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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
imide
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "imide" in MCE Product Catalog:
Cat. No.: HY-W021005
CAS No.: 189114-61-2
Synonyms: Silver triflimide
Cat. No.: HY-W010937
CAS No.: 174899-83-3
Synonyms: BMIM-TFSI; BMI-TFSI
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1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (BMIM-TFSI; BMI-TFSI) is an HIV-1 integrase inhibitor. 1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide weakly inhibits recombinant HIV-1 integrase 3'-processing or strand transfer activity. 1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide can be used for the research of HIV-1 .
Cat. No.: HY-W002878
CAS No.: 144222-34-4
Cat. No.: HY-W127701
CAS No.: 623580-02-9
Synonyms: 1-Butyl-1-methylpiperidinium bis(trifluoromethylsulfonyl)imide
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TNF-α-IN-8 (compound I-42) is a TNF-α inhibitor. TNF-α-IN-8 is an isoindole-imide compound. TNF-α-IN-8 can be used for the research of cancer, heart disease, osteoporosis, inflammatory, allergic and autoimmune diseases . TNF-α-IN-8 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-172368
Research Areas:
PROTAC IKZF3 degrader-1 is a potent dual-targeting agent that functions as both a CARM1 inhibitor (IC50 = 2 nM) and a CRBN-dependent PROTAC degrader of IKZF3. PROTAC IKZF3 degrader-1 simultaneously inhibits CARM1 activity (reducing BAF155 methylation) and recruits CRBN to induce the targeted degradation of IKZF1, IKZF3, ZFP91, and FGD3 proteins; this leads to the downregulation of oncogenes, more potent induction of apoptosis, and the overcoming of immunomodulatory imide drugs resistance. PROTAC IKZF3 degrader-1 is suitable for research into both IMiD-sensitive and IMiD-resistant multiple myeloma .
Cat. No.: HY-169140
CAS No.: 114298-18-9
Synonyms: WY-47846
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Zalospirone (WY-47846) is a novel cyclic imide with 5-HT1A partial agonist activity. Zalospirone shows antidepressant efficacy .
Cat. No.: HY-121578
CAS No.: 58298-77-4
Synonyms: GDHB
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Agaridoxin (GDHB) is a blocker of catecholamine and adrenergic alpha-type receptors isolated from mushrooms. Agaridoxin activates adenylyl cyclase in rat hypothalamic membrane granules in the presence of guanosyl imide diphosphate (Gpp(NH)p) .
Cat. No.: HY-N14652
CAS No.: 99260-73-8
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Cat. No.: HY-W726159
CAS No.: 827027-25-8
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Choline bis(trifluoromethylsulfonyl)imide is an ionic liquid. Choline bis(trifluoromethylsulfonyl)imide can be used to extract phenols and organic compounds from aqueous solutions. Choline bis(trifluoromethylsulfonyl)imide can also be used as an electrolyte for low-temperature electrochemical energy storage .
Cat. No.: HY-W539941
CAS No.: 129135-87-1
Cat. No.: HY-N19775
CAS No.: 76970-77-9
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Cat. No.: HY-128408
CAS No.: 2893795-12-3
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PROTAC BTK Degrader-4 (compound 15) is a potent PROTAC Bruton's tyrosine kinases (BTK) degrader (DC50 < 100 nM) with little immunomodulatory imide drug (IMiD) activity (DC50 = 0.345 μM, Dmax = 27.4%). PROTAC BTK Degrader-4 can be used for cancers, autoimmune diseases, and inflammatory diseases that are mediated by BTK .
Cat. No.: HY-112453
CAS No.: 623163-52-0
IMDNQ1 is a Trypanosoma cruzi inhibitor derived from 1,4-naphthoquinone substituted with cyclic imide. IMDNQ1 effectively inhibits the proliferation of Trypanosoma cruzi epimastigotes, while also reducing the viability of mouse fibroblasts. The selectivity index between the antiproliferative activity and cytotoxicity of IMDNQ1 is 60.25, indicating a certain level of safety. IMDNQ1 can be widely used in studies related to Chagas disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
