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31 Results for "

monocytic

" in MedChemExpress (MCE) Product Catalog:

Products (31)

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m-3M3FBS

10 Publications Verification

Cat. No.: HY-19619

CAS No.: 200933-14-8

Target:

Phospholipase Apoptosis

Research Areas:

Cancer

m-3M3FBS is a potent phospholipase C (PLC) activator. m-3M3FBS stimulates superoxide generation in human neutrophils, upregulates intracellular calcium concentration, and stimulates inositol phosphate generation in various cell lines. m-3M3FBS induces monocytic leukemia cell apoptosis .

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FSL-1 TFA

5 Cited Publications

Cat. No.: HY-P2036A

Target:

Toll-like Receptor (TLR) MMP HSV Antibiotic

Research Areas:

Infection

FSL-1 TFA, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection . FSL-1 TFA induces MMP-9 production through TLR2 and NF-κB/AP-1 signaling pathways in monocytic THP-1 cells .

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VAF347

3 Cited Publications

Cat. No.: HY-135750

CAS No.: 574759-62-9

Purity: 99.90%

Target:

Aryl Hydrocarbon Receptor

Research Areas:

Inflammation/Immunology

VAF347 is a cell permeable and highly affinity aryl hydrocarbon receptor (AhR) agonist and induces AhR signaling. VAF347 inhibits the development of CD14 ⁺CD11b ⁺ monocytes from granulo-monocytic (GM stage) precursors. VAF347 has anti-inflammatory effects .

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PROTAC RIPK degrader-2

1 Cited Publications

Cat. No.: HY-111866

CAS No.: 1801547-16-9

Purity: 99.89%

Target:

PROTACs RIP kinase TNF Receptor

Research Areas:

Metabolic Disease Cancer

PROTAC RIPK degrader-2 is a non-peptidic PROTAC degrader targeting RIPK2, with a DC₅₀ of 1.5 nM. PROTAC RIPK degrader-2 recruits VHL or cereblon E3 ubiquitin ligases, induces ubiquitination and proteasomal degradation of RIPK2, acts via substoichiometric catalysis, and inhibits downstream pro-inflammatory signaling pathways. PROTAC RIPK degrader-2 inhibits the NOD2/RIPK2 pathway and suppresses MDP (HY-127090)-stimulated TNFα release in human whole blood. PROTAC RIPK degrader-2 can be used in studies related to acute monocytic leukemia and glucose metabolism .

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KAT6A Antibody (YA6622)

1 Cited Publications

Cat. No.: HY-P86929

Synonyms: Histone acetyltransferase KAT6A EC:2.3.1.48 MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3 (MYST-3) monocytic leukemia zinc finger protein Runt-related transcription factor-binding protein 2 Zinc finger protein 220 KAT6A MOZ MYST3 RUNXBP2 Histone acetyltransferase KAT6A EC:2.3.1.48 MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3 (MYST-3) monocytic leukemia zinc finger protein Runt-related transcription factor-binding protein 2 Zinc finger protein 220 KAT6A MOZ MYST3 RUNXBP2 ZNF220

Host:

Rabbit

Application:

ICC/IF, IHC-P, FC, ChIP

Reactivity:

Human, Mouse, Rat

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