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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
noise
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "noise" in MCE Product Catalog:
27
27 Cited Publications
Cat. No.: HY-A0134
CAS No.: 26675-46-7
Target:
Isoflurane is a volatile anaesthetic. Isoflurane diminishs the effect of ROS activity. Isoflurane suppresses respiration. Isoflurane enables rapid anesthesia induction and emergence. Isoflurane protects against noise-induced hearing loss and tissue damage in mice. Isoflurane protects against renal ischemia and reperfusion injury and modulates leukocyte infiltration .
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Adenosine amine congener (ADAC) is a selective A1 adenosine receptor agonist, can ameliorate noise- and Cisplatin-induced cochlear injury. Adenosine amine congener also has neuroprotective effects .
Cat. No.: HY-D1590
CAS No.: 929679-22-1
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ODIPY Green 8-P2M is a novel thiol-reactive fluorescence probe based on the BODIPY fluorophore, the fluorescence is strongly quenched by d-PeT and then can be restored after reaction with thiol, resulting in an extremely high signal-to-noise ratio. ODIPY Green 8-P2M can be useful for detecting extremely low concentrations of protein in the gel after SDS-PAGE .
Cat. No.: HY-149836
Purity: 98.07%
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3-MeOARh-NTR is an activatable imaging probe with high selectivity, and good stability. 3-MeOARh-NTR possesses high selectivity and high signal-to-noise ratio for nitroreductase (NTR) detection, and serves as an efficient molecular tool for endogenous NTR detection .
Cat. No.: HY-B0612B
CAS No.: 185197-71-1
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(S)-Lercanidipine is a calcium channel blocker with antihypertensive and neuroprotective activities. (S)-Lercanidipine reduces oxidative stress and protects auditory sensory hair cells from noise-induced damage. (S)-Lercanidipine showed significant protective effects on cell viability in in vitro experiments, especially at low concentrations. (S)-Lercanidipine has been found to effectively reduce the hearing threshold of mice after noise stimulation and protect the survival of outer hair cells. The antioxidant properties of (S)-Lercanidipine are reflected in its increased expression of antioxidant enzyme genes and decreased expression of oxidative enzyme genes. (S)-Lercanidipine administration is effective in reducing noise-induced hearing loss both before and after noise exposure. (S)-Lercanidipine may alleviate noise-induced hearing loss and protect the survival of outer hair cells through its antioxidant mechanism .
Cat. No.: HY-149836A
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3-MeOARh-NTR chloride is an activatable imaging probe with high selectivity, and good stability. 3-MeOARh-NTR chloride possesses high selectivity and high signal-to-noise ratio for nitroreductase (NTR) detection, and serves as an efficient molecular tool for endogenous NTR detection .
Cat. No.: HY-D2953
Synonyms: CLIP-CPY
Cat. No.: HY-184527
CAS No.: 1372609-54-5
Synonyms: 2-Chloro-4-nitrophenyl ferulate
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CNPF (2-Chloro-4-nitrophenyl ferulate) is a chromogenic substrate of Feruloyl esterase A (derived from Aspergillus niger). CNPF can be hydrolyzed by this enzyme to release the chromophore. CNPF has a superior signal-to-noise ratio and is suitable for high-throughput screening of feruloyl esterase .
Cat. No.: HY-D2973
Cat. No.: HY-D3209
CAS No.: 2646628-35-3
Cat. No.: HY-P992580
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Mouse IgG2a lambda, Isotype Control is a mouse IgG2a isotype control monoclonal antibody. Mouse IgG2a lambda, Isotype Control precisely mimics nonspecific binding and Fc receptor background by maintaining the same heavy and light chain isotypes as the specific primary antibody, thereby effectively distinguishing specific signal from background noise in experiments. Mouse IgG2a lambda, Isotype Control can be used as a negative control in experiments such as flow cytometry and immunohistochemistry .
Cat. No.: HY-D3480
Cat. No.: HY-D3069
CAS No.: 2892545-08-1
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DNTPH is a near-infrared (NIR) aggregation-induced emission (AIE) fluorescent probe used for imaging β-amyloid (Aβ) aggregates. Designed by balancing hydrophobic and hydrophilic groups, DNTPH achieves selective binding to Aβ42 fibrils and generates a near-infrared fluorescent signal with high signal-to-noise ratio. Upon binding to Aβ42 fibrils, DNTPH exhibits enhanced fluorescence, while also inhibiting Aβ42 fibril formation, promoting fibril depolymerization, attenuating Aβ-induced neurotoxicity, and improving cognitive function in Alzheimer's disease (AD) mice. DNTPH can be used in Alzheimer's disease research .
Cat. No.: HY-D3438
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Photoswitchable PM8 is a fluorescent probe used for super-resolution imaging of the plasma membrane. Photoswitchable PM8 functions through a light-induced Z/E isomerization mechanism: in the hydrophobic cell membrane environment, the Z isomer forms a planar intramolecular charge transfer state stabilized by an intramolecular hydrogen bond, which restricts conformational freedom, reduces nonradiative decay, and produces bright fluorescence; in contrast, the E isomer lacks this hydrogen bond, has increased conformational freedom, and exhibits a fluorescence-quenched state. The fluorescence of Photoswitchable PM8 can be switched "on/off" by visible light: activation with 405 nm light forms the fluorescent Z isomer, and switching with 561 nm light converts it to the nonfluorescent E isomer. In the membrane environment, Photoswitchable PM8 enables single-molecule localization for super-resolution imaging. Due to solvent-induced quenching and aggregation, Photoswitchable PM8 has negligible fluorescence in aqueous solution, but upon binding to the hydrophobic membrane environment it produces bright fluorescence, enabling high signal-to-noise ratio imaging without washing .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
