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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
osteoarthritic
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "osteoarthritic" in MCE Product Catalog:
13
13 Publications Verification
Synonyms: D-Glucosamine; Chitosamine
13
13 Publications Verification
Synonyms: D-(+)-Glucosamine hydrochloride; Chitosamine hydrochloride
13
4
4 Cited Publications
Cat. No.: HY-16781
CAS No.: 415903-37-6
Synonyms: CJ-023423; RQ-00000007; AAT-007
Target:
Research Areas:
Grapiprant (CJ-023423) is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2). Grapiprant displaces [ 3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor with IC50 value of 35 nM and Ki value of 24 nM. Grapiprant has the potential for osteoarthritic pain and inflammation treatment [3] .
Synonyms: LY3556050; CNTX-0290
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Research Areas:
Mazisotine (CNTX-0290) is an orally active, non-opioid somatostatin receptor 4 (SSTR4) agonist with an EC50 of 4.7 nM. Mazisotine exerts significant analgesic effects in various nociceptive (inflammatory, osteoarthritic) and neuropathic pain models. Mazisotine can be used for pain research .
Synonyms: D-(+)-Glucosamine hydrochloride (Standard); Chitosamine hydrochloride (Standard)
Category:
Cat. No.: HY-P5419A
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Research Areas:
Cat. No.: HY-10635
CAS No.: 808756-71-0
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Research Areas:
ABT-102 is a potent and highly selective Vanilloid Receptor (TRPV1) receptor antagonist. ABT-102 potently and reversibly increases heat pain thresholds and reduced painfulness of suprathreshold oral/cutaneous heat. ABT-102 reduces nociceptive responses of animals in models of inflammatory, bone cancer, postoperative, and osteoarthritic pain .
Cat. No.: HY-106586
CAS No.: 59017-64-0
Synonyms: P-286
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Research Areas:
Ioxaglic acid (P-286) is negatively charged contrast agent, is useful as an inverse indicator for glycosaminoglycan (GAG) used in computed tomography (CT). Ioxaglic acid can be used for imaging of human osteoarthritic cartilage via quantitative assessment of glycosaminoglycan content .
Cat. No.: HY-139207
CAS No.: 1296149-08-0
Cat. No.: HY-139207A
CAS No.: 1296149-13-7
Cat. No.: HY-139347A
CAS No.: 2919211-45-1
Synonyms: LY3556050 tartrate; CNTX-0290 tartrate
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Research Areas:
Mazisotine (CNTX-0290) tartrate is an orally active, non-opioid somatostatin receptor 4 (SSTR4) agonist with an EC50 of 4.7 nM. Mazisotine tartrate exerts significant analgesic effects in various nociceptive (inflammatory, osteoarthritic) and neuropathic pain models. Mazisotine tartrate can be used for pain research .
Cat. No.: HY-B1125S
Synonyms: D-Glucosamine-13C6; Chitosamine-13C6
Cat. No.: HY-16781R
CAS No.: 415903-37-6
Synonyms: CJ-023423 (Standard); RQ-00000007 (Standard); AAT-007 (Standard)
Research Areas:
Grapiprant (Standard) is the analytical standard of Grapiprant. This product is intended for research and analytical applications. Grapiprant (CJ-023423) is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2). Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor with IC50 value of 35 nM and Ki value of 24 nM. Grapiprant has the potential for osteoarthritic pain and inflammation treatment .
Cat. No.: HY-P5419
Target:
Research Areas:
Cat. No.: HY-16781S
Synonyms: CJ-023423-d4; RQ-00000007-d4; AAT-007-d4
Cat. No.: HY-W615152
CAS No.: 90-77-7
Target:
CFTR Endogenous Metabolite Reactive Oxygen Species (ROS) HIF/HIF Prolyl-Hydroxylase Autophagy
Research Areas:
2-Amino-2-deoxy-D-glucopyranose is an isomeric form of Glucosamine (HY-B1125). 2-Amino-2-deoxy-D-glucopyranose is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. 2-Amino-2-deoxy-D-glucopyranose also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
