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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
57 Results for "
pyridine derivative
" in MedChemExpress (MCE) Product Catalog:
Products (57)
57 Results for "pyridine derivative" in MCE Product Catalog:
8
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2
2 Cited Publications
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CW 008, a derivative of pyrazole-pyridine, is a CREB or PKA pathway agonist. CW 008 also is a stem cell differentiating agent. CW 008 stimulates osteoblast differentiation of human MSCs and increases bone formation in ovariectomized mice. CW008 promotes osteogenesis by activating cAMP/PKA/CREB signaling pathway and inhibiting leptin secretion .
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1 Cited Publications
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Hydronidone is an orally active pyridine derivative. Hydronidone is an inhibitor of phosphodiesterase-4 (PDE4) and cyclo-oxygenase (COX) as well as TGF-β. Hydronidone induces mitochondrial dysfunction and triggers apoptosis. Hydronidone can be used for liver fibrosis, anti-inflammation and anti-cancer study .
Cat. No.: HY-N0682S3
Synonyms: Pyridoxol-13C4 hydrochloride; Vitamin B6-13C4 hydrochloride
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DMF-DMA (N-Dimethoxymethyl-N,N-dimethylamine) is a reagent with both condensation and alkylation functions. DMF-DMA can undergo condensation reactions with active methylene groups or amino groups to generate enamine and imino derivatives, and can also act as an alkylating agent to methylate nitrogen and oxygen atoms in heterocyclic structures. DMF-DMA is widely used in the synthesis of enaminones and dimethylamino imine intermediates, as well as in the construction of heterocyclic backbones such as pyridine, pyrimidine and pyrazole. DMF-DMA can also serve as a polar aprotic co-solvent; although DMF-DMA cannot dissolve cellulose alone, it can form an efficient cellulose dissolution system with diallylimidazolium methoxyacetate .
Cat. No.: HY-32876
CAS No.: 16133-25-8
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Pyridine-3-sulfonyl chloride is a sulfonyl chlorination derivatization reagent for steroidal estrogens. Pyridine-3-sulfonyl chloride reacts with estrogens to form pyridine-3-sulfonyl derivatives, which generate abundant analyte-specific fragment ions upon collision-induced dissociation. Pyridine-3-sulfonyl chloride facilitates quantitative LC-ESI-MS/MS analysis of estrogens in serum and water matrices .
Cat. No.: HY-N0682S1
CAS No.: 5027-82-7
Synonyms: Pyridoxol-d2 hydrochloride; Vitamin B6-d2 hydrochloride
Category:
Alkaloids Plant Aloe africana Extract Other Diseases Pyridine Alkaloids Liliaceae Extract Disease Research Fields
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Cat. No.: HY-N0682S
CAS No.: 1189921-12-7
Synonyms: Pyridoxol-d3 hydrochloride; Vitamin B6-d3 hydrochloride
Cat. No.: HY-W002041
CAS No.: 13325-10-5
Synonyms: 4-Amino-1-butanol
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4-Aminobutan-1-ol (4-Amino-1-butanol) is a linear γ-amino alcohol bearing both a primary amino group and a primary hydroxyl group, which serves as a starting material for the synthesis of pyridine-based Schiff bases. As an important intermediate, 4-Aminobutan-1-ol can be used in the synthesis of GABA derivatives, chiral ligands and other active compounds .
Cat. No.: HY-W009498
CAS No.: 3430-26-0
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Cat. No.: HY-32748
CAS No.: 41404-58-4
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2-Bromo-5-fluoropyridine acts as a bromofluoropyridine starting material and an azaaryl halide coupling partner. 2-Bromo-5-fluoropyridine participates in an oxygen-promoted, ligand-free Pd (OAc)2-catalyzed Suzuki reaction, reacting with arylboronic acids to produce 5-fluoro-2-aryl-substituted pyridine derivatives. 2-Bromo-5-fluoropyridine can be used to synthesize 5-fluoro-2-(4-(methylsulfonyl) phenyl) pyridine, an intermediate of the GPR119 agonist GSK1292263A .
Cat. No.: HY-W003129
CAS No.: 22918-01-0
Cat. No.: HY-32786
CAS No.: 149806-06-4
Cat. No.: HY-69077
CAS No.: 875781-17-2
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5-Bromo-1H-pyrazolo[3,4-b]pyridine is a fused heterocyclic starting material that can be used to synthesize pyrazolo[3,4-b]pyridine-linked sulfonamide derivatives with antibacterial and antioxidant activities. 5-Bromo-1H-pyrazolo[3,4-b]pyridine is applicable to heterocyclic synthesis and research on the development of pyrazolo[3,4-b]pyridine derivatives .
Cat. No.: HY-W002668
CAS No.: 223463-13-6
Cat. No.: HY-W012911
CAS No.: 1513-65-1
2,4-Dihydroxypyridine (compound 2) is a pyridine derivative which is active against both Topo IIKHIV activity and HIV-1 replication, with a pIC50 of 5.05 and 4.07 against Topo IIKHIV and HIV-1 replication, reespectively .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
