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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
184 Results for "
monooxygenase
" in MedChemExpress (MCE) Product Catalog:
Products (184)
184 Results for "monooxygenase" in MCE Product Catalog:
2
2 Cited Publications
Target:
Research Areas:
GSK180 is a selective, competitive, and potent inhibitor of kynurenine-3-monooxygenase (KMO), a key enzyme of tryptophan metabolism (IC50, ~6 nM), but shows negligible activity against other enzymes on the tryptophan pathway. GSK180 rapidly changes levels of kynurenine pathway metabolites, and acts as a useful tool to probe the therapeutic potential of KMO inhibition .
1
1 Cited Publications
Cat. No.: HY-W327449
CAS No.: 501-13-3
Target:
1
1 Cited Publications
Target:
Research Areas:
UPF-648 is a potent kynurenine 3-monooxygenase (KMO) inhibitor; exhibits highly active at 1 uM (81 ± 10% KMO inhibition); ineffective at blocking KAT activity.
1
1 Cited Publications
Cat. No.: HY-P75548A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: YWHAQ; Tyrosine 3-monooxygenase/Tryptophan 5-monooxygenase Activation Protein Theta; 14-3-3; HS1; Tyrosine 3-monooxygenase/Tryptophan 5-monooxygenase Activation Protein; Theta Polypeptide; 14-3-3 Protein T-Cell; 14-3-3 Protein Theta; 14-3-3 Protein Tau; P
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P73733
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: PAH; PH; Phenylalanine Hydroxylase; L-Phenylalanine Hydroxylase; Phenylalanine-4-Hydroxylase; PAH Protein; Phe-4-monooxygenase; PKU1; Phenylalanine 4-monooxygenase; PKU
Species:
Human
Source:
Sf9 insect cells
1
1
Target:
Research Areas:
Tetramethylthiuram monosulfide (TMTM) is an orally active microsomal monooxygenases inhibitor. Tetramethylthiuram monosulfide is used as an accelerator and activator in the processing of natural rubber and butyl rubber. Tetramethylthiuram monosulfide reduces palmitic acid incorporation into microsomal phospholipids, disrupts microsomal membrane integrity, and impairs electron transport during oxygenation. Tetramethylthiuram monosulfide can be used for the research of fungal infection, bacterial infection and allergic contact dermatitis .
1
1 Cited Publications
Cat. No.: HY-W015635
CAS No.: 2179-57-9
Cat. No.: HY-W748591
CAS No.: 76735-57-4
Cat. No.: HY-N9348A
CAS No.: 108844-81-1
Research Areas:
Glucoraphenin potassium is an orally effective glucosinolate. Glucoraphenin potassium can be isolated from radish sprouts. Glucoraphenin potassium enhances the enzymatic activity of Glutathione S-transferase. Glucoraphenin potassium enhances the activity of cytochrome P450-related monooxygenase .
Cat. No.: HY-W009247
CAS No.: 161696-76-0
Synonyms: N-Demethylolanzapine; LY170055
Target:
Research Areas:
N-Desmethylolanzapine is an antipsychotic drug.
The formation of N-Desmethylolanzapine correlates with the level and activity
of human liver flavin-containing monooxygenase (FMO3). N-Desmethylolanzapine
can be used in the study of antipsychotic drugs .
Cat. No.: HY-138126
CAS No.: 113527-49-4
Target:
Research Areas:
Cat. No.: HY-N11425
CAS No.: 36504-71-9
Category:
Target:
Cat. No.: HY-15500
CAS No.: 1008119-83-2
Target:
Research Areas:
JM6 is a weak kynurenine 3-monooxygenase (KMO) inhibitor with an IC50 of 19.85 μM for mouse KMO. JM6 can be used for Alzheimer's diseases research .
Target:
Research Areas:
Benzobarbital is an active low-toxicity inductor of the liver monooxygenase system. Benzobarbital raises cytochrome P-450 concentration. Benzobarbital can be used in the research of post-ischemic liver disease .
Cat. No.: HY-W327449R
CAS No.: 501-13-3
Target:
Cat. No.: HY-138126A
CAS No.: 350691-68-8
Dansyl-Tyr-Val-Gly TFA is a substrate of peptidylglycine monooxygenase (PHM), with a KD of 22 μM for PHM. Dansyl-Tyr-Val-Gly TFA can be used to investigate the catalytic mechanism, kinetics and inactivation characteristics of PHM .
Target:
Research Areas:
Tyrosine 3-monooxygenase (Tyrosine hydroxylase) is a rate-limiting enzyme in catecholamine biosynthesis and belongs to the family of aromatic amino acid hydroxylases. Tyrosine 3-monooxygenase catalyzes the initial and rate-limiting step in the biosynthetic pathway of catecholamines, including dopamine, noradrenaline, and adrenaline .
Cat. No.: HY-15600B
CAS No.: 1465017-87-1
Target:
Research Areas:
UPF-648 sodium salt is an effective inhibitor of kynurenine 3-monooxygenase (KMO), achieving approximately 81% inhibition at a concentration of 1uM, with no inhibitory effect on kynurenine aminotransferase (KAT).
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
