Azurin p28 peptide
Based on 1 Customer Validation
Azurin p28 peptide is a cell-penetrating peptide derived from the copper-containing oxidoreductase azurin of Pseudomonas aeruginosa, possessing antitumor and anti-angiogenic activities. Azurin p28 peptide can selectively enter tumor cells as a cell-penetrating peptide, block the interaction between COP1 and p53, inhibit p53 degradation, and elevate intracellular p53 protein levels. Azurin p28 peptide can induce tumor cell apoptosis. Azurin p28 peptide can be used in cancer-related research, such as breast cancer and central nervous system tumors.
For research use only. We do not sell to patients.
- Purity : 99.36%
- CAS No.: 897026-25-4
- Formula: C122H197N31O47S2
- Molecular Weight:2914.18
-
Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | IC50 |
23 μM
|
Cytotoxicity against human breast cancer MCF-7 cells assessed as viability reduction by MTT assay.
Cytotoxicity against human breast cancer MCF-7 cells assessed as viability reduction by MTT assay.
|
s10989-022-10386-1 |
| MDA-MB-231 | IC50 |
23 μM
|
Cytotoxicity against human breast cancer MDA-MB-231 cells assessed as viability reduction by MTT assay.
Cytotoxicity against human breast cancer MDA-MB-231 cells assessed as viability reduction by MTT assay.
|
s10989-022-10386-1 |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 897026-25-4
-
Appearance Solid
-
Molecular Weight 2914.18
-
Formula C122H197N31O47S2
-
Color White to off-white
-
Sequence
Leu-Ser-Thr-Ala-Ala-Asp-Met-Gln-Gly-Val-Val-Thr-Asp-Gly-Met-Ala-Ser-Gly-Leu-Asp-Lys-Asp-Tyr-Leu-Lys-Pro-Asp-Asp
-
Sequence Shortening
LSTAADMQGVVTDGMASGLDKDYLKPDD
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (8.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.3431 mL | 1.7157 mL | 3.4315 mL | 8.5787 mL |
| 5 mM | 0.0686 mL | 0.3431 mL | 0.6863 mL | 1.7157 mL |
Azurin p28 peptide Related Classifications
HY-P5910 Related Classifications
Powered by Bioz