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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
DEUP
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "DEUP" in MCE Product Catalog:
Research Areas:
Diethylumbelliferyl phosphate (DEUP) is a broad-spectrum inhibitor of serine esterase and lipases. Diethylumbelliferyl phosphate inhibits cholesteryl ester hydrolase (CEH), adipose triglyceride lipase (ATGL/cytosolic lipase), and retinyl ester hydrolase. Diethylumbelliferyl phosphate blocks the hydrolysis of triglycerides and cholesteryl esters by inhibiting key hydrolases such as CEH and ATGL, thereby inhibiting the mobilization and remodeling of lipid droplet contents, which in turn reduces intracellular reactive oxygen species (ROS) levels and inhibits apoptosis. Diethylumbelliferyl phosphate can be used in research on lipid and cholesterol metabolic diseases and Alzheimer's disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
