12 Results for "

lysosomotropic

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "lysosomotropic" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-138540
CAS No.: 4303-67-7
Purity:  99.78%
Synonyms: N-Dodecylimidazole
1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes, disruption of the lysosomal membrane, and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity .
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2
2 Cited Publications
Cat. No.: HY-100621
CAS No.: 93565-01-6
Purity:  ≥98.0%
Target:  

Monoamine Oxidase

Research Areas:  

Neurological Disease

MDL 72527 is a potent polyamine oxidase (PAO) inhibitor. MDL 72527 shows a lysosomotropic effect. MDL 72527 shows neuroprotective effects .
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1
1 Cited Publications
Cat. No.: HY-103691A
CAS No.: 1700693-96-4
Purity:  99.54%
Target:  

Autophagy Apoptosis

Research Areas:  

Cancer

ARN5187 trihydrochloride is a lysosomotropic REV-ERBβ ligand with a dual inhibitory activity toward REV-ERB-mediated transcriptional regulation and autophagy. ARN5187 trihydrochloride shows lysosomotropic potency and cytotoxicity. ARN5187 trihydrochloride induces apoptosis .
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Cat. No.: HY-112897
CAS No.: 1807988-47-1
Purity:  98.18%
Target:  

Autophagy PI3K Apoptosis

Research Areas:  

Cancer

IITZ-01 is a potent lysosomotropic autophagy inhibitor with single-agent antitumor activity, with an IC50 of 2.62 μM for PI3Kγ.
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Cat. No.: HY-W335972
CAS No.: 1541-67-9
Target:  

Phosphatase

Research Areas:  

Others

N-Lauryldiethanolamine is an antistatic agent with a strong inhibitory effect on cell growth at 30 μM, showing some lysosomotropic behavior. N-Lauryldiethanolamine is toxic at a concentration of ≥10 μM in the osteogenesis inhibition assay .
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Cat. No.: HY-103691
CAS No.: 1287451-26-6
Target:  

Autophagy Apoptosis

Research Areas:  

Cancer

ARN5187 is a lysosomotropic REV-ERBβ ligand with a dual inhibitory activity toward REV-ERB-mediated transcriptional regulation and autophagy. ARN5187 shows lysosomotropic potency and cytotoxicity. ARN5187 induces apoptosis .
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Cat. No.: HY-W680647
CAS No.: 99207-33-7
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease

MDL 72527 free base is a potent polyamine oxidase (PAO) inhibitor. MDL 72527 free base shows a lysosomotropic effect. MDL 72527 shows neuroprotective effects .
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Cat. No.: HY-168206
Target:  

Autophagy

Research Areas:  

Cancer

Autophagy-IN-6 (compound 1u) is a lysosomotropic autophagy inhibitor and can induces LC3-II protein accumulation. Autophagy-IN-6 shows anti-proliferative activity .
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Cat. No.: HY-203817
CAS No.: 1807988-46-0
Research Areas:  

Cancer

IITZ-02 is a lysosomotropic Autophagy inhibitor. IITZ-02 enhances autophagosome accumulation but inhibits autophagosomal degradation by impairing lysosomal function, finally inducing the inhibition of autophagy. IITZ-02 abolishes mitochondrial membrane potential and induces apoptosis through the mitochondria-mediated pathway. IITZ-02 has a potent antitumor activity in MDA-MB-231 xenograft mouse models. IITZ-02 can be used for cancers research .
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Cat. No.: HY-103691AR
CAS No.: 1700693-96-4
Research Areas:  

Cancer

ARN5187 trihydrochloride (Standard) is the analytical standard of ARN5187 trihydrochloride (HY-103691A). This product is intended for research and analytical applications. ARN5187 trihydrochloride is a lysosomotropic REV-ERBβ ligand with a dual inhibitory activity toward REV-ERB-mediated transcriptional regulation and autophagy. ARN5187 trihydrochloride shows lysosomotropic potency and cytotoxicity. ARN5187 trihydrochloride induces apoptosis .
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Cat. No.: HY-100621R
CAS No.: 93565-01-6
MDL 72527 (Standard) is the analytical standard of MDL 72527 (HY-100621). This product is intended for research and analytical applications. MDL 72527 is a potent polyamine oxidase (PAO) inhibitor. MDL 72527 shows a lysosomotropic effect. MDL 72527 shows neuroprotective effects .
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Cat. No.: HY-138540R
CAS No.: 4303-67-7
Synonyms: N-Dodecylimidazole (Standard)
1-Dodecylimidazole (Standard) is the analytical standard of 1-Dodecylimidazole. This product is intended for research and analytical applications. 1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes, disruption of the lysosomal membrane, and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity .
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