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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
124 Results for "
steroidal compound
" in MedChemExpress (MCE) Product Catalog:
Products (124)
124 Results for "steroidal compound" in MCE Product Catalog:
7
7 Publications Verification
Synonyms: AZD9567
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Research Areas:
Mizacorat (AZD9567; compound 15) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. Exhibits excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation .
7
7 Publications Verification
Cat. No.: HY-18102
CAS No.: 1215085-92-9
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GLPG0492 is an orally active, non-steroidal selective androgen receptor modulator. GLPG0492 exerts functional transactivation by binding to the ligand-binding domain of the receptor, exhibiting preferential partial agonist activity in muscle and bone tissues with low activity in reproductive tissues. GLPG0492 effectively counteracts muscle atrophy-related pathways, significantly enhances muscle strength, maintains motor ability, reduces fibrosis and improves electrophysiological parameters. GLPG0492 prevents immobilization-induced muscle atrophy and regulates muscle mass homeostasis, serving as a valuable tool compound for studies on Duchenne muscular dystrophy, muscle loss and various types of disuse musculoskeletal atrophy .
4
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SAR439859 (compound 43d) is an orally active, non-steroidal, and selective estrogen receptor degrader (SERD). SAR439859 is an effective ER antagonist with ER degradation activity, an EC50 of 0.2 nM. SAR439859 can show potent anti-tumor effects and limited cross-resistance in ER + breast cancer.
1
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Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Etodolac (AY-24236) is a non-steroidal anti-inflammatory compound that can cross the blood-brain barrier and is a non-selective inhibitor of COX (IC50=53.5 nM)
Synonyms: Dihydrocholesterol; 5α-Cholestanol; NSC 18188
Category:
Other disease Other Diseases Disease markers Endogenous metabolite Disease Research Fields Steroids
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Cat. No.: HY-N0386
CAS No.: 61371-55-9
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Cat. No.: HY-B0743A
CAS No.: 52212-02-9
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Pipecuronium bromide is a potent long-acting nondepolarizing steroidal neuromuscular blocking agent (NMBA), and a bisquaternary ammonium compound. Pipecuronium bromide is a powerful competitive nAChR antagonist with a Kd of 3.06 μM .
Cat. No.: HY-N3505
CAS No.: 1111088-89-1
Category:
Dipsacaceae Extract Other Diseases Dipsacus asper Wall. Plants Disease Research Fields Steroids
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Cat. No.: HY-W009347
CAS No.: 20170-32-5
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COX-1-IN-3 (compound 19) is a COX-1 inhibitor with non-steroidal anti-inflammatory activity .
Category:
Other Diseases Veratrum californicum Durand Plants Liliaceae Extract Disease Research Fields Steroids
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Cat. No.: HY-N1375
CAS No.: 84745-94-8
Category:
Asclepiadaceae Extract Monophenols Phenols Cynanchum otophyllum Schneid． Plants Disease Research Fields Cancer Steroids
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CYP11A1-IN-1 (compound 30) is an inhibitor of CYP11A1, with IC50 value of 201-2000 nM. CYP11A1-IN-1 can be used for research in steroid receptor, particularly androgen receptor, dependent diseases and conditions, such as prostate cancer .
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SRD5A1-IN-1 (Compound 4) is a competitive and covalent steroid 5α-reductase type 1 (SRD5A1) inhibitor with an IC50 of 1.44 µM. SRD5A1-IN-1 modulates SRD5A1 function, leading to a lower level of dihydrotestosterone (DHT) production and SRD5A1 protein suppression .
Cat. No.: HY-W102516
CAS No.: 1162-56-7
Synonyms: Δ6-Progesterone
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Cat. No.: HY-B1079
CAS No.: 27470-51-5
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Suxibuzone is a compound used for the study of joint and muscle pain, and it is a prodrug of the non-steroidal anti-inflammatory drug Phenylbutazone.
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Diflorasone diacetate is an anti-inflammatory steroid compound used as locally or topically agent. Diflorasone diacetate is being used for skin disorders to control corticosteroid-responsive dermatoses .
Cat. No.: HY-B2175
CAS No.: 23413-80-1
Synonyms: Aluminum diacetylsalicylate
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Aspirin Aluminum is a novel intermolecular compound which can inhibit gastrointestinal mucosal disorders induced by NSAIDs (non-steroidal anti-inflammatory agents) extracted from patent WO 2010064441 A1.
Synonyms: Dihydrocholesterol-d5; 5α-Cholestanol-d5; NSC 18188-d5
Cat. No.: HY-106566
CAS No.: 66734-13-2
Synonyms: Sch 22219
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Alclometasone dipropionate (Sch 22219) is a steroid compound. Alclometasone dipropionate can be used for the research of dermatitis and skin itch .
Cat. No.: HY-163162
CAS No.: 3029806-33-2
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Anhydro-Ouabain (compound 20) is a cardiotonic steroid which shows anti-inflammatory and neuroprotective activities and thus can be used in neurological research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
