country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-B2030S

Copy Link Print Information

Propanil-d₅

Name: Propanil-d5
Brand: MedChemExpress
SKU: HY-B2030S
Price: 240.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Propanil-d₅ is the d₅-labeled Propanil (HY-B2030). Propanil is an orally active immunotoxic Herbicide. Propanil causes delayed and sustained loss of CTL lytic function, as well as irreversible impairment of secondary/tertiary CTL responses. Propanil inhibits PHA-induced increases in IL-10, IFN-gamma, IL-2, and intracellular calcium, as well as anti-CD3-induced IL-10 and IFN-gamma release. Propanil induces splenomegaly, thymic atrophy, bone marrow toxicity, and hemoglobin oxidation. Propanil can be used in research on methemoglobinemia and anemia, as well as liver injury.

For research use only. We do not sell to patients.

CAS No.: 1398065-82-1
Formula: C₉H₄D₅Cl₂NO
Molecular Weight:223.11

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Propanil-d₅ Chemical Structure

CAS No.: 1398065-82-1

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Application
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

^[2]^[6]

IL-10

IL-2

All Interleukin Related Isoforms :

All Calcium Channel Isoforms :

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1398065-82-1
Unlabeled CAS 709-98-8
Molecular Weight 223.11
Formula C₉H₄D₅Cl₂NO
SMILES

[2H]C([2H])([2H])C([2H])([2H])C(NC1=CC(Cl)=C(C=C1)Cl)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sheil JM, et al. Propanil exposure induces delayed but sustained abrogation of cell-mediated immunity through direct interference with cytotoxic T-lymphocyte effectors. Environmental health perspectives. 2006 Jul;114(7):1059-64.

[2]. Corsini E, et al. Immunomodulatory effects of the herbicide propanil on cytokine production in humans: In vivo and in vitro exposure. Toxicology and applied pharmacology. 2007 Jul 15;222(2):202-10.

[3]. McMillan DC, et al. Propanil-induced methemoglobinemia and hemoglobin binding in the rat. Toxicology and applied pharmacology. 1990 Sep 15;105(3):503-7.

[4]. Salazar KD, et al. Evidence for a novel endocrine disruptor: the pesticide propanil requires the ovaries and steroid synthesis to enhance humoral immunity. Toxicological sciences : an official journal of the Society of Toxicology. 2006 Sep;93(1):62-74.

[5]. Xie YC, et al. The immunomodulatory effects of the herbicide propanil on murine macrophage interleukin-6 and tumor necrosis factor-alpha production. Toxicology and applied pharmacology. 1997 Jul;145(1):184-91.

[6]. Zhao W, et al. Propanil affects transcriptional and posttranscriptional regulation of IL-2 expression in activated EL-4 cells. Toxicology and applied pharmacology. 1999 Jan 15;154(2):153-9.

[7]. Hong T, et al. Propanil impairs organ development in zebrafish by inducing apoptosis and inhibiting mitochondrial respiration. Journal of hazardous materials. 2024 Dec 05;480:136364.

[8]. Blyler G, et al. Selective myelotoxicity of propanil. Fundamental and applied toxicology : official journal of the Society of Toxicology. 1994 May;22(4):505-10.

[9]. Otuechere CA, et al. Pterocarpus mildbraedii (Harms) extract resolves propanil-induced hepatic injury via repression of inflammatory stress responses in Wistar rats. Journal of food biochemistry. 2020 Dec;44(12):e13506.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote

Amount: USD 0.00

Biological Activity
- Description
- IC₅₀ & Target
- Application
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

Propanil-d₅

All Interleukin Related Isoforms

All Calcium Channel Isoforms