78 Results for "

internal standard

" in MedChemExpress (MCE) Product Catalog:
Products (78)

78 Results for "internal standard" in MCE Product Catalog:

78
Cilengitide
Cilengitide
0 Images
78 Publications Verification
Cat. No.: HY-16141
CAS No.: 188968-51-6
Synonyms: EMD 121974
Target:  

Integrin TGF-β Receptor Apoptosis PD-1/PD-L1 STAT Akt mTOR

Cilengitide (EMD 121974) is an integrin (integrin) inhibitor with blood-brain barrier permeability, with IC50 values against human targets as follows: 0.61 nM for αvβ3, 8.4 nM for αvβ5, 14.9 nM for α5β1, 5400 nM for αIIbβ3, 2050 nM for αvβ6, 2350 nM for αvβ8. Cilengitide inhibits the binding of integrins to vitronectin, fibronectin, fibrinogen and LAP (TGF-β), and serves as an internal standard for solid-phase integrin binding assays. Cilengitide inhibits tumor cell viability, induces apoptosis, reduces the phosphorylation levels of STAT3, AKT and mTOR, downregulates the expression of PD-L1, inhibits cell viability and angiogenesis, regulates anti-tumor immune responses and slows tumor growth. Cilengitide can be used in research related to glioblastoma, melanoma, advanced solid tumors and refractory brain tumors .
loading...
    loading...
View All Sizes
78
Cilengitide TFA
Cilengitide TFA
0 Images
78 Publications Verification
Cat. No.: HY-16143
CAS No.: 199807-35-7
Synonyms: EMD 121974 TFA
Target:  

Integrin TGF-β Receptor Apoptosis PD-1/PD-L1 STAT Akt mTOR

Cilengitide TFA (EMD 121974 TFA) is an integrin (integrin) inhibitor with blood-brain barrier permeability, with IC50 values against human targets as follows: 0.61 nM for αvβ3, 8.4 nM for αvβ5, 14.9 nM for α5β1, 5400 nM for αIIbβ3, 2050 nM for αvβ6, 2350 nM for αvβ8. Cilengitide TFA inhibits the binding of integrins to vitronectin, fibronectin, fibrinogen and LAP (TGF-β), and serves as an internal standard for solid-phase integrin binding assays. Cilengitide TFA inhibits tumor cell viability, induces apoptosis, reduces the phosphorylation levels of STAT3, AKT and mTOR, downregulates the expression of PD-L1, inhibits cell viability and angiogenesis, regulates anti-tumor immune responses and slows tumor growth. Cilengitide TFA can be used in research related to glioblastoma, melanoma, advanced solid tumors and refractory brain tumors .
loading...
    loading...
View All Sizes
23
D-Glucose-13C6
D-Glucose-13C6
0 Images
23 Cited Publications
Cat. No.: HY-B0389A
CAS No.: 110187-42-3
Synonyms: Glucose-13C6; D-(+)-Glucose-13C6; Dextrose-13C6
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

D-Glucose- 13C6 is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose- 13C6 can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard .
loading...
    loading...
View All Sizes
2
N6-Methyladenosine (Standard)
N6-Methyladenosine (Standard)
0 Images
2 Cited Publications
Cat. No.: HY-N0086R
CAS No.: 1867-73-8
Synonyms: 6-Methyladenosine (standard); N-Methyladenosine (standard)
Category:  

Natural Products Microorganisms Endogenous metabolite

Target:  

Endogenous Metabolite Influenza Virus Reference Standards

N6-Methyladenosine (Standard) is the analytical standard of N6-Methyladenosine. This product is intended for research and analytical applications. N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities. In Vitro: N6-methyladenosine (m6A) is selectively recognized by the human YTH domain family 2 (YTHDF2) protein to regulate mRNA degradation. N6-methyladenosine (m6A), a prevalent internal modification in the messenger RNA of all eukaryotes, is post-transcriptionally installed by m6A methyltransferase (e.g., MT-A70) within the consensus sequence of G(m6A)C (70%) or A(m6A)C (30%). N6-methyladenosine (m6A)-containing RNAs are greatly enriched in the YTHDF-bound portion and diminished in the flow-through portion . N6-methyladenosine (m6A), the most abundant internal RNA modification, functions in diverse biological processes, including regulation of embryonic stem cell self-renewal and differentiation. N6-methyladenosine (m6A) is a large protein complex, consisting in part of methyltransferase-like 3 (METTL3) and methyltransferase-like 14 (METTL14) catalytic subunits .
loading...
    loading...
View All Sizes
1
(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH
(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH
0 Images
1 Cited Publications
Cat. No.: HY-P0048
CAS No.: 52435-06-0
Synonyms: Surfagon
Target:  

GnRH Receptor

Research Areas:  

Others

(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (Surfagon, Mwt 1167.34 Da) is an agonist of gonadotropin-releasing hormone (GnRH). (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH can be used as an internal standard for the LC-MS analysis of leuprorelide acetate. (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH has potential applications in biochemical analysis and fertility .
loading...
    loading...
View All Sizes
Methyl heptadecanoate
Methyl heptadecanoate
0 Images
Cat. No.: HY-W004290
CAS No.: 1731-92-6
Synonyms: Methyl margarate
Category:  

Animals Other Diseases Lipids Disease Research Fields

Target:  

Biochemical Assay Reagents

Methyl heptadecanoate (Methyl margarate) is a methyl ester derivative of heptadecanoic acid (HY-W004284). Methyl heptadecanoate is used as an internal standard for the quantitative calibration of fatty acids in GC-MS analysis .
loading...
    loading...
View All Sizes
Methyl nonadecanoate
Methyl nonadecanoate
0 Images
Cat. No.: HY-W004262
CAS No.: 1731-94-8
Target:  

Biochemical Assay Reagents

Research Areas:  

Others

Methyl nonadecanoate is an internal standard. Methyl nonadecanoate can be used to determine the content of fatty acid methyl esters (FAME) in biodiesel .
loading...
    loading...
View All Sizes
16-Hydroxyhexadecanoic acid
16-Hydroxyhexadecanoic acid
0 Images
Cat. No.: HY-W068212
CAS No.: 506-13-8
Synonyms: Juniperic acid
Target:  

Drug Intermediate

Research Areas:  

Metabolic Disease

16-Hydroxyhexadecanoic acid (Juniperic acid) is one of the main monomers of cutin in Vicia faba flower petals. 16-Hydroxyhexadecanoic acid can be used as an internal standard for the measurement of hydroxy and hydroperoxy fatty acids in plasma .
loading...
    loading...
View All Sizes
Cyclosporin D
Cyclosporin D
0 Images
Cat. No.: HY-W019721
CAS No.: 63775-96-2
Category:  

Natural Products Microorganisms Disease Research Fields Inflammation/Immunology

Target:  

Nuclear Factor of activated T Cells (NFAT)

Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A . Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc) .
loading...
    loading...
View All Sizes
3,4,5-Trichloropyridine
3,4,5-Trichloropyridine
0 Images
Cat. No.: HY-W016371
CAS No.: 33216-52-3
Synonyms: 3,4,5-threechlorine pyridine
3,4,5-Trichloropyridine is a chlorinated pyridine compound and also serves as an internal standard for quantitative proton nuclear magnetic resonance spectroscopy .
loading...
    loading...
View All Sizes
C17 Ceramide (d18:1/17:0)
C17 Ceramide (d18:1/17:0)
0 Images
Cat. No.: HY-115703
CAS No.: 67492-16-4
Synonyms: N-Heptadecanoyl-D-erythro-sphingosine
Target:  

Biochemical Assay Reagents

Research Areas:  

Metabolic Disease

C17 Ceramide (d18:1/17:0) (N-Heptadecanoyl-D-erythro-sphingosine) is a phospholipid internal standard. C17 Ceramide (d18:1/17:0) is used in studies of medium-chain acyl-CoA dehydrogenase deficiency (MCADD) .
loading...
    loading...
View All Sizes
Methyl heptadecanoate-d33
Methyl heptadecanoate-d33
0 Images
Cat. No.: HY-W004290S
CAS No.: 1219804-81-5
Methyl heptadecanoate-d33 is the deuterium labeled Methyl heptadecanoate (HY-W004290). Methyl heptadecanoate (C17:0 methyl ester) is the methyl ester derivative of heptadecanoic acid (HY-W004284). Methyl heptadecanoate is used as an internal standard for quantitative calibration of fatty acids in GC-MS analysis .
loading...
    loading...
View All Sizes
5α-Cholestane
5α-Cholestane
0 Images
Cat. No.: HY-133970
CAS No.: 481-21-0
Purity:  99.34%
Target:  

Biochemical Assay Reagents Drug Intermediate

Research Areas:  

Inflammation/Immunology

5α-Cholestane is a steroidal hydrocarbon and fecal stanol, and is used as an internal standard for gas chromatographic sterol analysis. 5α-Cholestane is the parent steroidal skeleton of polyhydroxylated brassinosteroids of plant origin. It is used as an internal standard for GC-FID and GC-MS analysis of fecal sterols in urine and sludge samples. 5α-Cholestane can be used in studies of age- or disease-related skeletal muscle atrophy .
loading...
    loading...
View All Sizes
(Des-Pyr1)-LHRH
(Des-Pyr1)-LHRH
0 Images
Cat. No.: HY-P4463
CAS No.: 38280-53-4
Target:  

GnRH Receptor

Research Areas:  

Others

(Des-Pyr1)-LHRH is a Polypeptide Internal Standard, identical to (Des-Pyr1)-GnRH, which can be identified through peptide screening. Peptide screening is a research tool that mainly collects active polypeptides via immunoassays. It can be applied to protein interaction, functional analysis, epitope screening, especially in the field of active molecule research and development. (Des-Pyr1)-LHRH can serve as an internal standard (ISTD) for mass spectrometry analysis .
loading...
    loading...
View All Sizes
1,2-Distearoyl-sn-glycerol
1,2-Distearoyl-sn-glycerol
0 Images
Cat. No.: HY-112552
CAS No.: 10567-21-2
Purity:  ≥98.0%
Synonyms: DSG; 1,2-Dioctadecanoyl-sn-glycerol
Category:  

Other Diseases Lipids Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Biochemical Assay Reagents

1,2-Distearoyl-sn-glycerol (DSG) is a glyceride compound. 1,2-Distearoyl-sn-glycerol can be used as an internal standard for the analysis of molecular species of diacylglycerol (DAG) and other phospholipids in rat brain .
loading...
    loading...
View All Sizes
Sphinganine-C17
Sphinganine-C17
0 Images
Cat. No.: HY-141632
CAS No.: 32164-02-6
Synonyms: Heptadecasphinganine
Target:  

Bacterial

Research Areas:  

Infection Neurological Disease

Sphinganine-C17 (Heptadecasphinganine) is a synthetic bioactive sphingolipid and an isomer of sphinganine. Sphinganine-C17 inhibits the growth of Candida glabrata and Candida albicans with a minimum bactericidal concentration (MBC) of 0.5 μg/mL for both. Sphinganine-C17 can be used as an internal standard for the chromatographic analysis of sphingosine compounds .
loading...
    loading...
View All Sizes
6α-Fluoroprednisolone
6α-Fluoroprednisolone
0 Images
Cat. No.: HY-107935
CAS No.: 53-34-9
Purity:  95.93%
Synonyms: Fluprednisolone
Target:  

Biochemical Assay Reagents

Research Areas:  

Inflammation/Immunology

6α-Fluoroprednisolone (Fluprednisolone) serves as the internal standard for Methylprednisolone (HY-B0260), Prednisolone (HY-17463), and Prednisone (HY-B0214). 6α-Fluoroprednisolone is an anti-inflammatory agent with anti-inflammatory activity. 6α-Fluoroprednisolone exhibits thymolytic activity. 6α-Fluoroprednisolone functions as a natriuretic agent .
loading...
    loading...
View All Sizes
2-Ethylbutyric acid
2-Ethylbutyric acid
0 Images
Cat. No.: HY-W004154
CAS No.: 88-09-5
Category:  

Geraniaceae Extract Ketones, Aldehydes, Acids Other Diseases 500 - Internal Server Error | MedChemExpress

Oops!

Sorry, Something went wrong on our server.
Our team has been notified and is working to fix the issue.