1 Result for "

DS21150768

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "DS21150768" in MCE Product Catalog:

Cat. No.: HY-157149
CAS No.: 3074816-62-6
Purity:  99.16%
DS21150768 is an orally active HPK1 inhibitor with an IC50 of 3.27 nM against hHPK1. DS21150768 decreases pSLP76 levels and increases IL-2 levels. DS21150768 shows antitumor effects in multiple syngeneic mouse tumor models, and in combination with anti-PD-1 antibody enhances antitumor efficacy in multiple models. DS21150768 induces immune-related gene signatures in responsive tumor models .
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