26 Results for "

Metabolomics

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "Metabolomics" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-113266
CAS No.: 40225-14-7
Purity:  ≥95.0%
Valerylcarnitine is an endogenous metabolite, belonging to the short-chain acylcarnitines. Valerylcarnitine acts as a metabolomic biomarker for ionizing radiation exposure in nonhuman primates. Valerylcarnitine can be used for the research of type 1 diabetes .
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1
1 Cited Publications
Cat. No.: HY-113202
CAS No.: 25597-09-5
Purity:  99.91%
Stearoylcarnitine, a fatty ester lipid molecule, is an endogenous metabolite. Stearoylcarnitine can be used as PKC inhibitor. Stearoylcarnitine accumulates in β cells, leading to arrest of insulin synthesis and energy deficiency in type 2 diabetes mouse. Stearoylcarnitine inhibits lecithin cholesterol acyltransferase (LCAT) in rat and rabbits plasma. Stearoylcarnitine acts as a metabolomics biomarker for Parkinson’s disease. Stearoylcarnitine is a less potent inhibitor of GlyT2 .
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1
1 Cited Publications
Cat. No.: HY-W089645
CAS No.: 24589-78-4
Synonyms: N-Methyl-n-trimethylsilyltrifluoroacetamide
Research Areas:  

Cancer

2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide (N-Methyl-n-trimethylsilyltrifluoroacetamide) is an ester product commonly used for silylation reactions in analyticalchemistry. 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide can be used in the derivatization step of metabolomics analysis with gas chromatography/mass spectrometry (GC/MS) or as a derivatization reagent in GC with flame ionization detection analysis. 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide can be used in research for studying Tamoxifen (HY-13757A) resistant breast cancer cells and other disease pathways .
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Cat. No.: HY-W923642
CAS No.: 474923-21-2
Sphingomyelin (d18:1/12:0) is a metabolomic biomarker. Sphingomyelin (d18:1/12:0) exhibits favorable diagnostic properties and may facilitate the early detection and targeted prevention of dyslipidemia-related adverse cardiovascular events .
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Cat. No.: HY-100978
CAS No.: 6920-35-0
Purity:  ≥98.0%
Synonyms: DL-Hexanoylcarnitine chloride
(±)-Hexanoylcarnitine chloride is a fatty acid metabolite that breaks down fatty acids into energy that can be used by the body. (±)-Hexanoylcarnitine chloride also serves as a specific and easily detectable biomarker for rat skeletal muscle toxicity. Cerivastatin (HY-129458) and TMPD (HY-W012145) induce an increase in Hexanoylcarnitine in rats in a metabolomic analysis of the rectus femoris muscle. In type 2 diabetes, Hexanoylcarnitine is also significantly associated with and improves prediction of all-cause mortality. Hexanoylcarnitine is a biomarker for the identification of novel pathogenic pathways .
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Cat. No.: HY-N11604
CAS No.: 204983-72-2
Synonyms: C16(Plasm)-16:1-PC; PC(P-16:0/16:1); PlsC 16:0/16:1
1-(1(Z)-Hexadecenyl)-2-palmitoleoyl-sn-glycero-3-phosphocholine [PC (P-16:0/16:1 (9Z))] is a phosphatidylcholine that can be utilized for liposome preparation and serves as a marker in metabolomics research .
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Cat. No.: HY-W704079
CAS No.: 22610-61-3
Synonyms: ​MG(18:0/0:0/0:0); L-(+)-1-Monostearin; 1-Octadecanoyl-sn-glycerol
Target:  

Endogenous Metabolite

Research Areas:  

Cardiovascular Disease

1-Stearoyl-sn-glycerol is (MG(18:0/0:0/0:0); L-(+)-1-Monostearin; 1-Octadecanoyl-sn-glycerol) is a monoglyceride and also a metabolite found in plasma, which can be used in metabolomic analysis of plasma for coronary artery lesions (CAL) .
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Cat. No.: HY-W047324
CAS No.: 34213-86-0
Synonyms: 4-Aminophenylmannoside, 98%
Research Areas:  

Others

4-Aminophenyl-α-D-mannopyranoside, 98% is a mannopyranoside. 4-Aminophenyl-α-D-mannopyranoside, 98%, after conjugation to the surface of liposomes, can enhance delivery to the mouse brain via GLUT1- and GLUT3-mediated transport. 4-Aminophenyl-α-D-mannopyranoside, 98% can be detected as a characteristic glycoside in the metabolomics of fermented foods and is considered a potential health-related metabolic marker. 4-Aminophenyl-α-D-mannopyranoside, 98% can be used in studies of glycosylation processes and enzyme-substrate interactions .
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Cat. No.: HY-113202S
CAS No.: 1021439-31-5
Stearoyl-L-carnitine-d3 is the deuterium labeled Stearoylcarnitine. Stearoylcarnitine, a fatty ester lipid molecule, is an endogenous metabolite. Stearoylcarnitine can be used as PKC inhibitor. Stearoylcarnitine accumulates in β cells, leading to arrest of insulin synthesis and energy deficiency in type 2 diabetes mouse. Stearoylcarnitine inhibits lecithin cholesterol acyltransferase (LCAT) in rat and rabbits plasma. Stearoylcarnitine acts as a metabolomics biomarker for Parkinson’s disease. Stearoylcarnitine is a less potent inhibitor of GlyT2 .
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Cat. No.: HY-152014S
CAS No.: 2692624-00-1
Stearoylcarnitine-d3-1 (hydrochloride) is deuterium labeled Stearoylcarnitine. Stearoylcarnitine, a fatty ester lipid molecule, is a human endogenous metabolite. Stearoylcarnitine acts as a metabolomics biomarker for early-onset-preeclampsia and late-onset-preeclampsia .
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Cat. No.: HY-113266R
CAS No.: 40225-14-7
Valerylcarnitine (Standard) is the analytical standard of Valerylcarnitine. Valerylcarnitine is an endogenous metabolite, belonging to the short-chain acylcarnitines. Valerylcarnitine acts as a metabolomic biomarker for ionizing radiation exposure in nonhuman primates. Valerylcarnitine can be used for the research of type 1 diabetes .
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Cat. No.: HY-113266S
CAS No.: 2847775-89-5
Synonyms: C5:0 L-carnitine-d9
Valerylcarnitine-d9 (C5:0 L-carnitine-d9) is the deuterium labeled Valerylcarnitine (HY-113266). Valerylcarnitine is an endogenous metabolite, belonging to the short-chain acylcarnitines. Valerylcarnitine acts as a metabolomic biomarker for ionizing radiation exposure in nonhuman primates. Valerylcarnitine can be used for the research of type 1 diabetes .
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Cat. No.: HY-152922
CAS No.: 204983-73-3
Synonyms: C16(plasm)-18:2-PC; ​1-1(Z)-Hexadecenyl-2-Linoleoyl-sn-glycero-3-PC; PC(P-16:0/18:2)
Research Areas:  

Others

1-(1(Z)-Hexadecenyl)-2-linoleoyl-sn-glycero-3-phosphocholine (C16(plasm)-18:2-PC; 1-1(Z)-Hexadecenyl-2-Linoleoyl-sn-glycero-3-PC; PC(P-16:0/18:2)) is a phosphatidylcholine, which can be used in lipid preparations and as a marker in metabolomic research .
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Cat. No.: HY-113202S1
CAS No.: 2936622-19-2
Stearoyl-L-carnitine-d9 chloride is the deuterium labeled Stearoyl-L-carnitine chloride. Stearoyl-L-carnitine chloride, a fatty ester lipid molecule, is an endogenous metabolite. Stearoyl-L-carnitine chloride can be used as PKC inhibitor. Stearoyl-L-carnitine chloride accumulates in β cells, leading to arrest of insulin synthesis and energy deficiency in type 2 diabetes mouse. Stearoyl-L-carnitine chloride inhibits lecithin cholesterol acyltransferase (LCAT) in rat and rabbits plasma. Stearoyl-L-carnitine chloride acts as a metabolomics biomarker for Parkinson’s disease. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2 .
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Cat. No.: HY-L207
661 compounds

Metabolomics is the large-scale study of cellular metabolic complement, with proven utility in both basic and applied studies of plants, microorganisms, and mammals. As an important tool for the study of complex biological systems, metabolomics monitors the complex molecular networks that exist in the natural flow of information from genes to mRNA and proteins to organisms. The metabolome is composed of biomolecules that most closely resemble the phenotype of an organism, and changes in its composition can easily lead to the production of diseases. Therefore, metabolomics has received much attention in drug target discovery, drug response and translational research of disease mechanisms. Mass spectrometry-based metabolomics methods can simultaneously detect and quantify thousands of metabolite signatures, thereby characterizing the pathophysiological mechanisms of various biomedical symptoms.

MCE can provide 661 mass spectrometry human endogenous metabolites that can be used for metabolite identification and quantification, functional cell detection and phenotypic screening of mass spectrometry.

Cat. No.: HY-L240
45 compounds

Plant hormones are natural signaling molecules synthesized by plants themselves, serving as crucial chemical messengers that exert physiological effects on plants at extremely low concentrations. They coordinate cellular growth, division, differentiation, and organ formation, helping plants adapt to environmental changes. Major categories include abscisic acid, auxins, gibberellins, cytokinins, ethylene, and brassinosteroids, among others.

MCE has included 45 plant hormones, which can be used for identification in plant metabolomics and related botanical research.

Cat. No.: HY-L215
6,106 compounds

Metabolomics, positioned as the systemic characterization of small-molecule metabolites within biological systems, has emerged as an indispensable analytical platform in both fundamental research and translational applications across plant sciences, microbial biotechnology, and biomedical investigations. Functioning as a critical component in multi-omics integration, this discipline deciphers the intricate molecular networks operating downstream of genomic, transcriptomic, and proteomic regulation, thereby capturing the dynamic biochemical phenotype closest to organismal functionality. The metabolome, comprising endogenous compounds with molecular weights typically below 1500 Da, serves as the functional readout of cellular processes and environmental interactions, where perturbations in metabolic networks are frequently implicated in disease pathogenesis. Such unique attributes have propelled metabolomics into a pivotal role in pharmacological research, particularly in target deconvolution, pharmacodynamic assessment, and mechanistic elucidation of pathological processes.

MCE can provide 6,106 mass spectrometry human metabolites that can be used for metabolite identification and quantification, functional cell detection and phenotypic screening of mass spectrometry.

Cat. No.: HY-L262
4,460 compounds

Natural products are small-molecule compounds produced in nature, derived from animals, plants, and microorganisms, including both primary and secondary metabolites. With their structural diversity and favorable biological activities, natural products have long been an important source for drug discovery. Traditional natural product research has often focused on isolating single active components, whereas metabolomics emphasizes a holistic approach—comprehensively detecting all metabolites in a sample and systematically capturing both known and unknown constituents. Consequently, mass spectrometry‑based metabolomics databases have become a key technological support for screening known components and identifying unknown compounds from natural sources.

MCE Mass Spectrometry Natural Product Library contains 4,460 natural products, covering multiple structural classes, including sugars and glycosides, phenylpropanoids, quinones, flavonoids, terpenoids, etc. All compounds have undergone rigorous quality control by LC/MS and other analytical methods, and can serve as high‑purity reference standards for metabolite identification.

Cat. No.: HY-W747074
CAS No.: 71781-66-3
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Tauroursodeoxycholic acid-3-sulfate disodium is a taurine-conjugated 3-sulfated bile acid that belongs to endogenous sulfated bile acid metabolites and is detectable in human and animal serum, urine, bile, and metabolomics panels. Tauroursodeoxycholic acid-3-sulfate disodium occurs at higher concentrations in the gallbladder of hibernating snakes of the five-paced pit viper species than in active snakes. Tauroursodeoxycholic acid-3-sulfate disodium can serve as a biochemical indicator in research related to hepatobiliary diseases .
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Cat. No.: HY-N22048
CAS No.: 1354722-74-9
Synonyms: LysoPE(0:0/20:5)
Lysophosphatidylethanolamine (20:5) (LysoPE (0:0/20:5)) is a lysophosphatidylethanolamine containing a 20:5 acyl chain . Lysophosphatidylethanolamine (20:5) competitively binds to site 1 and site 2 of human serum albumin (HSA), with Ki values of 13.77 μM and 4.02 μM, respectively. Lysophosphatidylethanolamine (20:5) is elevated in Doxorubicin hydrochloride (HY-15142)-induced cardiotoxicity and is reduced by BP1. Lysophosphatidylethanolamine (20:5) is useful for metabolomics and biomarker studies of cardiomyopathy, type 2 diabetes insulin resistance, and obesity .
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