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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
Frataxin
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "Frataxin" in MCE Product Catalog:
Cat. No.: HY-W509563
CAS No.: 102616-64-8
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Frataxin-in-1 (Compound (+)-11) is a Frataxin inhibitor with IC50 value of 45 μM, which can be used in the study of Friedreich's ataxia (FRDA) .
Cat. No.: HY-D2047
CAS No.: 1632109-97-7
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ATTO 532 maleimide is a thiol-reactive Fluorescent dye. ATTO 532 maleimide enables site-specific labeling of proteins via maleimide-cysteine chemistry and can be used for single-molecule detection of GroEL EL315C binding/complex formation and single-molecule FRET, and can label surface cysteine substrates, Prothymosin α, Frataxin, and GB1. ATTO 532 maleimide covalently labels Tau, serves as a fluorescence lifetime sensor of amyloid aggregate structural density, and exhibits self-quenching .
Cat. No.: HY-158740
CAS No.: 2644636-20-2
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1(R)-(Trifluoromethyl)oleyl alcohol (compound (R)-24) is a trifluoromethyl alcohol derivative of Oleic acid (HY-N1446) with activity in multiple models of Friedreich ataxia (FRDA). 1(R)-(Trifluoromethyl)oleyl alcohol inhibits ferroptosis induced by Erastin (HY-15763) and decreases lipid peroxidation in NBT human myoblasts with frataxin (FXN) siRNA knockdown. 1(R)-(Trifluoromethyl)oleyl alcohol at 40 μM increases survival to 95% in a model of FRDA where a significant percentage of cell death is caused by FAC (HY-B1645) and BSO (HY-106376) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
