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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
B18
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "B18" in MCE Product Catalog:
2
(-)-Indolactam V is a PKC activator, with Kis of 3.36 nM, 1.03 μM for η-CRD2 (PKCη surrogate peptide), γ-CRD2 (PKCγ surrogate peptide), and Kds of 5.5 nM (η-C1B), 7.7 nM (ε-C1B), 8.3 nM (δ-C1B), 18.9 nM (β-C1A-long), 20.8 nM (α-C1A-long), 137 nM (β-C1B), 138 nM (γ-C1A), 213 nM (γ-C1B), and has antitumor activity.
Cat. No.: HY-P12375
CAS No.: 3027663-77-7
Target:
Research Areas:
B18 peptide is a cationic amphipathic α-helical peptidomimetic that binds to the BST-2 extracellular domain and forms a stable complex through intermolecular hydrogen bonds near the N-terminus. B18 peptide competitively inhibits the binding of BST-2 to the extracellular matrix via its extracellular domain, reducing migrasome formation. B18 peptide induces membrane lysis through the formation of pores/water channels and annular pores, impairing membrane integrity. B18 peptide exhibits anticancer activity against breast cancer. B18 peptide can be used for research on breast cancer .
Cat. No.: HY-N3844
CAS No.: 32507-77-0
Category:
Target:
Cat. No.: HY-155334
CAS No.: 2987900-56-9
RyRs activator 4 (compound B18) is an insect ryanodine receptor activator. RyRs activator 4 has a larvicidal activity of Mythimna separata with an LC50 value of 1.32 mg/L .
Cat. No.: HY-W103245
CAS No.: 14098-24-9
Synonyms: B18C6
Cat. No.: HY-149581
CAS No.: 2906099-98-5
DprE1-IN-9 (compound B18) is an effective reversible DprE1 inhibitor and can bind to the receptor cavity of DprE1. DprE1-IN-9 shows strong antimycobacterial activity not only against non-pathogenic strain H37Ra (MIC=0.18 µg/mL) but also against pathogenic H37Rv and the clinical MDR and XDR isolates .
Cat. No.: HY-155061
CAS No.: 3049656-20-1
Research Areas:
hCYP1B1-IN-1 (compound B18) is a hCYP1B1 inhibitor (IC50=3.6 nM)，as well as an antagonist of Aryl Hydrocarbon Receptor. hCYP1B1-IN-1 exhibtis suitable metabolic stability and good cell-permeability. hCYP1B1-IN-1 inhibits migration of MCF-7 cells .
Cat. No.: HY-177765
CAS No.: 3060504-68-6
Research Areas:
GSPT1 degrader-16 (Compound Lib-B-18J) is a potent and selective cereblon-based molecular glue degrader that targets G1 to S phase transition 1 (GSPT1). GSPT1 degrader-16 shows inhibitory effect to RS4;11, Molt4, and MM.1S cells with IC50 values of 0.002, 0.26 and 0.37 μM. GSPT1 degrader-16 can be used for the research of cancer, such as acute lymphoblastic leukemi .
Cat. No.: HY-N3815
CAS No.: 921211-29-2
Category:
Suregada multiflora (Jussieu) Baillon Terpenoids Diterpenoids Plants Euphorbiaceae Extract
Target:
Cat. No.: HY-P5079
CAS No.: 222557-92-8
Target:
Research Areas:
Cat. No.: HY-172260
Research Areas:
PPO-IN-20 (Compound B18) is a Protoporphyrinogen IX oxidase (PPO, protoporphyrinogen IX oxidase) inhibitor, with a Ki value of 10.3 nM for NtPPO. PPO-IN-20 shows broad-spectrum herbicidal activity and can be used for research in the agricultural field .
Cat. No.: HY-RS09152
Target:
Research Areas:
NDUFB7 Human Pre-designed siRNA Set A contains three designed siRNAs for NDUFB7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P705609
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Pulmonary surfactant-associated protein B; SP-B; 18 kDa pulmonary-surfactant protein; 6 kDa protein; Pulmonary surfactant-associated proteolipid SPL(Phe); SFTPB; SFTP3
Species:
Human
Source:
P. pastoris
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
