2 Results for "

microvascular disorders

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "microvascular disorders" in MCE Product Catalog:

Cat. No.: HY-106428
CAS No.: 169543-49-1
Synonyms: ITF1697
Icrocaptide (ITF1697) is a stable Lys-Pro-containing peptide that inhibits the intracellular Ca 2+-dependent fusion of Weibel-Palade bodies with the plasma membrane. Icrocaptide exerts its activity at the early stages of endothelial activation and inhibits P-selectin and von Willebrand factor secretion. Icrocaptide can be used for the study of a variety of microvascular disorders .
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Cat. No.: HY-185379
CAS No.: 3106554-00-8
Target:  

STING

Research Areas:  

Inflammation/Immunology

STING antagonist-3 is a potent STING antagonist with an IC50 of 2.3 nM against human wild-type STING. STING antagonist-3 inhibits human wild-type STING and the gain-of-function STING mutants N154S and V155M. STING antagonist-3 suppresses IFN‑α2a production in stimulated human whole blood. STING antagonist-3 inhibits IP-10 production in activated human dermal microvascular endothelial cells (HMVEC-d). STING antagonist-3 can be used for the research of autoimmune diseases, autoinflammatory diseases, interferonopathies, and fibrotic disorders .
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