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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
monocyte-derived cells
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "monocyte-derived cells" in MCE Product Catalog:
19
19 Cited Publications
Cat. No.: HY-P1846
CAS No.: 219127-21-6
19
19 Cited Publications
Cat. No.: HY-P1846A
Synonyms: 1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine; 19:0 Lyso PC
Target:
Research Areas:
Lysophosphatidylcholine C19:0 (19:0 Lyso PC) is a lysophosphatidylcholine with a fully saturated C19 acyl chain. When combined with LPS (HY-D1056), Lysophosphatidylcholine C19:0 induces the secretion of IL-1β by human monocyte-derived dendritic cells. Lysophosphatidylcholine C19:0 reduces the viability of monocyte-derived dendritic cells .
Cat. No.: HY-108661A
Purity: 97.4%
Target:
Research Areas:
NF546 (hydrate) is a selective non-nucleotide P2Y11 agonist with a pEC50 of 6.27. NF546 (hydrate) stimulates release of interleukin-8 from human monocyte-derived dendritic cells .
Cat. No.: HY-108661
CAS No.: 1006028-37-0
Target:
Research Areas:
NF546 is a selective non-nucleotide P2Y11 agonist with a pEC50 of 6.27. NF546 stimulates release of interleukin-8 from human monocyte-derived dendritic cells .
Cat. No.: HY-D2480
CAS No.: 2260795-60-4
Cat. No.: HY-P991366
Synonyms: AL008
Cat. No.: HY-146841S
CAS No.: 2342575-08-8
Synonyms: 1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine-d5; 19:0 Lyso PC-d5
Target:
Research Areas:
Lecithin-cholesterol acyltransferase C19:0-d5 (19:0 lecithin-cholesterol acyltransferase-d5) is the deuterated form of lecithin-cholesterol acyltransferase C19:0 (HY-154830). Lecithin-cholesterol acyltransferase C19:0 is a lysophosphatidylcholine with a fully saturated C19 acyl chain. When lecithin-cholesterol acyltransferase C19:0 is combined with LPS (HY-D1056), it can induce the secretion of IL-1β by human monocyte-derived dendritic cells. Lecithin-cholesterol acyltransferase C19:0 can reduce the survival rate of dendritic cells derived from monocytes.
Cat. No.: HY-186292
CAS No.: 1285684-41-4
Research Areas:
Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer
Mal-Val-Cit-PABC-Dexamethasone is a conjugate of the glucocorticoid receptor agonist Dexamethasone (HY-14648) and a ADC linker, which can be used for the synthesis of antibody-drug conjugates (ADC). Mal-Val-Cit-PABC-Dexamethasone is designed to deliver immunosuppressants to monocytes and/or monocyte-derived cells in a targeted manner .
Cat. No.: HY-181168
Target:
Research Areas:
Lb54 is a caspase-3 and caspase-7 activator with an EC50 of 660.9 nM for human procaspase-3. Lb54 activates caspase-3/7, which cleaves Gasdermin D (GSDMD) at aspartic acid residue 87 to generate a p10 fragment, preventing formation of the pore-forming p30 fragment of GSDMD. Lb54 suppresses GSDMD-mediated pyroptosis through caspase-3/7 activation, thereby attenuating inflammatory responses and conferring protection against sepsis. Lb54 alleviates acute lung injury, and inhibited systemic inflammation by restraining the maturation of monocyte-derived dendritic cells. Lb54 can be used for the research of sepsis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
