Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
virions
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "virions" in MCE Product Catalog:
5
5 Cited Publications
Synonyms: SCH-48973; V-073
Target:
Research Areas:
Pocapavir (SCH-48973) is an orally active capsid inhibitor. Pocapavir prevents virion uncoating upon entry into the cell. Pocapavir has antiviral activity against polioviruses. Pocapavir also inhibits enterovirus infections .
4
4 Cited Publications
Synonyms: Adenosyl-Ornithine; A-9145; Antibiotic 32232RP
Research Areas:
Sinefungin is a potent inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication . Sinefungin, a SET7/9 inhibitor, ameliorates renal fibrosis by inhibiting H3K4 methylation .
Cat. No.: HY-159828
CAS No.: 2568911-72-6
Synonyms: VH-499; VH4011499
Dezecapavir (VH-499) is a HIV-1 capsid protein inhibitor. Dezecapavir exhibits picomolar-level antiviral activity against a variety of HIV-1 laboratory strains and clinical isolates in vitro. Dezecapavir inhibits the early and late stages of the HIV-1 life cycle, blocking nuclear import, reverse transcript production, virion assembly, maturation, and post-nuclear import/pre-integration replication processes. Dezecapavir can be used in studies related to HIV-1 infection .
Cat. No.: HY-N13047
CAS No.: 156410-09-2
Category:
Cat. No.: HY-P10310A
Cat. No.: HY-111233
CAS No.: 87495-31-6
Synonyms: WIN-51711
Target:
Research Areas:
Disoxaril (WIN-51711) is an antivirus agent with activity against poliovirus types 1 and 2. Disoxaril inserts into the hydrophobic interior of virus capsid protein VP1 to stabilize virion conformation, inhibits poliovirus uncoating, and prevents viral RNA release and synthesis. Disoxaril can be used for the research of poliovirus infection .
Cat. No.: HY-116282W
CAS No.: 9011-18-1
Synonyms: DSS (MW 6500-10000); DXS (MW 6500-10000)
Cat. No.: HY-W008864
CAS No.: 6291-42-5
Synonyms: β-Octaacetyllactose
Lactose octaacetate (β-Octaacetyllactose) is an Antifungal and antiviral agent. Lactose octaacetate inhibits Aspergillus niger, Penicillium sp., Rhizopus sp., and Fusarium moniliforme. Lactose octaacetate reduces extracellular HSV-1 virions. Lactose octaacetate can be used in research on fungal and viral infections .
Cat. No.: HY-148151
CAS No.: 150132-22-2
(-)-5′-Noraristeromycin is an antiviral agent. (-)-5′-Noraristeromycin also is an enantiomer of 5'-noraristeromycin and can inhibit intracellular HBV replication and virion production. (-)-5′-Noraristeromycin can be used for the research of cancer .
Cat. No.: HY-177638
CAS No.: 141442-28-6
ISIS 1082 is an antisense oligonucleotide targeted to the translation initiation codon of herpes simplex virus (HSV) type 1 and 2 virion capsid protein. It has been shown to inhibit HSV-1 replication in vitro
Cat. No.: HY-172775
CAS No.: 3051872-92-2
Target:
Research Areas:
Spirovirimat (Compound 7) is a potent Monkeypox virus (MPXV) p37 protein inhibitor with an IC50 value of 35 nM. Spirovirimat blocks the formation of extracellular virions by inhibiting viral membrane wrapping. Spirovirimat is promising for research of Monkeypox virus infections .
Cat. No.: HY-P10310
CAS No.: 2305092-66-2
Cat. No.: HY-177638A
ISIS 1082 sodium is an antisense oligonucleotide targeted to the translation initiation codon of herpes simplex virus (HSV) type 1 and 2 virion capsid protein. It has been shown to inhibit HSV-1 replication in vitro
Cat. No.: HY-P5363A
Synonyms: Prostatic acid phosphatase (248-286) acetate
Cat. No.: HY-P5363
Synonyms: Prostatic acid phosphatase (248-286)
Cat. No.: HY-P10653
CAS No.: 811418-15-2
Cat. No.: HY-104074S
Synonyms: SCH-48973-d3; V-073-d3
Cat. No.: HY-124870
CAS No.: 357441-99-7
N.41 is an antiviral agent. N.41 protects APOBEC3G (an antiviral factor) from HIV Vif protein-mediated degradation. N.41 inhibits the Vif-A3G interaction and increases cellular A3G levels and incorporation of A3G into virions, thereby attenuating virus infectivity in a Vif-dependent manner. N.41 inhibits HIV-1 viral replication in PBMCs (IC50: 8.4 μM) .
Cat. No.: HY-120157
CAS No.: 374679-27-3
Vif-ElonginC interaction inhibitor 1 (compound VEC-5) is a potent Vif inhibitor. Vif-ElonginC interaction inhibitor 1 can restrict HIV-1 in Vif-nonpermissive cells. Vif-ElonginC interaction inhibitor 1 can protect A3G, APOBEC3C (A3C), and APOBEC3F (A3F) from Vif-mediated degradation and drastically inhibit Vif function through blocking the interaction between Vif and ElonginC. Vif-ElonginC interaction inhibitor 1 enhances A3G incorporation into HIV-1 virions to reduce viral infectivity .
Cat. No.: HY-173338
CAS No.: 1438403-50-9
Target:
Research Areas:
MSRV-IN-1 (Compound M3) is an inhibitor targeting aquatic rhabdoviruses (such as MSRV, SVCV and IHNV). Its IC50 values for inhibiting MSRV, SVCV and IHNV are 0.92 μM, 2.92 μM and 2.78 μM respectively. MSRV-IN-1 does not act directly on the virions but rather inhibits viral replication by altering the cell cycle arrest state in the S phase induced by the virus and disrupting the viral replication environment. When administered intraperitoneally at a dose of 20 mg/kg, MSRV-IN-1 can significantly increase the survival rate of largemouth bass infected with MSRV by 35.98% and reduce the viral loads in the liver, spleen and kidney. MSRV-IN-1 can be used in the research of diseases related to rhabdoviruses in aquaculture .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
