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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
iminosugar
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "iminosugar" in MCE Product Catalog:
9
Category:
Plant Fagopyrum esculentum Moench Extract Metabolic Disease Disease Research Fields Polygonaceae Extract Saccharides Monosaccharides
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3
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SP187 is a host-targeted iminosugar with activity against filovirus infections in vitro and in vivo. SP187 is active against influenza and dengue in vivo.
Synonyms: ACT-519276; OGT2378
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Sinbaglustat (OGT2378) is a dual inhibitor of glucosylceramide synthase (GCS) and non-lysosomal glucosyl ceramidase (GBA2). Sinbaglustat is an orally available N-alkyl iminosugar that crosses the blood-brain barrier. Sinbaglustat can be used for the research of central neurodegenerative diseases associated with lysosomal dysfunctions .
Cat. No.: HY-14829F
CAS No.: 202979-51-9
Synonyms: 5-epi-Isofagomine
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L-Afegostat (5-epi-Isofagomine) is a glycosidase inhibitor. L-Afegostat is an iminosugar that can be used for the synthesis of carbohydrates. L-Afegostat shows enzyme inhibition to β-Glucosidase with an Ki of 30 μM .
Cat. No.: HY-190499
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Parasite NOD-like Receptor (NLR) Interleukin Related Caspase TNF Receptor Reactive Oxygen Species (ROS)
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Anti-inflammatory agent 128 is a 2-azido-3-O-benzyl-2-deoxy sp 2-iminosugar glycolipid with anti-inflammatory, antitumor, and antiparasitic activities. Anti-inflammatory agent 128 exhibits broad-spectrum antiproliferative activity against multiple human tumor cell lines. Anti-inflammatory agent 128 elevates mitochondrial ROS levels in Leishmania donovani promastigotes. Anti-inflammatory agent 128 inhibits the inflammatory response of Bv.2 microglia under LPS stimulation, suppresses NLRP3 inflammasome activation, downregulates the pro-inflammatory mediators Tnfa, Il1β, and Il6, and upregulates Hmox1. Anti-inflammatory agent 128 attenuates reactive gliosis in isolated retinal explants from diabetic rats and ameliorates inflammation-related phenotypes associated with diabetic retinopathy. Anti-inflammatory agent 128 can be used in research on tumors, leishmaniasis, and diabetic retinopathy .
Cat. No.: HY-N20714
CAS No.: 197449-09-5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
