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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
DNA chain termination
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "DNA chain termination" in MCE Product Catalog:
Synonyms: (-)-Emtricitabine triphosphate tetrasodium salt
Research Areas:
Emtricitabine triphosphate tetrasodium salt ((-)-Emtricitabine triphosphate tetrasodium salt) is the phosphorylated active metabolite of Emtricitabine (HY-17427). Emtricitabine triphosphate inhibits HIV-1 reverse transcriptase and incorporates into the nascent viral DNA chain, causing chain termination. Emtricitabine triphosphate tetrasodium salt can serve as a biomarker for assessing adherence to antiretroviral therapy. Emtricitabine triphosphate (tetrasodium salt) can be used in research related to HIV infection .
Cat. No.: HY-17422S1
CAS No.: 1185179-33-2
Synonyms: Aciclovir-d4; Acycloguanosine-d4
Cat. No.: HY-131596
CAS No.: 145819-92-7
Synonyms: (-)-Emtricitabine triphosphate
Research Areas:
Emtricitabine triphosphate ((-)-Emtricitabine triphosphate) is the phosphorylated active metabolite of Emtricitabine (HY-17427). Emtricitabine triphosphate inhibits HIV-1 reverse transcriptase and incorporates into the nascent viral DNA chain, causing chain termination. Emtricitabine triphosphate can serve as a biomarker for assessing adherence to antiretroviral therapy. Emtricitabine triphosphate (tetrasodium salt) can be used in research related to HIV infection .
Cat. No.: HY-W1119950
CAS No.: 1644649-86-4
Research Areas:
3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite is an adenine nucleotide monomer precursor used in solid-phase synthesis of oligonucleotides, particularly modified oligonucleotides, such as those with DNA chain end modifications. 3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite, with trityl (Tr), cyanoethyl (CE), and dimethylformamidine (DMF) protecting groups, is a ddNTP adenosine nucleoside useful in applications such as solid-phase oligonucleotide synthesis, probe design, and chain-termination sequencing .
Cat. No.: HY-W784572
CAS No.: 28120-63-0
Synonyms: 3'-O-Acetyl-2'-deoxyadenosine-5'-O-triphosphate
Target:
Research Areas:
3'-O-Acetyl-dATP is an acetylated derivative of dATP (HY-136648). It has been used as a DNA synthesis chain termination reagent in Sanger sequencing.
Cat. No.: HY-W784572A
Synonyms: 3'-O-Acetyl-2'-deoxyadenosine-5'-O-triphosphate sodium
Target:
Research Areas:
3'-O-Acetyl-2'-deoxyadenosine-5'-O-triphosphate (sodium) (3'-O-Acetyl-dATP (sodium)) is an acetylated derivative of the purine nucleotide 2'-deoxyadenosine-5'-triphosphate (HY-136648). 3'-O-Acetyl-2'-deoxyadenosine-5'-O-triphosphate (sodium) can been used as a DNA synthesis chain termination reagent in Sanger sequencing.
Cat. No.: HY-185150
CAS No.: 114088-58-3
Synonyms: 9-(2-Phosphonylmethoxy)ethylguanine
Target:
Research Areas:
PMEG is a nuclear DNA polymerases α, δ, and ε inhibitor that causes DNA chain termination, inhibits DNA synthesis, induces cytotoxicity in dividing cells. PMEG is an acyclic nucleotide phosphonate that forms an active phosphorylated metabolite, PMEG diphosphate, within cells. PMEG has activity against leukemia and melanoma in rodent models. PMEG has poor cell permeability; its prodrug is Rabacfosadine (GS-9219) (HY-13640). PMEG shows antiviral activity against against various DNA virus infections including murine cytomegalovirus (MCMV) and human cytomegalovirus (HCMV). PMEG can be used for the research of non-hodgkin's lymphoma [1][2].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
