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7 Results for "

polyamine compound

" in MedChemExpress (MCE) Product Catalog:

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Cyclam

1 Cited Publications

Cat. No.: HY-D0179

CAS No.: 295-37-4

Target:

Biochemical Assay Reagents HIV CXCR

Research Areas:

Cancer

Cyclam is a macrocyclic polyamine that can serve as a high-affinity chelator for Cu²⁺ and a CXCR4-targeting motif. Cyclam is the CXCR4-binding unit of the CXCR4 antagonist Plerixafor (AMD3100) (HY-10046). Cyclam-based macrocyclic compounds possess anti-HIV activity and can mobilize stem cells from the bone marrow. Cyclam can be used in research on ovarian cancer with high CXCR4 expression, as well as in the development of Cu ²⁺ sensors and lanthanide luminescent bioprobes .

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Fluorescent polyamine probe-1

Cat. No.: HY-D1478

CAS No.: 2678634-03-0

Fluorescent polyamine probe-1 (compound 15) is a linear polyamine probe with high uptake efficiency. Fluorescent polyamine probe-1 can be used for the research of transport system into cancer cells .

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FUBP1-IN-2

Cat. No.: HY-151884

CAS No.: 1242862-71-0

Target:

c-Myc

Research Areas:

Cancer

FUBP1-IN-2 (compound 9) is a potent FUBP1 (far upstream binding protein 1) inhibitor. FUBP1-IN-2 inhibits the KH4 FUBP1-FUSE interaction in a gel shift assay. FUBP1-IN-2 binds to FUBP1 in a ChIP assay. FUBP1-IN-2 reduces both c-Myc mRNA and protein expression, increases p21 mRNA and protein expression, and depletes intracellular polyamines .

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N-Benzylethylenediamine

Cat. No.: HY-W010252

CAS No.: 4152-09-4

Target:

Calcium Channel Bacterial

Research Areas:

Infection

N-Benzylethylenediamine is a polyamine compound. N-Benzylethylenediamine can effectively release Ca ²⁺ from the outer membrane of Escherichia coli (ED₅₀: 200-500 μM), but cannot induce TPP ⁺ uptake .

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Trypanothione synthetase-IN-1

Cat. No.: HY-151148

CAS No.: 2355349-41-4

Target:

Parasite

Research Areas:

Infection

Trypanothione synthetase-IN-1 (Compound 1) is a competitive Leishmania infantum trypanothione synthetase (TryS) inhibitor with an IC₅₀ of 14.8 μM when triamine spermidine is as polyamine S .

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Trypanothione synthetase-IN-2

Cat. No.: HY-151150

CAS No.: 3033799-60-6

Target:

Parasite

Research Areas:

Infection

Trypanothione synthetase-IN-2 (Compound 3) is a competitive Leishmania infantum trypanothione synthetase (TryS) inhibitor with an IC₅₀ of 5.4 μM when triamine spermidine is as polyamine S .

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