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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
103 Results for "
p40
" in MedChemExpress (MCE) Product Catalog:
Products (103)
103 Results for "p40" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-P7032
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12A; Cytotoxic Lymphocyte Maturation Factor 1, P35; Prev. NKSF1; NK Cell Stimulatory Factor Chain 1; IL-12A; Interleukin-12 Alpha Chain; Interleukin-12 Subunit Alpha; Interleukin 12, P35; CLMF; IL-12, Subunit P35; NFSK; IL35 Subunit; P35; CLMF P35; Interleukin 12A (Natural Killer Cell Stimulatory Factor 1, Cytotoxic Lymphocyte Maturation Factor 1, P35); Natural Killer Cell Stimulatory Factor 1, 35 KD Subunit; Cytotoxic Lymphocyte Maturation Factor 35 KDa Subunit; IL-12 Subunit P35; Interleukin 12A; NF Cell Stimulatory Factor Chain 1; IL12B; Interleukin-12 Subunit Beta; Prev. NKSF2; Interleukin 12, p40; IL-12B; IL12, Subunit p40; CLMF2; IL-12 Subunit p40; NKSF; CLMF p40; CLMF; Cytotoxic Lymphocyte Maturation Factor 2, p40; Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cytotoxic Lymphocyte Maturation Factor 2, p40); Natural Killer Cell Stimulatory Factor-2; Natural Killer Cell Stimulatory Factor, 40 KD Subunit; Truncated Interleukin 12B; Cytotoxic Lymphocyte Maturation Factor 40 KDa Subunit; IMD29; NK Cell Stimulatory Factor Chain 2; IMD28; Interleukin 12B; Interleukin-12 Beta Chain
Species:
Human
Source:
HEK293
1
1
1 Cited Publications
Cat. No.: HY-N3307
CAS No.: 40957-99-1
1
1 Cited Publications
Cat. No.: HY-P7046
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL9; Homolog Of Mouse T Cell And Mast Cell Growth Factor 40; Interleukin 9; p40 T-Cell And Mast Cell Growth Factor; IL-9; Interleukin-9; T-Cell Growth Factor p40; p40 Cytokine; Hp40; Cytokine p40; p40
Species:
Human
Source:
CHO
1
1 Cited Publications
Cat. No.: HY-P75223
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MAPK1; MAPK 2; Prev. PRKM1; ERT1; Prev. PRKM2; Mitogen-Activated Protein Kinase; ERK2; Protein Tyrosine Kinase ERK2; Extracellular Signal-Regulated Kinase 2; MAP Kinase Isoform P42; P41mapk; P42MAPK; MAPK2; MAPK 1; ERK; NS13; Mitogen-Activated Protein Kin
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P99486
CAS No.: 339308-60-0
Synonyms: ABT-874
Target:
Research Areas:
Cat. No.: HY-P990225
Target:
Research Areas:
Cat. No.: HY-N2495
CAS No.: 52250-35-8
Category:
Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Extract Leguminosae/Fabaceae Extract Other Families Extract Other Flavonoids Plant Flavonoids Phenols Polyphenols Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-160231
Target:
Research Areas:
ssRNA42 (sodium) is a 20-mer phosphothioate protected single-stranded RNA oligonucleotide. ssRNA42 (sodium) derives from ssRNA40 by replacement of all G nucleotides with adenosine. ssRNA42 activated human PBMCs to secrete IFN-α, TNF-a, IL- 12p40, and IL-6, but ssRNA42 failed to stimulated murine pDCs and PBMCs.
Synonyms: ME3183; PDE4-IN-14
Research Areas:
Morcamilast (ME3183) is a potent, orally active, selective phosphodiesterase 4 (PDE4) inhibitor, with IC50 values of 1.28 nM, 2.33 nM and 1.63 nM against human PDE4A1A, PDE4B1 and PDE4D2, respectively. Morcamilast inhibits the production of TNF-α, IL-12/23p40, IL-23, IL-17A, IL-4, IL-5 and IL-13 in human PBMCs and T cells, and alleviates chronic Oxazolone (HY-126360)-induced dermatitis, Substance P (HY-P0201)-induced pruritus, Imiquimod (HY-B0180)-induced psoriasis-like dermatitis and LPS (HY-D1056)-induced arthritis . Morcamilast is used for the research of psoriasis, atopic dermatitis, psoriatic arthritis and other inflammatory and immune-related diseases .
Cat. No.: HY-N6250
CAS No.: 136087-29-1
Synonyms: Isomucronulatol 7-O-β-glucoside
Category:
Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Extract Leguminosae/Fabaceae Extract Other Families Extract Plant Flavonoids Monophenols Isoflavanones Phenols Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-171591
CAS No.: 2810810-00-3
Research Areas:
SIK2-IN-4 (Compound 4) is a highly selective SIK1/2 inhibitor (IC50s 0.143 and 0.076 μM, respectively). SIK2-IN-4 reduces the phosphorylation of transcription coactivator 3 (CRTC3) by targeting SIK1/2, thereby regulating cAMP response element binding protein (CREB)-dependent transcriptional activity. SIK2-IN-4 inhibits the production of pro-inflammatory cytokines such as TNF (IC50: 0.11 µM), IL-12/23 p40 (IC50: 0.25 µM), and IL-23 (IC50: 0.47 µM), while inducing the expression of the anti-inflammatory cytokine IL-10. SIK2-IN-4 can be used to study intestinal inflammation and other chronic inflammatory diseases .
Cat. No.: HY-N4061
CAS No.: 1383441-73-3
Target:
Cat. No.: HY-123876
CAS No.: 2171502-44-4
Target:
Research Areas:
AS2677131 is a potent and orally active PIKfyve inhibitor. AS2677131 inhibits f IL-12p40, IL-6 and IL-1β through a PIKfyve-c-Rel pathway. AS2677131 selectively inhibits DNA-binding activity of c-Rel to IL-12p40 and IL-1β promoter. AS2677131 inhibits MHC class II expression on B cells. AS2677131 can be used for the researches of inflammation and immunology, such as arthritis .
Cat. No.: HY-128754R
CAS No.: 111-03-5
Synonyms: MG (18:1) (Standard)
Category:
Cat. No.: HY-177091
CAS No.: 2171506-45-7
Target:
Research Areas:
AS2795440 is a PIKfyve inhibitor. AS2795440 selectively inhibits proinflammatory cytokine such as IL-12p40 and IL-6 production and B cell activation without affecting Ca 2+ signaling. AS2795440 significantly reduces joint inflammation and bone loss in adjuvant-induced arthritis (AIA) mice model. AS2795440 can be used for inflammatory and autoimmune diseases like rheumatoid arthritis, psoriasis and inflammatory bowel disease research .
Cat. No.: HY-P700218AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL9; Homolog Of Mouse T Cell And Mast Cell Growth Factor 40; Interleukin 9; p40 T-Cell And Mast Cell Growth Factor; IL-9; Interleukin-9; T-Cell Growth Factor p40; p40 Cytokine; Hp40; Cytokine p40; p40
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P7083
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL9; Homolog Of Mouse T Cell And Mast Cell Growth Factor 40; Interleukin 9; p40 T-Cell And Mast Cell Growth Factor; IL-9; Interleukin-9; T-Cell Growth Factor p40; p40 Cytokine; Hp40; Cytokine p40; p40
Species:
Mouse
Source:
CHO
Cat. No.: HY-P78319
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL9; Homolog Of Mouse T Cell And Mast Cell Growth Factor 40; Interleukin 9; p40 T-Cell And Mast Cell Growth Factor; IL-9; Interleukin-9; T-Cell Growth Factor p40; p40 Cytokine; Hp40; Cytokine p40; p40
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P701014
Purity: ≥ 95%, as determined by Bis-Tris PAGE. ≥ 95% as determined by HPLC.
Synonyms: IL9; Homolog Of Mouse T Cell And Mast Cell Growth Factor 40; Interleukin 9; p40 T-Cell And Mast Cell Growth Factor; IL-9; Interleukin-9; T-Cell Growth Factor p40; p40 Cytokine; Hp40; Cytokine p40; p40
Species:
Cynomolgus
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
