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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
143 Results for "
CD40
" in MedChemExpress (MCE) Product Catalog:
Products (143)
143 Results for "CD40" in MCE Product Catalog:
4
4 Cited Publications
Target:
Research Areas:
TRAF-STOP inhibitor 6877002 is a selective CD40-TRAF6 interaction inhibitor. TRAF-STOP inhibitor 6877002 exerts anti-atherosclerotic activity by blocking the CD40-TRAF6 signaling pathway, inhibiting classical monocyte activation, leukocyte recruitment, and macrophage activation and migration. TRAF-STOP inhibitor 6877002 reduces the phosphorylation levels of signaling intermediates in the canonical NF-κB pathway .
3
3 Cited Publications
Target:
Research Areas:
DRI-C21045 (compound 10) is a potent and selective inhibitor of the CD40-CD40L costimulatory protein-protein interaction (PPI) with an IC50 of 0.17 μM. DRI-C21045 shows concentration-dependent inhibition of the activation of NF-κB and B cell proliferation all induced by CD40L with IC50s of 17.1 μM and 4.5 μM, respectively .
2
2 Cited Publications
Cat. No.: HY-P7144
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (Ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor Ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen Ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P72907
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (Ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor Ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen Ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P72908
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (Ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor Ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen Ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P990680
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P990133
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P99742
CAS No.: 2055640-86-1
Synonyms: ADC-1013; JNJ-64457107; Vanalimab
Target:
Research Areas:
1
1 Cited Publications
1
Target:
Research Areas:
Tyrphostin A1(AG9) inhibits CD40L-stimulated IL-12 production in macrophage cultures and antigen-induced generation of Th1 cells.
1
1 Cited Publications
Cat. No.: HY-P99842A
CAS No.: 1416147-64-2
Target:
Research Areas:
Cat. No.: HY-122663A
Purity: 99.88%
Target:
Research Areas:
BIO8898 is a potent CD40-CD154 inhibitor. BIO8898 inhibits soluble CD40L binding to CD40-Ig with an IC50 value of 25 µM. BIO8898 inhibits CD40L-induced apoptosis .
Cat. No.: HY-P99325
CAS No.: 252662-47-8
Synonyms: IDEC-131; Anti-Human CD40 ligand Recombinant Antibody
Target:
Research Areas:
Cat. No.: HY-P99049
CAS No.: 2305607-45-6
Synonyms: APX005M; APX005M; EPI-0050
Target:
Research Areas:
Cat. No.: HY-P99315
CAS No.: 220651-94-5
Synonyms: BG 9588; Anti-Human CD40L Recombinant Antibody; Hu5c8
Target:
Research Areas:
Cat. No.: HY-P99625
CAS No.: 2515463-86-0
Synonyms: SAR441344; INX-021
Target:
Research Areas:
Cat. No.: HY-P99821
CAS No.: 2050816-56-1
Synonyms: ABBV-323
Target:
Research Areas:
Cat. No.: HY-P99321
CAS No.: 299423-37-3
Synonyms: BMS-224819; Chi220; Anti-Human CD40 Recombinant Antibody
Target:
Research Areas:
Teneliximab (BMS-224819) is a chimeric monoclonal antibody, blocks the CD40-CD40L interaction. Teneliximab (BMS-224819) has partial agonist activity resulting in some signaling through CD40 and peripheral B cell depletion .
Cat. No.: HY-P99572
CAS No.: 2253891-70-0
Synonyms: BNT-312; DuoBody-CD40x-4-1BB; GEN1042
Target:
Research Areas:
Cat. No.: HY-P99167
CAS No.: 903512-50-5
Synonyms: HCD122
Target:
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
