. Factor XI-IN-1 is applicable to research related to thrombosis, embolism, hypercoagulable states and fibrotic changes .
Cat. No.: HY-167858
CAS No.: 673485-33-1
Target:
Research Areas:
LK-732 is a thrombin inhibitor with anti-thrombotic activity.LK-732 has a dose-dependent inhibition of hypercoagulability in the model, with an IC50 of 1.3 mg/kg. LK-732 can be used in cardiovascular and cerebrovascular research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
