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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
880 Results for "
transmembrane CD20
" in MedChemExpress (MCE) Product Catalog:
Products (880)
880 Results for "transmembrane CD20" in MCE Product Catalog:
132
132 Publications Verification
Target:
Research Areas:
C-176 is a selective and blood-brain barrier permeable STING inhibitor. C-176 covalently targets transmembrane cysteine residue 91 and thereby blocking activation-induced palmitoylation of STING .
56
Research Areas:
Elexacaftor (VX-445, Compound 1) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR). Elexacaftor (VX-445, Compound 1) facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface .
36
36 Cited Publications
V-9302 is a competitive antagonist of transmembrane glutamine flux. V-9302 selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) not ASCT1. V-9302 inhibits ASCT2-mediated glutamine uptake (IC50=9.6 μM) in HEK-293 cells .
36
36 Cited Publications
V-9302 hydrochloride is a competitive antagonist of transmembrane glutamine flux. V-9302 hydrochloride selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) not ASCT1. V-9302 hydrochloride inhibits ASCT2-mediated glutamine uptake (IC50=9.6 µM) in HEK-293 cells .
29
Research Areas:
Glibenclamide (Glyburide) is an orally active ATP-sensitive K + channel (KATP) inhibitor and can be used for the research of diabetes and obesity . Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR) . Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability . Glibenclamide can induce autophagy .
22
22 Cited Publications
Cat. No.: HY-P9913
CAS No.: 174722-31-7
Synonyms: Anti-Human CD20 type I, Chimeric Antibody; HSDB 7455; IDEC-C2B8
Research Areas:
Rituximab is an anti-CD20 chimeric monoclonal antibody used for research of certain autoimmune diseases and cancer.
22
22 Cited Publications
Cat. No.: HY-P9913A
CAS No.: 174722-31-7
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
21
21 Cited Publications
Cat. No.: HY-12326A
CAS No.: 2734909-87-4
Synonyms: Cyclic diadenylate disodium; Cyclic-di-AMP disodium
Target:
21
21 Cited Publications
Cat. No.: HY-12326B
Purity: 99.36%
Synonyms: Cyclic diadenylate diammonium; Cyclic-di-AMP diammonium
Target:
10
7
7
7 Cited Publications
Cat. No.: HY-P0139
CAS No.: 198284-64-9
Target:
Research Areas:
7
Target:
Research Areas:
Vanzacaftor (VX-121) is an orally active noval corrector of Cystic fibrosis transmembrane conductance regulator (CFTR). Vanzacaftor improves processing and trafficking of CFTR protein as well as increases chloride transport in triple combined with Tezacaftor (HY-15448) and Deutivacaftor. Vanzacaftor-Tezacaftor-Deutivacaftor is safe and well tolerated, improving lung function, respiratory symptoms, and CFTR function with cystic fibrosis, which is promising for research in the field of cystic fibrosis diseases .
5
Category:
Natural Products Other disease Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
4
4
4 Cited Publications
Cat. No.: HY-P70700A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: STING1; HSTING; Prev. TMEM173; N-Terminal Methionine-Proline-Tyrosine-Serine Plasma Membrane Tetraspanner; transmembrane Protein 173; Stimulator Of Interferon Response CGAMP Interactor-DeltaC; STING; Stimulator Of Interferon Response CGAMP Interactor-Delt
Species:
Human
Source:
E. coli
3
3 Cited Publications
Target:
Research Areas:
STING-IN-3 is an inhibitor of stimulator of interferon genes (STING). STING-IN-3 efficiently inhibits both hsSTING and mmSTING through covalently target the predicted transmembrane cysteine residue 91 and thereby block the activation-induced palmitoylation of STING .
3
3 Cited Publications
NBI-27914 is a highly selective, high-affinity non-peptide competitive antagonist of human corticotropin-releasing factor receptor 1 (CRFR1). NBI-27914 primarily binds to the His199 and Met276 sites in the transmembrane domain of the receptor .
3
3 Cited Publications
Target:
Research Areas:
T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC) .
3
3 Cited Publications
Cat. No.: HY-P75951
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GPNMB; Glycoprotein Nonmetastatic Melanoma Protein B; Glycoprotein Nmb; Osteoactivin; HGFIN; Hematopoietic Growth Factor Inducible Neurokinin-1; NMB; transmembrane Glycoprotein HGFIN; Glycoprotein (transmembrane) Nmb; Uncharacterized Protein GPNMB; Transm
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
