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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
47 Results for "
siderophore
" in MedChemExpress (MCE) Product Catalog:
Products (47)
47 Results for "siderophore" in MCE Product Catalog:
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Cefiderocol (S-649266) is a siderophore cephalosporin which has a potent activity against a broad range of aerobic Gram-negative bacterial species with MIC50s of 2 μg/mL or less.
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1 Cited Publications
Synonyms: Desferrioxamine E; Nocardamin
Cat. No.: HY-160238
CAS No.: 95536-41-7
Synonyms: Corynebactin
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Mal-Deferoxamine is a maleimide-functionalized trihydroxamate siderophore derivative that can be isolated from Streptomyces pilosus. Mal-Deferoxamine possesses highly specific Fe (III) chelating ability, and the stability of complexes formed between it and non-Fe (III) metal ions is significantly lower. Mal-Deferoxamine exhibits growth inhibitory effects against Gram-positive bacteria, but shows no obvious inhibitory activity against Gram-negative bacteria (MIC>50 μM). Mal-Deferoxamine is mainly suitable for scientific research in hematology and related fields .
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Cat. No.: HY-135498
CAS No.: 20008-20-2
Ferrioxamine E is a siderophore and bacterial growth regulator. Ferrioxamine E can chelate ferric iron, and promote the growth, morphological differentiation and antibiotic synthesis of Streptomyces tanashiensis .
Cat. No.: HY-W013673
CAS No.: 1482-97-9
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Cat. No.: HY-N11874
CAS No.: 127902-98-1
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Cat. No.: HY-19882
CAS No.: 941285-15-0
BAL-30072 is a siderophore-bearing monocyclic β-lactam antibiotic with antibacterial activity. BAL-30072 inhibits penicillin-binding proteins 1a, 1b, and 3, thereby disrupting bacterial cell wall synthesis. BAL-30072 inhibits mitochondrial electron transport chain complex II and complex III, while also inhibiting glycolysis and mitochondrial fatty acid β-oxidation. BAL-30072 induces mitochondrial ROS production, cellular ATP depletion, reduces mitochondrial membrane potential, and triggers hepatocyte apoptosis via caspase-3/7 activation. BAL-30072 is a substrate of the hepatic uptake transporters OAT1 and OAT3. BAL-30072 can be used in research related to bacterial infections .
Cat. No.: HY-N13871
CAS No.: 104245-09-2
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Cat. No.: HY-122280R
CAS No.: 26198-65-2
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Cat. No.: HY-122395
CAS No.: 77165-75-4
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Cat. No.: HY-N14935
CAS No.: 70393-50-9
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Cat. No.: HY-129580
CAS No.: 133705-27-8
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Cat. No.: HY-139698
CAS No.: 1401527-90-9
Synonyms: LCB10-0200
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GT-1 (LCB10-0200), a siderophore-linked cephalosporin, is effective against clinical isolates of P. aeruginosa, Klebsiella oxytoca, Proteus spp., Serratia marcescens, and Enterobacter aerogenes.
Cat. No.: HY-N16461
CAS No.: 12676-10-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
