Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
189 Results for "
primary amide
" in MedChemExpress (MCE) Product Catalog:
Products (189)
189 Results for "primary amide" in MCE Product Catalog:
10
10 Publications Verification
Synonyms: HOSu; 1-Hydroxy-2,5-pyrrolidinedione
2
2 Cited Publications
Target:
Research Areas:
BHQ-1 NHS is a quencher and fluorescent dye. The NHS group activates the carboxyl group on the BHQ-1 molecule, enabling it to react with amino groups (primarily primary amines) on target biomolecules to form stable amide bonds, thereby labeling the biomacromolecules with BHQ-1 .
1
1 Cited Publications
Cat. No.: HY-W591461
DSPE-PEG-COOH, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal carboxylic acid can react with primary amine groups to form a stable amide bond.
1
1 Cited Publications
Cat. No.: HY-W591424
CAS No.: 92451-01-9
Synonyms: mPEG2000-SC; mPEG2000-Succinimidyl ester
Cat. No.: HY-W130610
CAS No.: 124-26-5
Cat. No.: HY-D1085
CAS No.: 216309-02-3
Cat. No.: HY-W1048525
Synonyms: 8-Arm PEG5000-Amine
Target:
Research Areas:
8-Arm PEG5000-NH2 (8-Arm PEG5000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
Cat. No.: HY-W105744
CAS No.: 13108-19-5
Target:
Research Areas:
10-Aminodecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. 10-Aminodecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
Cat. No.: HY-W130610R
CAS No.: 124-26-5
Category:
Target:
Cat. No.: HY-W800839
CAS No.: 2268817-73-6
Target:
Research Areas:
TCO-PEG4-TFP Ester is an amine-reactive labeling reagent used to modify proteins, antibodies, and other amine-containing biopolymers. A 2,3,5,6-tetrafluorophenol (TFP) is a reactive ester that displays much better stability toward hydrolysis in aqueous media resulting in more efficiency and better reproducible labeling of biopolymers. TFP ester of carboxylic acids react with primary amines at the same rate as NHS ester forming covalent amide bond that is identical to one formed by the reaction between primary amines and NHS esters or sulfo-NHS esters.
Cat. No.: HY-W105727
CAS No.: 1120-12-3
Target:
Research Areas:
9-Aminononanoic acid can be used as a PROTAC linker and other conjugation in the synthesis of PROTACs. 9-Aminononanoic acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
Synonyms: Hydroxy-PEG8-acid
Target:
Research Areas:
HO-PEG8-CH2CH2COOH (Hydroxy-PEG8-acid) is a PEG derivative containing a hydroxyl group with a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators to form a stable amide bond .
Cat. No.: HY-W1048519A
Synonyms: 4-Arm PEG10000-amine HCL salt
Cat. No.: HY-W101419
CAS No.: 59512-17-3
Target:
Research Areas:
Ibuprofenamide is a primary amide derived from Ibuprofen (HY-78131) with anti-inflammatory activity. Ibuprofenamide can be used as an intermediate for the preparation of ibuprofenamide derivatives, some of which possess anti-inflammatory, antibacterial, and other activities. Ibuprofenamide can be used in research related to the synthesis of ibuprofenamide derivatives .
Cat. No.: HY-W510032
CAS No.: 1593-55-1
Synonyms: Monoethyl nonanedioate; Ethyl hydrogen azelaate
Target:
Research Areas:
9-Ethoxy-9-oxononanoic acid is a C-11 fatty acid that has an ethyl ester group at the end of the saturated tail. The carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Azelaic Acid Monoethyl Ester has antifungal activity against Cladosporium herbarum.
Cat. No.: HY-D2291
CAS No.: 2671036-80-7
Target:
Research Areas:
BODIPY TMR amide NHS ester is bright, orange fluorescent dye with Ex/Em of 544/570 nm. The NHS ester (or succinimidyl ester) of BODIPY TMR NHS ester is a popular tool for conjugating the dye to a protein or antibody. NHS esters can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
Cat. No.: HY-W591402
CAS No.: 2434639-17-3
Target:
Research Areas:
3,4-Dibromo-Mal-PEG4-acid is a site specific ADC linker with a dibromomaleimide group and an acid group. The dibromomaleimide group allows for two points of substitution due to the two bromine atoms. The carboxylic acid can react with primary amines in the presence of EDC and HATU to form a stable amide bond. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.
Cat. No.: HY-W800846
CAS No.: 1240500-35-9
Target:
Research Areas:
Fmoc-Amido-Tri-(carboxyethoxymethyl)-methane is a multifunctional reagent containing three carboxylic acids and a primary amine that is Fmoc-protected. The carboxylic acids can react with primary amine groups to form stable amide bonds. The Fmoc protecting group can be removed using piperidine, freeing up the amine for a variety of uses such as coupling with carboxylic acids to form amide bonds.
Cat. No.: HY-P1567
CAS No.: 181427-66-7
Target:
Research Areas:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
