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1 Cited Publications

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123B9, a tumor-homing agent, is a potent and selective EphA2 agonist with a K_d value of 4.0 μM. 123B9 selectively targets the EphA2 tyrosine kinase receptor ligand-binding domain. 123B9 does not appreciably inhibit the ligand binding domains of the most closely related EphA3 and EphA4 receptors .

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Vidupiprant

Cat. No.: HY-14973

CAS No.: 1169483-24-2

Purity: 98.33%

Synonyms: AMG 853

Target:

Prostaglandin Receptor

Research Areas:

Inflammation/Immunology

Vidupiprant (AMG 853) is a phenylacetic acid derivative. Vidupiprant is a potent and orally active CRTH2 (DP2) and prostanoid D receptor (DP or DP1) dual antagonist with IC₅₀s of 3 nM and 4 nM in buffer, and 8 nM and 35 nM in human plasma, respectively. Vidupiprant has the potential for asthma treatment .

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Penicillin amidase, E. coli (Immobilized)

Cat. No.: HY-P2834

CAS No.: 9014-06-6

Synonyms: PGA

Target:

Biochemical Assay Reagents

Research Areas:

Others

Penicillin amidase, E. coli (Immobilized) (PGA) is an amidohydrolase commonly used in industrial biocatalysis. Penicillin amidase, E. coli (Immobilized) serves as a starting material in the synthesis of semi-synthetic penicillins. Penicillin amidase, E. coli (Immobilized) promotes the production of semi-synthetic β-lactam antibiotics, participates in peptide synthesis, and catalyzes the formation of chiral compounds. Penicillin amidase, E. coli (Immobilized) is regulated by temperature and phenylacetic acid in E. coli. In free E. coli, it participates in the assimilation of aromatic compounds as a carbon source. Penicillin amidase, E. coli (Immobilized) is hypothesized to act as a scavenging enzyme for phenylacetyl-containing compounds in microbial metabolism and is associated with bacterial quorum sensing .

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Phenylacetic acid mustard

Cat. No.: HY-136327

CAS No.: 10477-72-2

Target:

DNA Alkylator/Crosslinker

Research Areas:

Cancer

Phenylacetic acid mustard is the major metabolite of the cancer chemotherapeutic agent Chlorambucil (HY-13593). Chlorambucil is an alkylating agent with antitumor activity .

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2-(4-Chloro-phenoxy)-phenylacetic acid

Cat. No.: HY-20152

CAS No.: 25563-04-6

Target:

Drug Intermediate

Research Areas:

Others

2-(4-Chloro-phenoxy)-phenylacetic acid is a drug intermediate for synthesis of various active compounds.

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Noraramtide

Cat. No.: HY-P10563

CAS No.: 2580150-96-3

Synonyms: BHV-1100

Target:

CD38 IFNAR

Research Areas:

Cancer

Noraramtide (BHV-1100) is an antibody-recruiting molecule. Noraramtide binds to CD38 and recruits natural killer (NK) cells to mediate antibody-dependent cellular cytotoxicity. Noraramtide enhances the capacity of autologous cytokine-induced memory-like (CIML) NK cells to produce IFNγ and CD107a, thereby improving their cytotoxicity against multiple myeloma cells. Noraramtide can be used in the research of multiple myeloma .

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(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-phenylacetic acid

Cat. No.: HY-W013760

CAS No.: 111524-95-9

Target:

Amino Acid Derivatives

Research Areas:

Others

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-phenylacetic acid is a Glycine (HY-Y0966) derivative .

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LS-BF1

Cat. No.: HY-P3350

CAS No.: 2892148-58-0

Target:

Bacterial

Research Areas:

Infection

LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].

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