67 Results for "

opener

" in MedChemExpress (MCE) Product Catalog:
Products (67)

67 Results for "opener" in MCE Product Catalog:

11
Minoxidil
Minoxidil
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11 Publications Verification
Cat. No.: HY-B0112
CAS No.: 38304-91-5
Synonyms: U10858
Category:  

Cardiovascular Disease Disease Research Fields Cancer

Target:  

Potassium Channel

Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM .
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9
GW9508
GW9508
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9 Cited Publications
Cat. No.: HY-15589
CAS No.: 885101-89-3
Purity:  99.23%
Target:  

Free Fatty Acid Receptor Potassium Channel

Research Areas:  

Cardiovascular Disease Metabolic Disease Inflammation/Immunology

GW9508 is a potent and selective G protein-coupled receptors FFA1 (GPR40) and GPR120 agonist with pEC50s of 7.32 and 5.46, respectively. GW9508 shows ~100-fold selectivity for GPR40 over GPR120. GW9508 is inactive against other GPCRs, kinases, proteases, integrins and PPARs. GW9508 is a glucose-sensitive insulin secretagogue and an ATP-sensitive potassium (KATP) channels opener. Anti-inflammatory and anti-atherosclerotic activities .
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5
Urolithin C
Urolithin C
0 Images
5 Cited Publications
Cat. No.: HY-135897
CAS No.: 165393-06-6
Purity:  ≥98.0%
Category:  

Metabolic Disease Phenols Polyphenols Endogenous metabolite Disease Research Fields

Target:  

Calcium Channel Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite

Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is a L-type Ca 2+ channel opener and enhances Ca 2+ influx. Urolithin C induces cell apoptosis through a mitochondria-mediated pathway and also stimulates reactive oxygen species (ROS) formation .
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4
NS-1619
NS-1619
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4 Cited Publications
Cat. No.: HY-12496
CAS No.: 153587-01-0
Purity:  98.06%
Target:  

Potassium Channel Apoptosis

Research Areas:  

Cardiovascular Disease Cancer

NS-1619 is an opener of large conductance Ca 2+-activated K + (BK) channel. NS-1619 is a highly effective relaxant with an EC50 of about 10 – 30 μM in several smooth muscles of blood vessels and other tissues . NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells .
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4
BMS-191011
BMS-191011
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4 Cited Publications
Cat. No.: HY-108593
CAS No.: 202821-81-6
Synonyms: BMS-A
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

BMS 191011 (BMS-A) is a potent BKCa channel opener (large-conductance Ca 2+-activated potassium channel). BMS-191011 shows neuroprotective activities in rodent models of stroke .
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3
Atractyloside A
Atractyloside A
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3 Cited Publications
Cat. No.: HY-N0237
CAS No.: 126054-77-1
Category:  

Terpenoids Sesquiterpenes Other Diseases Plants 500 - Internal Server Error | MedChemExpress

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