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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
rat islet
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "rat islet" in MCE Product Catalog:
7
7 Cited Publications
Synonyms: Arachidonyl trifluoromethyl ketone
Target:
Research Areas:
AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeant trifluoromethyl ketone analog of arachidonic acid. AACOCF3 is a potent and selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2). AACOCF3 blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. AACOCF3 inhibits glucose-induced insulin secretion from isolated rat islets. AACOCF3 has the potential for the research of cardiovascular disease .
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Picolinamide (2-Picolinamide) is an inhibitor of Poly(ADP-ribose) synthetase of nuclei from rat pancreatic islet cells .
Cat. No.: HY-W145482
CAS No.: 13224-94-7
Cat. No.: HY-P5074
CAS No.: 1132745-52-8
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Cat. No.: HY-W039923
CAS No.: 4163-60-4
Cat. No.: HY-P11043
Research Areas:
Cat. No.: HY-103545
CAS No.: 725474-97-5
Synonyms: Gastric inhibitory peptide (1-39) (porcine)
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Cat. No.: HY-P0262
CAS No.: 138579-66-5
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Neurological Disease Metabolic Disease Inflammation/Immunology Endocrinology
Cat. No.: HY-101020R
CAS No.: 1452-77-3
Synonyms: 2-Picolinamide (Standard)
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Picolinamide (Standard) is the analytical standard of Picolinamide. This product is intended for research and analytical applications. Picolinamide (2-Picolinamide) is an inhibitor of Poly(ADP-ribose) synthetase of nuclei from rat pancreatic islet cells .
Cat. No.: HY-120029
CAS No.: 129425-83-8
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Org-9935 is a selective inhibitor of PDE3 with an IC50 of 50 nM. Org-9935 inhibits maturation of oocyte in naturally selected dominant follicle in rhesus macaques. Org-9935 can augment glucose-induced insulin release in isolated rat islets with an EC50 of 20 μM .
Cat. No.: HY-W145482S1
Cat. No.: HY-P77175
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: REG4; Regenerating islet-Derived Protein IV; Regenerating Family Member 4; Regenerating islet-Derived Protein 4; RELP; Regenerating Gene Type IV; GISP; REG-Like Protein; Gastrointestinal Secretory Protein; Reg IV; REG-IV; REG-4; Regenerating islet-Derived
Species:
Rat
Source:
HEK293
Cat. No.: HY-P77174
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: REG4; Regenerating islet-Derived Protein IV; Regenerating Family Member 4; Regenerating islet-Derived Protein 4; RELP; Regenerating Gene Type IV; GISP; REG-Like Protein; Gastrointestinal Secretory Protein; Reg IV; REG-IV; REG-4; Regenerating islet-Derived
Species:
Rat
Source:
HEK293
Cat. No.: HY-P76569
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: REG3A; Proliferation-Inducing Protein 42; Prev. PAP; Reg III-Alpha; PAP1; REG-3-Alpha; HIP; HIP/PAP; REG-III; CDNA FLJ76569, Highly Similar To Homo Sapiens Regenerating islet-Derived 3 Alpha (REG3A), Transcript Variant 1, MRNA; PBCGF; Regenerating islet-D
Species:
Rat
Source:
HEK293
Cat. No.: HY-P76570
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: REG3A; Proliferation-Inducing Protein 42; Prev. PAP; Reg III-Alpha; PAP1; REG-3-Alpha; HIP; HIP/PAP; REG-III; CDNA FLJ76569, Highly Similar To Homo Sapiens Regenerating islet-Derived 3 Alpha (REG3A), Transcript Variant 1, MRNA; PBCGF; Regenerating islet-D
Species:
Rat
Source:
HEK293
Cat. No.: HY-119119
CAS No.: 393834-37-2
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Research Areas:
ATV399 is an inducible nitric oxide synthase (iNOS) inhibitor. ATV399 reduces NO production via allosteric inhibition of iNOS dimerization, thereby protecting rat pancreatic islet β-cells from cytokine-induced mitochondrial stress, endoplasmic reticulum stress, and apoptosis. ATV399 can be used in research related to type 1 diabetes .
Cat. No.: HY-D3174
CAS No.: 2688758-23-6
Cat. No.: HY-188129
CAS No.: 2889348-10-9
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GLP-1R modulator-2 is a GLP-1R positive allosteric modulator with an EC50 of 106 nM. GLP-1R modulator-2 simultaneously binds to the extracellular pocket of GLP-1R and the peptide ligand GLP-1 (9-36) through a molecular glue-like allosteric effect, and selectively enhances GLP-1 (9-36)-induced G protein-dependent cAMP signaling. When used in combination with GLP-1 (9-36) under high-glucose conditions, GLP-1R modulator-2 enhances glucose-dependent insulin secretion in wild-type rat pancreatic islets. GLP-1R modulator-2 exhibits strong probe dependence and significantly potentiates the activity of GLP-1 (9-36). GLP-1R modulator-2 can be used for research on type 2 diabetes and obesity .
Cat. No.: HY-P992574
Research Areas:
Anti-Mouse CD226/DNAM-1 Antibody (480.1) is a rat IgG2a κ isotype blocking monoclonal antibody targeting CD226. Anti-Mouse CD226/DNAM-1 Antibody (480.1) competitively blocks the interaction between CD226 and its ligand CD155, inhibiting CD226-mediated costimulatory signaling. Anti-Mouse CD226/DNAM-1 Antibody (480.1) reduces CD4 + and CD8 + effector T cell proliferation and IFN‑γ secretion, and elevates STAT5 phosphorylation levels in regulatory T cells. Anti-Mouse CD226/DNAM-1 Antibody (480.1) attenuates the severity of insulitis in NOD mice, reduces the risk of type 1 diabetes onset, and decreases infiltration of islet-specific IGRP-reactive CD8 + T cells. Anti-Mouse CD226/DNAM-1 Antibody (480.1) can be used for research on CD226-mediated diseases, such as type 1 diabetes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
