UNP-6457
UNP-6457 is a selective MDM2 inhibitor (MDM2 IC50 8.9 nM; MDM4 IC50 3.30 μM). UNP-6457 has no anticancer activity against breast cancer.
For research use only. We do not sell to patients.
- CAS No.: 3072696-60-4
- Formula: C62H71F3N14O10
- Molecular Weight:1229.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
MDM2 8.9 nM (IC50) |
MDM4 3.30 μM (IC50) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RS4-11 | IC50 |
50.0 μM
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Viability of human RS4;11 cells assessed as growth inhibition with IC50 >50.0 µM.
Viability of human RS4;11 cells assessed as growth inhibition with IC50 >50.0 µM.
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37312849 |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3072696-60-4
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Molecular Weight 1229.31
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Formula C62H71F3N14O10
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SMILES
O=C(C1=CC=CC=C1)N2[C@@]3([H])C[C@@](NC([C@@H](NC([C@H](CNC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CN4C=C(N=N4)C[C@@H](NC3=O)C(N)=O)=O)C(C)C)=O)CC5=CNC6=CC=CC=C56)=O)CC7=CC=CC=C7)=O)=O)C(C)C)=O)CC8=CC(C(F)(F)F)=CC=C8)=O)([H])C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
UNP-6457 Related Classifications
HY-149988 Related Classifications
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