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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
preeclampsia
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "preeclampsia" in MCE Product Catalog:
90
90 Publications Verification
Cat. No.: HY-18729A
CAS No.: 51298-62-5
Synonyms: NG-Nitroarginine methyl ester hydrochloride
Target:
Research Areas:
L-NAME hydrochloride inhibits NOS with an IC50 of 70 μM. L-NAME is a precursor to NOS inhibitor L-NOARG which has an IC50 value of 1.4 μM. L-NAME hydrochloride requires hydrolysis of the methyl ester by cellular esterases to become a fully functional inhibitor. L-NAME hydrochloride can be used to induce hypertension and preeclampsia models.
1
1 Cited Publications
Synonyms: α-Hydroxybutyric acid
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields Cardiovascular System Disorder
Target:
1
Target:
1
1 Cited Publications
Cat. No.: HY-P10387
1
1 Cited Publications
Cat. No.: HY-P10387A
Target:
Biochemical Assay Reagents COX Interleukin Related NO Synthase Calcium Channel Phospholipase NF-κB
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Magnesium sulfate is a calcium antagonist and a potent L-type calcium channel inhibitor, as well as a tocolytic. Magnesium sulfate has anti-inflammatory, anticonvulsant, vasodilatory, and neuroprotective effects. Magnesium sulfate can be used in the research of diseases such as preeclampsia/eclampsia .
Cat. No.: HY-W094475C
CAS No.: 10034-99-8
Synonyms: Epsom salts, for cell culture
Cat. No.: HY-18729
CAS No.: 50903-99-6
Synonyms: NG-Nitroarginine methyl ester
Target:
Research Areas:
L-NAME inhibits NOS with an IC50 of 70 μM. L-NAME is a precursor to NOS inhibitor L-NOARG which has an IC50 value of 1.4 μM. L-NAME requires hydrolysis of the methyl ester by cellular esterases to become a fully functional inhibitor. L-NAME can be used to induce hypertension and preeclampsia models.
Target:
Research Areas:
Dihydralazine sulfate is an antihypertensive hydrazine derivative and also a low-potency genotoxic agent. Dihydralazine sulfate is a direct-acting mutagen with a mixed gene mutation mechanism, which induces DNA fragmentation in the lung, kidney and spleen of mice, and induces sister chromatid exchange in mouse bone marrow cells. Dihydralazine sulfate specifically kills DNA repair-deficient bacteria. Dihydralazine sulfate is a vasodilator and antihypertensive agent that reduces systemic vascular resistance, increases cardiac output and heart rate, thereby lowering blood pressure. Dihydralazine sulfate can be used in research related to hypertension and severe early-onset preeclampsia .
Target:
Research Areas:
mEH-IN-1 (Compound 62) is a potent microsomal epoxide hydrolase (mEH) inhibitor with the IC50 of 2.2 nM. The mEH is a mammalian α/β-fold hydrolase enzyme, expressed in almost all tissues, hydrolyzes a wide range of epoxide containing molecules. The mEH is mainly localized in the endoplasmic reticulum (ER) of eukaryotic cells. mEH-IN-1 can be used for the research of preeclampsia, hypercholanemia and cancer .
Cat. No.: HY-W012790S
CAS No.: 1219798-97-6
Cat. No.: HY-W094477D
CAS No.: 10034-99-8
Synonyms: Epsom salts, for molecular biology
Cat. No.: HY-W094475D
CAS No.: 10034-99-8
Synonyms: Epsom salts, meets analytical specification of Ph. Eur. BP USP FCC
Cat. No.: HY-W094475E
CAS No.: 10034-99-8
Synonyms: Epsom salts (Pharmaceutical primary standard, USP)
Cat. No.: HY-152014S
CAS No.: 2692624-00-1
Cat. No.: HY-W012790R
CAS No.: 5094-24-6
Cat. No.: HY-174783
Human ACVR2A mRNA encodes the human activin A receptor type 2A (ACVR2A) protein, a member of the TGFB family. ACVR2A mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. It may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality.
Cat. No.: HY-187871
CAS No.: 2854332-29-7
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Endocrinology
Grexenetant (compound I) is a NK-3 receptor antagonist. Grexenetant can be used in the research of diseases mediated by NK-3 receptors, such as depression, anxiety, psychosis, schizophrenia, psychotic disorders, bipolar disorder, cognitive impairment, Parkinson's disease, Alzheimer's disease, attention deficit hyperactivity disorder, pain, convulsions, obesity, inflammatory diseases, vomiting, preeclampsia, airway-related diseases, reproductive disorders, sex hormone-dependent diseases, gynecological diseases, and menopausal syndrome .
Target:
Research Areas:
Dihydralazine sulfate (Standard) is the analytical standard of Dihydralazine sulfate (HY-N7065). This product is intended for research and analytical applications. Dihydralazine sulfate is an antihypertensive hydrazine derivative and also a low-potency genotoxic agent. Dihydralazine sulfate is a direct-acting mutagen with a mixed gene mutation mechanism, which induces DNA fragmentation in the lung, kidney and spleen of mice, and induces sister chromatid exchange in mouse bone marrow cells. Dihydralazine sulfate specifically kills DNA repair-deficient bacteria. Dihydralazine sulfate is a vasodilator and antihypertensive agent that reduces systemic vascular resistance, increases cardiac output and heart rate, thereby lowering blood pressure. Dihydralazine sulfate can be used in research related to hypertension and severe early-onset preeclampsia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
