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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
54 Results for "
Mg2+
" in MedChemExpress (MCE) Product Catalog:
Products (54)
54 Results for "Mg2+" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P75979
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPM1A; Protein Phosphatase 1A (Formerly 2C), Magnesium-Dependent, Alpha Isoform; Protein Phosphatase, Mg2+/Mn2+ Dependent 1A; Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A; Protein Phosphatase 1A; Protein Phosphatase 2C, Alpha Isoform; PP2Calpha; Alternati
Species:
Mouse
Source:
E. coli
Cat. No.: HY-126220
CAS No.: 1372642-77-7
Target:
Research Areas:
KMG-301AM is the acetoxy methyl esterified form of KMG-301. KMG-301AM successfully accumulates in mitochondria and then it is hydrolyzed to KMG-301. KMG-301 is an Mg 2+-selective fluorescent probe functional in mitochondria in intact cells. Since the mitochondrial membrane is impermeable to KMG-301, it is not released upon depolarization of the mitochondrial membrane potential. KMG-301 can indicate changes in mitochondrial Mg2+ concentration and shows Mg 2+ transport across the mitochondrial membrane in the early phases of a cellular model .
Target:
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KMG-301AM TFA is the acetoxy methyl esterified form of KMG-301. KMG-301AM TFA successfully accumulates in mitochondria and then it is hydrolyzed to KMG-301. KMG-301 is an Mg 2+-selective fluorescent probe functional in mitochondria in intact cells. Since the mitochondrial membrane is impermeable to KMG-301, it is not released upon depolarization of the mitochondrial membrane potential. KMG-301 can indicate changes in mitochondrial Mg2+ concentration and shows Mg 2+ transport across the mitochondrial membrane in the early phases of a cellular model .
Cat. No.: HY-164220
CAS No.: 2919466-30-9
Target:
Research Areas:
PPM1A-IN-1 (Compound IV-4) is an inhibitor for PP2C Ser/Thr phosphatase protein phosphatase Mg2+/Mn2+-dependent 1A. PPM1A-IN-1 exhibits antibacterial activity against Mycobacterium tuberculosis .
Cat. No.: HY-173084
Target:
Research Areas:
BRD6257 is an orally active inhibitor for protein phosphatase, Mg2+/Mn2+ dependent 1D PPM1D with an IC50 of 5 nM. BRD6257 activates p53 signaling pathway with an EC50 of 51 nM, increases the p21 expression, inhibits the proliferation of cancer cell MOLM13 (IC50=2.8 μM). BRD6257 exhibits good metabolic stability in human and rat liver microsomes .
Cat. No.: HY-D0157
CAS No.: 321859-11-4
Cat. No.: HY-RS08847
Target:
Research Areas:
MUC7 Human Pre-designed siRNA Set A contains three designed siRNAs for MUC7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-120459
CAS No.: 110230-95-0
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Rs-029 is an inhibitor Na+/K+ ATPase and an activator for Mg2+ ATPase. Rs-029 decreases the ATP level in red blood cells .
Cat. No.: HY-157998
CAS No.: 2760515-88-4
mG2N001 is a negative allosteric modulator (NAM) (IC50: 93 nM) of the metabotropic glutamate receptor mGluR2 and binds to mGluR2 as an antagonist (Ki: 63 nM). mG2N001 is microparticle- and plasma-stable, and its radioisotope [11C]mG2N001 can be used in PET imaging. [11C]mG2N001 has good brain heterogeneity and brain penetration, and can selectively accumulate in mGluR2-rich regions, producing high-contrast brain images .
Cat. No.: HY-138035
CAS No.: 53823-15-7
Tenellin is a fungal metabolite that has been found in Beauveria. It inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in equine erythrocytes by 51, 57, and 74%, respectively, when used at a concentration of 200 μg/mL.1 Tenellin is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of- 4.84 and 11.95 μM, respectively.
Cat. No.: HY-RS08244
Target:
Research Areas:
MCOLN1 Human Pre-designed siRNA Set A contains three designed siRNAs for MCOLN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P86974
Synonyms: MCLN1_HUMAN antibody; Mcoln 1 antibody; Mcoln1 antibody; Mg 2 antibody; Mg-2 antibody; Mg2 antibody; ML 4 antibody; ML4 antibody; MLIV antibody; MST080 antibody; MCLN1_HUMAN antibody; Mcoln 1 antibody; Mcoln1 antibody; Mg 2 antibody; Mg-2 antibody; Mg2 antibody; ML 4 antibody; ML4 antibody; MLIV antibody; MST080 antibody; MSTP080 antibody; Mucolipidin antibody; Mucolipin 1 antibody; Mucolipin-1 antibody; Mucolipin1 antibody; TRP ML1 antibody; TRPML1 antibody;
Cat. No.: HY-P702374
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MCOLN1; Transient Receptor Potential Mucolipin 1; Mucolipin TRP Cation Channel 1; Mucolipin 1; TRPML1; Mucolipidin; ML4; Mucolipin-1; TRPM-L1; Mg-2; MSTP080; ML1; MST080; Mucolipidosis Type IV Protein; MLIV; Mucolipidosis Type IV; Transient Receptor Poten
Species:
Human
Source:
E. coli Cell-free
Cat. No.: HY-P701383
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MCOLN1; Transient Receptor Potential Mucolipin 1; Mucolipin TRP Cation Channel 1; Mucolipin 1; TRPML1; Mucolipidin; ML4; Mucolipin-1; TRPM-L1; Mg-2; MSTP080; ML1; MST080; Mucolipidosis Type IV Protein; MLIV; Mucolipidosis Type IV; Transient Receptor Poten
Species:
Human
Source:
HEK293
Cat. No.: HY-E71619
Target:
Research Areas:
2-Phosphosulfolactate phosphatase (EC 3.1.3.71) requires Mg2+.
Cat. No.: HY-E71136
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Research Areas:
(S)-β-Bisabolene synthase (EC 4.2.3.55) requires Mg2+ or Mn2+ for activity.
Cat. No.: HY-E71065
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(2Z,6E)-Farnesyl diphosphate synthaserequires Mg2+ or Mn2+ for activity.
Cat. No.: HY-E71670
Target:
Research Areas:
3-Dehydro-L-gulonate-6-phosphate decarboxylase (EC 4.1.1.85) requires Mg2+.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
