Spsb4 - splA/ryanodine receptor domain and SOCS box containing 4 Gene
Also Known as Ssb4; SSB-4; D030068E18Rik
Species: Mus musculus
Summary
Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in several processes, including positive regulation of protein polyubiquitination; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to be located in cytoplasm. Predicted to be part of SCF ubiquitin Ligase complex. Predicted to be active in cytosol. Is expressed in cerebral cortex ventricular layer and cortical plate. Orthologous to human SPSB4 (splA/ryanodine receptor domain and SOCS box containing 4). [provided by Alliance of Genome Resources, Jun 2026]
Biased expression in kidney adult (RPKM 17.5), CNS E11.5 (RPKM 15.9) and 12 other tissues.
Spsb4 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_145134.3 | NP_660116.1 | SPRY domain-containing SOCS box protein 4 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
16369487 | MGI |
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Spsb4 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Cross
|
Spsb4 | Q8R5B6 | PAWR | Homo sapiens | Q96IZ0 | 20561531 | |
|
Cross
|
Spsb4 | Q8R5B6 | PAWR | Homo sapiens | Q96IZ0 | 16369487 |