349 Results for "

urine

" in MedChemExpress (MCE) Product Catalog:
Products (349)

349 Results for "urine" in MCE Product Catalog:

74
74 Publications Verification
Cat. No.: HY-10450
CAS No.: 461432-26-8
Purity:  99.97%
Synonyms: BMS-512148
Target:  

SGLT

Research Areas:  

Metabolic Disease Cancer

Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin induces HIF1 expression and attenuates renal IR injury .
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74
74 Publications Verification
Cat. No.: HY-10450A
CAS No.: 960404-48-2
Purity:  99.97%
Synonyms: BMS-512148 (2S)-1,2-propanediol, hydrate
Target:  

SGLT

Research Areas:  

Metabolic Disease Cancer

Dapagliflozin ((2S)-1,2-propanediol, hydrate) is the S-enantiomer of Dapagliflozin 1,2-propanediol, hydrate. Dapagliflozin ((2S)-1,2-propanediol, hydrate), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin ((2S)-1,2-propanediol, hydrate) induces HIF1 expression and attenuates renal IR injury .
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21
21 Cited Publications
Cat. No.: HY-K0311

MCE GSH/GSSG Assay Kit is suitable for the quantitative determination of reduced and oxidized glutathione (GSH/GSSG) in whole blood, plasma, serum, urine, and tissue and cell extracts.

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12
12 Cited Publications
Cat. No.: HY-153169
CAS No.: 2754428-18-5
Purity:  99.30%
Synonyms: 6PPD-Quinone
6PPD-Q (6PPD-Quinone) is an environmental pollutant that can be detected in human urine and is widely present in the environment. 6PPD-Q targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1, with CNR2 exhibiting the highest binding affinity, potentially acting as a CNR2 receptor agonist to activate cannabinoid receptors. 6PPD-Q induces intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolysis metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation. 6PPD-Q is applicable in research on environmental toxicology, neurodegenerative diseases, and inflammation-related disorders .
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10
10 Cited Publications
Cat. No.: HY-K0319

MCE Lipid Peroxidation (MDA) Assay Kit is suitable for measuring MDA levels in a variety of samples including plasma, serum, urine, tissues or cell lysates.

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6
6 Cited Publications
Cat. No.: HY-B1337
CAS No.: 67-48-1
Choline chloride is an orally active methylxanthine derivative. Choline chloride exhibits weak antihistaminic and anticholinergic activities and potentiates the effects of histamine and acetylcholine. Choline chloride relaxes bronchial smooth muscle, dilates coronary and peripheral blood vessels, increases urine output and electrolyte excretion, stimulates locomotor activity in the central nervous system, and induces transient hypotension following a pressor phase. Choline chloride modulates sleep architecture by increasing wakefulness time and reducing slow-wave sleep, without altering the frequency or severity of nocturnal hypoxemia, apnea, or hypopnea events. Choline chloride is used in studies of bronchospasm, nocturnal asthma, and chronic asthma .
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6
6 Cited Publications
Cat. No.: HY-B1718
CAS No.: 4499-40-5
Synonyms: Oxtriphylline
Choline theophyllinate (Oxtriphylline) is an orally active methylxanthine derivative. Choline theophyllinate exhibits weak antihistaminic and anticholinergic activities and potentiates the effects of histamine and acetylcholine. Choline theophyllinate relaxes bronchial smooth muscle, dilates coronary and peripheral blood vessels, increases urine output and electrolyte excretion, stimulates locomotor activity in the central nervous system, and induces transient hypotension following a pressor phase. It modulates sleep architecture by increasing wakefulness time and reducing slow-wave sleep, without altering the frequency or severity of nocturnal hypoxemia, apnea, or hypopnea events. Choline theophyllinate is used in studies of bronchospasm, nocturnal asthma, and chronic asthma .
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6
6 Cited Publications
Cat. No.: HY-101036
CAS No.: 87-67-2
Purity:  ≥98.0%
Choline bitartrate (Oxtriphylline) is an orally active methylxanthine-derived choline salt of theophylline. Choline bitartrate exhibits weak antihistaminic and anticholinergic activities and can enhance the effects of histamine and acetylcholine. Choline bitartrate relaxes bronchial smooth muscle, dilates coronary and peripheral blood vessels, increases urine output and electrolyte excretion, stimulates central nervous system motor activity, and induces transient hypotension following a pressor phase. Choline bitartrate modulates sleep architecture by increasing wakefulness time and reducing slow-wave sleep, without altering the frequency or severity of nocturnal hypoxemia, apnea, or hypopnea events. Choline bitartrate is used in studies of bronchospasm, nocturnal asthma, and chronic asthma .
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5
5 Cited Publications
Cat. No.: HY-101398
CAS No.: 14643-66-4
Purity:  99.57%
Synonyms: Zincphyrin
Coproporphyrin III (Zincphyrin) is a naturally occurring porphyrin derivative that is mainly found in urine .
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5
5 Cited Publications
Cat. No.: HY-W412175
CAS No.: 68938-73-8
Synonyms: Zincphyrin dihydrochloride
Research Areas:  

Infection

Coproporphyrin III dihydrochloride (Zincphyrin dihydrochlorid) is a naturally occurring porphyrin derivative that is mainly found in urine .
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5
5 Cited Publications
Cat. No.: HY-P72974
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DNASE1; DRNI; Prev. DNL1; Alternative Protein DNASE1; Deoxyribonuclease I; DNase I, Lysosomal; Deoxyribonuclease-1; DNase I; Dornase Alfa; DNAse1; Deoxyribonuclease 1; Human urine Deoxyribonuclease I
Species:  
Human
Source:  
HEK293
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3
3 Cited Publications
Cat. No.: HY-113139
CAS No.: 2140-73-0
Purity:  99.89%
Synonyms: N1-Methylinosine
1-Methylinosine (N1-MetHYlinosine) is a modified nucleotide located at position 37 of eukaryotic tRNA, 3' to the tRNA anticodon. 1-Methylinosine is a minor metabolite of 1-methyladenosine (HY-113081). The level of 1-Methylinosine is significantly elevated in urine samples from breast cancer models .
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3
3 Cited Publications
Cat. No.: HY-B1337S1
CAS No.: 61037-86-3
Choline-d9 chloride is the d9-labeled Choline chloride (HY-B1337). Choline chloride is an orally active methylxanthine derivative. Choline chloride exhibits weak antihistaminic and anticholinergic activities and potentiates the effects of histamine and acetylcholine. Choline chloride relaxes bronchial smooth muscle, dilates coronary and peripheral blood vessels, increases urine output and electrolyte excretion, stimulates locomotor activity in the central nervous system, and induces transient hypotension following a pressor phase. Choline chloride modulates sleep architecture by increasing wakefulness time and reducing slow-wave sleep, without altering the frequency or severity of nocturnal hypoxemia, apnea, or hypopnea events. Choline chloride is used in studies of bronchospasm, nocturnal asthma, and chronic asthma .
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2
2 Cited Publications
Cat. No.: HY-W011552R
CAS No.: 2140-79-6
2'-O-Methyladenosine (Standard) is the analytical standard of 2'-O-Methyladenosine. This product is intended for research and analytical applications. 2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities .
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2
2 Cited Publications
Cat. No.: HY-B0235
CAS No.: 133-67-5
Target:  

Carbonic Anhydrase

Research Areas:  

Metabolic Disease

Trichlormethiazide is an orally active thiazide diuretic, with antihypertensive effect. Trichlormethiazide increases urine volume (UV), Na and K excretion and tends to improve the depressed creatinine clearance (CCRE) in acute renal failure rats model .
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2
2 Cited Publications
Cat. No.: HY-121238
CAS No.: 547-75-1
Purity:  99.46%
Hyocholic Acid is a bile acid found in pig. Hyocholic Acid can also be found in urine samples from patients with cholestasis. Hyocholic Acid promotes GLP-1 secretion via activating TGR5 and inhibiting FXR in enteroendocrine cells. Hyocholic Acid is known for its exceptional resistance to type 2 diabetes .
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2
2 Cited Publications
Cat. No.: HY-W002105
CAS No.: 3238-40-2
2,5-Furandicarboxylic acid is an endogenous metabolite that can be detected in human urine. 2,5-Furandicarboxylic acid serves as an environmentally friendly substitute for terephthalic acid in the production of polyesters. 2,5-Furandicarboxylic acid can be used as the raw material for various chemical intermediates to synthesize polymers, polyurethanes, thermosetting resins, and plasticizers .
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2
2 Cited Publications
Cat. No.: HY-13679
CAS No.: 19767-45-4
Purity:  99.78%
Synonyms: Mesnum
Research Areas:  

Inflammation/Immunology

Sodium 2-mercaptoethanesulfonate (Mesnum) is a thiol-containing urinary tract protective agent and aldehyde scavenger that detoxifies acrolein via its thiol group to form an inert thioether excreted in urine, and competitively inhibits human myeloperoxidase, thereby mitigating Cyclophosphamide (HY-17420)-induced cytogenetic damage. Sodium 2-mercaptoethanesulfonate can be used for research on hemorrhagic cystitis .
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2
2 Cited Publications
Cat. No.: HY-B1337S4
Choline Chloride- 13C3 is the 13C-labeled Choline chloride (HY-B1337). Choline chloride is an orally active methylxanthine derivative. Choline chloride exhibits weak antihistaminic and anticholinergic activities and potentiates the effects of histamine and acetylcholine. Choline chloride relaxes bronchial smooth muscle, dilates coronary and peripheral blood vessels, increases urine output and electrolyte excretion, stimulates locomotor activity in the central nervous system, and induces transient hypotension following a pressor phase. Choline chloride modulates sleep architecture by increasing wakefulness time and reducing slow-wave sleep, without altering the frequency or severity of nocturnal hypoxemia, apnea, or hypopnea events. Choline chloride is used in studies of bronchospasm, nocturnal asthma, and chronic asthma .
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2
2 Cited Publications
Cat. No.: HY-W012722
CAS No.: 816-66-0
Synonyms: α-Ketoisocaproic acid
4-Methyl-2-oxopentanoic acid (α-Ketoisocaproic acid) is a metabolite of L-leucine and is involved in energy metabolism. 4-Methyl-2-oxopentanoic acid increases endoplasmic reticulum stress, promotes lipid accumulation in preadipocytes and insulin resistance by impairing mTOR and autophagy signaling pathways. 4-Methyl-2-oxopentanoic acid also causes oxidative damage, leading to cognitive deficits, inhibits α-ketoglutarate dehydrogenase activity, acts as an oxidative phosphorylation uncoupler and metabolic inhibitor. 4-Methyl-2-oxopentanoic acid acts as a nutrient signal and stimulates skeletal muscle protein synthesis. 4-Methyl-2-oxopentanoic acid can be used in the study of maple syrup urine disease .
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