60

Ciprofloxacin hydrochloride monohydrate

60 Cited Publications

Cat. No.: HY-B0356B

CAS No.: 86393-32-0

Synonyms: Bay-09867 hydrochloride monohydrate

Target:

Antibiotic Apoptosis Bacterial Reactive Oxygen Species (ROS) Topoisomerase Mitochondrial Metabolism Akt β-catenin

Research Areas:

Infection Cancer

Ciprofloxacin (Bay-09867) hydrochloride monohydrate is an orally active, blood-brain barrier permeable fluoroquinolone antibacterial agent. Ciprofloxacin hydrochloride monohydrate exerts bactericidal effects primarily by inhibiting topoisomerase II and IV. Ciprofloxacin hydrochloride monohydrate inhibits the proliferation of human dental pulp stem cells and chondrocytes from young rats, and also activates the Akt signaling pathway and upregulates markers such as β-catenin and Nanog to maintain the morphological characteristics of stem cells. Ciprofloxacin hydrochloride monohydrate induces significant neurotoxicity and tissue damage, including reducing serotonin and glutathione levels in the brain, inducing oxidative stress and depression-like behaviors, and causing articular cartilage damage. Ciprofloxacin hydrochloride monohydrate can be applied to research related to infections of necrotic young permanent teeth and neurotoxicity .

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60

Ciprofloxacin monohydrochloride

60 Cited Publications

Cat. No.: HY-B0356A

CAS No.: 93107-08-5

Synonyms: Bay-09867 monohydrochloride

Target:

Antibiotic Apoptosis Bacterial Reactive Oxygen Species (ROS) Topoisomerase Mitochondrial Metabolism Akt β-catenin

Research Areas:

Infection Cancer

Ciprofloxacin (Bay-09867) monohydrochloride is an orally active, blood-brain barrier permeable fluoroquinolone antibacterial agent. Ciprofloxacin monohydrochloride exerts bactericidal effects primarily by inhibiting topoisomerase II and IV. Ciprofloxacin monohydrochloride inhibits the proliferation of human dental pulp stem cells and chondrocytes from young rats, and also activates the Akt signaling pathway and upregulates markers such as β-catenin and Nanog to maintain the morphological characteristics of stem cells. Ciprofloxacin monohydrochloride induces significant neurotoxicity and tissue damage, including reducing serotonin and glutathione levels in the brain, inducing oxidative stress and depression-like behaviors, and causing articular cartilage damage. Ciprofloxacin monohydrochloride can be applied to research related to infections of necrotic young permanent teeth and neurotoxicity .

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60

Ciprofloxacin hydrochloride

60 Cited Publications

Cat. No.: HY-B0356C

CAS No.: 86483-48-9

Synonyms: Bay-09867 hydrochloride

Target:

Antibiotic Apoptosis Bacterial Reactive Oxygen Species (ROS) Topoisomerase Mitochondrial Metabolism Akt β-catenin

Research Areas:

Infection Cancer

Ciprofloxacin hydrochloride (Bay-09867 hydrochloride) is an orally active, blood-brain barrier permeable fluoroquinolone antibacterial agent. Ciprofloxacin hydrochloride exerts bactericidal effects primarily by inhibiting topoisomerase II and IV. Ciprofloxacin hydrochloride inhibits the proliferation of human dental pulp stem cells and chondrocytes from young rats, and also activates the Akt signaling pathway and upregulates markers such as β-catenin and Nanog to maintain the morphological characteristics of stem cells. Ciprofloxacin hydrochloride induces significant neurotoxicity and tissue damage, including reducing serotonin and glutathione levels in the brain, inducing oxidative stress and depression-like behaviors, and causing articular cartilage damage. Ciprofloxacin hydrochloride can be applied to research related to infections of necrotic young permanent teeth and neurotoxicity .

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5

L-Anserine nitrate

5 Cited Publications

Cat. No.: HY-W011393

CAS No.: 10030-52-1

Category:

Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields

Target:

Endogenous Metabolite Parasite

L-Anserine nitrate is a naturally occurring histidine-containing dipeptide that is found in vertebrate skeletal muscle and animal tissues. L-Anserine nitrate serves as a growth-promoting supplement in serum-free HMI-244 medium for bloodstream forms of Trypanosoma brucei and Trypanosoma evansi. L-Anserine nitrate supports the continuous in vitro proliferation of these parasites, and the proliferated parasites retain their morphological characteristics and infectivity to mice. L-Anserine nitrate can be used in studies of African trypanosomiasis .

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3

Tissue and Cell Fixative (4% Paraformaldehyde, PFA)

3 Cited Publications

Cat. No.: HY-DY3003

Tissue and Cell Fixative (4% Paraformaldehyde, PFA) is mainly composed of paraformaldehyde, phosphate, and deionized water, with a pH of 7.0-7.4. Tissue and Cell Fixative (4% Paraformaldehyde, PFA) is suitable for fixing most tissues and cells, and can effectively protect the morphology and structure of tissues and cells as well as nucleic acids.

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