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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
integrin-linked kinase
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "integrin-linked kinase" in MCE Product Catalog:
12
12 Publications Verification
Cat. No.: HY-18676
CAS No.: 2070015-22-2
OSU-T315 (ILK-IN-1) is a small Integrin-linked kinase (ILK) inhibitor with an IC50 of 0.6 μM, inhibiting PI3K/AKT signaling by dephosphorylation of AKT-Ser473 and other ILK targets (GSK-3β and myosin light chain) . OSU-T315 abrogates AKT activation by impeding AKT localization in lipid rafts and triggers caspase-dependent apoptosis in an ILK-independent manner . OSU-T315 causes cell death through apoptosis and autophagy .
2
2 Cited Publications
Cat. No.: HY-N0031
CAS No.: 104777-68-6
2
2 Cited Publications
Target:
Research Areas:
12-HETE, a major metabolic product of arachidonic acid using 12-LOX catalysis, inhibits cell apoptosis in a dose-dependent manner. 12-HETE promotes the activation and nuclear translocation of NF-κB through the integrin-linked kinase (ILK) pathway .12-HETE has both anti-thrombotic and pro-thrombotic effects . 12-HETE is a neuromodulator .
2
2 Cited Publications
Target:
Research Areas:
12-HETE-d8 is the deuterium labeled 12-HETE. 12-HETE, a major metabolic product of arachidonic acid using 12-LOX catalysis, inhibits cell apoptosis in a dose-dependent manner. 12-HETE promotes the activation and nuclear translocation of NF-κB through the integrin-linked kinase (ILK) pathway .12-HETE has both anti-thrombotic and pro-thrombotic effects . 12-HETE is a neuromodulator .
Cat. No.: HY-P76438
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ILKAP; ILKAP2; ILK Associated Serine/Threonine Phosphatase; ILKAP3; integrin-linked kinase-Associated Serine/Threonine Phosphatase 2C; Truncated integrin-linked kinase-Associated Serine/Threonine Phosphatase 2C; PPM1O; integrin-linked kinase-Associated Se
Species:
Human
Source:
HEK293
Cat. No.: HY-N0031R
CAS No.: 104777-68-6
Cat. No.: HY-177912
CAS No.: 1333146-87-4
Target:
Research Areas:
ILK-IN-4 (compound 49) is an integrin-linked kinase (ILK) inhibitor. ILK-IN-4 can be used for cancer research .
Cat. No.: HY-P7493
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PARVA; Alpha-Parvin; Prev. MXRA2; FLJ10793; Actopaxin; CH-ILKBP; Calponin-Like integrin-linked kinase-Binding Protein; Matrix-Remodelling Associated 2; Matrix-Remodeling-Associated Protein 2; Parvin Alpha; FLJ12254
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
