40 Results for "

Microbes

" in MedChemExpress (MCE) Product Catalog:
Products (40)

40 Results for "Microbes" in MCE Product Catalog:

13
Trimethylamine N-oxide
Trimethylamine N-oxide
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13 Publications Verification
Cat. No.: HY-116084
CAS No.: 1184-78-7
Purity:  ≥98.0%
Category:  

Cardiovascular Disease Natural Products Other disease Endogenous metabolite Disease markers Microorganism Disease Research Fields Inflammation/Immunology Lung Cancer Markers Cancer

Target:  

Drug Metabolite NOD-like Receptor (NLR) Reactive Oxygen Species (ROS) TGF-beta/Smad Endogenous Metabolite

Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway .
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13
Trimethylamine N-oxide dihydrate
Trimethylamine N-oxide dihydrate
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13 Publications Verification
Cat. No.: HY-108915
CAS No.: 62637-93-8
Purity:  ≥98.0%
Category:  

Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

NOD-like Receptor (NLR) Reactive Oxygen Species (ROS) TGF-beta/Smad Endogenous Metabolite

Trimethylamine N-oxide dihydrate is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide dihydrate induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide dihydrate also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway .
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7
Betaine
Betaine
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7 Cited Publications
Cat. No.: HY-B0710
CAS No.: 107-43-7
Synonyms: Trimethylglycine; carboxy-N,N,N-trimethylmethanaminium
Category:  

Natural Products Metabolic Disease Other Families Extract Endogenous metabolite Plant Animal Disease markers Microorganism Disease Research Fields Lung Cancer Markers Cancer

Target:  

Environmental Pollutants Endogenous Metabolite

Betaine (Trimethylglycine) is a natural compound found in many foods and also an active methyl-donor which can maintain normal DNA methylation patterns [1,2]. Betaine is found ubiquitously in plants, animals, microorganisms, and rich dietary sources including seafood, spinach, and wheat bran. Betaine also acts as an osmolyte, to maintain the avian’s cellular water and ion balance to improve the avian’s capacity against heat stress via preventing dehydration and osmotic inactivation. It helps in maintaining the protective osmolytic activity, especially in heat-stressed birds. Betaine may promote various intestinal microbes against osmotic variations and thus improve microbial fermentation activity .
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7
Saponins
Saponins
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7 Cited Publications
Cat. No.: HY-100597
CAS No.: 8047-15-2
Purity:  98.36%
Synonyms: Saponin
Category:  

Triterpenes Plant Terpenoids Camellia sinensis (L.) O. Ktze. Extract Disease Research Fields Inflammation/Immunology Theaceae Extract

Target:  

Environmental Pollutants Bacterial Fungal

Saponins (Saponin) is a class of chemical compound of glycosides found in particular abundance in various plant species. In plants, Saponins may serve as anti-feedants, and to protect the plant against microbes and fungi .
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3
Shikimic acid
Shikimic acid
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3 Cited Publications
Cat. No.: HY-N0130
CAS No.: 138-59-0
Category:  

Plant Ketones, Aldehydes, Acids Other Diseases Artemisia absinthium Extract Compositae/Asteraceae Extract Microorganism Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Shikimic acid is a key metabolic intermediate of the aromatic amino acid biosynthesis pathway, found in microbes and plants.
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1
Trimethylamine N-oxide-d9
Trimethylamine N-oxide-d9
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1 Cited Publications
Cat. No.: HY-116084S
CAS No.: 1161070-49-0
Purity:  99.76%
Trimethylamine N-oxide-d9 is the deuterium labeled Trimethylamine N-oxide. Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway .
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1
PBP10
PBP10
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1 Cited Publications
Cat. No.: HY-P1116
CAS No.: 794466-43-6
Target:  

Bacterial Reactive Oxygen Species (ROS) Interleukin Related

Research Areas:  

Infection Inflammation/Immunology

PBP10 is a decapeptide. PBP10 selectively binds to lipoteichoic acid (LTA), lipopolysaccharide (LPS) and phosphatidylinositol-4,5-bisphosphate (PIP2). PBP10 penetrates cell membranes and possesses bactericidal, anti-inflammatory, cell motility-inhibiting and actin assembly-regulating activities. PBP10 is applicable to relevant research on bacterial infections, microbe-induced inflammation, skin and soft tissue infections, as well as sepsis .
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1
PBP10 TFA
PBP10 TFA
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1 Cited Publications
Cat. No.: HY-P1116A
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

PBP10 TFA is a decapeptide. PBP10 TFA selectively binds to lipoteichoic acid (LTA), lipopolysaccharide (LPS) and phosphatidylinositol-4,5-bisphosphate (PIP2). PBP10 TFA penetrates cell membranes and possesses bactericidal, anti-inflammatory, cell motility-inhibiting and actin assembly-regulating activities. PBP10 TFA is applicable to relevant research on bacterial infections, microbe-induced inflammation, skin and soft tissue infections, as well as sepsis .
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1
(-)-Fucose (Standard)
(-)-Fucose (Standard)
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1 Cited Publications
Cat. No.: HY-N1480R
CAS No.: 2438-80-4
Synonyms: 6-Desoxygalactose (Standard); L-(-)-Fucose (Standard); L-Galactomethylose (Standard)
Category:  

Human Gut Microbiota Metabolites Natural Products Microorganism Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite Parasite

(-)-Fucose (Standard) is the analytical standard of (-)-Fucose. This product is intended for research and analytical applications. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions. (-)-Fucose is orally active, inhibits CL11-induced inflammatory response in kidney and tumor growth .
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(-)-Fucose
(-)-Fucose
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Cat. No.: HY-N1480
CAS No.: 2438-80-4
Synonyms: 6-Desoxygalactose; L-(-)-Fucose; L-Galactomethylose
Category:  

Human Gut Microbiota Metabolites Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides Monosaccharides

Target:  

Endogenous Metabolite Parasite

(-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions. (-)-Fucose is orally active, inhibits CL11-induced inflammatory response in kidney and tumor growth .
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Actinine
Actinine
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Cat. No.: HY-113270
CAS No.: 407-64-7
Synonyms: γ-Butyrobetaine; Deoxycarnitine
Category:  

Natural Products Marine algae Marine natural products Microorganism Endogenous metabolite

Target:  

Endogenous Metabolite

Actinine is a metabolic and pro-atherogenic intermediate with oral activity. Actinine acts as a substrate for the yeaW/X microbial enzyme complex to generate trimethylamine (TMA). Actinine accelerates atherosclerosis development in a gut microbe-dependent manner. Actinine can be used for the research of atherosclerosis .
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Diethyl phosphate
Diethyl phosphate
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Cat. No.: HY-101417
CAS No.: 598-02-7
Purity:  ≥98.0%
Synonyms: Diethyl phosphoric acid
Category:  

Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Interleukin Related

Diethylphosphate (Diethyl phosphoric acid) is an orally active organophosphorus pesticides metabolite. Diethylphosphate can interfere with thyroid hormone-related mechanisms and affect intestinal microbes in rats .
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2-Methylvaleric acid
2-Methylvaleric acid
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Cat. No.: HY-W010516
CAS No.: 97-61-0
Synonyms: 2-Methylpentanoic acid
Category:  

Plant Ketones, Aldehydes, Acids Metabolic Disease Other Families Extract Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

2-Methylvaleric acid is a branched short-chain fatty acid (SCFA) produced by the metabolism of branched-chain amino acids by gut microbes. 2-Methylvaleric acid can be used as a potential biomarker for metabolic diseases such as type 2 diabetes, and its content is significantly reduced in the feces of diabetic mice. 2-Methylvaleric acid may regulate host energy metabolism and inflammatory response through G protein-coupled receptors (GPCRs) or histone deacetylase (HDAC) inhibition. 2-Methylvaleric acid can be used to study gut microbe-host interactions and metabolic diseases as a fecal biomarker[1][2].
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(R)-Leucic acid
(R)-Leucic acid
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Cat. No.: HY-30216
CAS No.: 20312-37-2
Synonyms: D-α-Hydroxyisocaproic acid
Category:  

Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Amino Acid Derivatives Endogenous Metabolite

(R)-Leucic acid (D-α-Hydroxyisocaproic acid) is an orally active D-isomer of the α-hydroxy analogue of Leucine (HY-N0486). (R)-Leucic acid is a metabolite of Lactobacillus and can promote intestinal fatty acid absorption by upregulating CD36 expression. (R)-Leucic acid can be used to study microbe-host interactions and the regulation of lipid metabolism by probiotics .
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Antiarol
Antiarol
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Cat. No.: HY-W016289
CAS No.: 642-71-7
Synonyms: 3,4,5-Trimethoxyphenol
Category:  

Plant Monophenols Cochlospermum vitifolium Extract Other Diseases Phenols Other Families Extract Disease Research Fields Bixaceae Extract

Target:  

Endogenous Metabolite

Antiarol (3,4,5-Trimethoxyphenol) is a phenolic compound present in the trunk of Coffea canephora. Antiarol is a metabolite produced by chicken cecal microbes, whose cecal content changes dynamically with the severity of wooden breast (WB; a muscle disease prevalent in broilers) and enters the plasma through circulation .
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Shikimic acid (Standard)
Shikimic acid (Standard)
0 Images
Cat. No.: HY-N0130R
CAS No.: 138-59-0
Category:  

Plant Ketones, Aldehydes, Acids Artemisia absinthium Extract Compositae/Asteraceae Extract Microorganism Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite

Shikimic acid (Standard) is the analytical standard of Shikimic acid. This product is intended for research and analytical applications. Shikimic acid is a key metabolic intermediate of the aromatic amino acid biosynthesis pathway, found in microbes and plants.
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Caffeic acid-13C3
Caffeic acid-13C3
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Cat. No.: HY-N0172S
CAS No.: 1185245-82-2
Synonyms: 3,4-Dihydroxycinnamic acid-13C3
Caffeic acid- 13C3 is an 13C labeled caffeic acid. Caffeic acid is a phytonutrient belonging to the flavonoids. Caffeic acid and its derivatives, are potential antimicrobial agents, chronic infection induced by microbes such as bacteria, fungi, and viruses .
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Betaine (Standard)
Betaine (Standard)
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Cat. No.: HY-B0710R
CAS No.: 107-43-7
Synonyms: Trimethylglycine (Standard); carboxy-N,N,N-trimethylmethanaminium (Standard)
Category:  

Natural Products Plant Animal Disease markers Other Families Extract Microorganism Endogenous metabolite Lung Cancer Markers Cancer

Target:  

Endogenous Metabolite Reference Standards

Betaine (Standard) is the analytical standard of Betaine. This product is intended for research and analytical applications. Betaine (Trimethylglycine) is a natural compound found in many foods and also an active methyl-donor which can maintain normal DNA methylation patterns [1,2]. Betaine is found ubiquitously in plants, animals, microorganisms, and rich dietary sources including seafood, spinach, and wheat bran. Betaine also acts as an osmolyte, to maintain the avian’s cellular water and ion balance to improve the avian’s capacity against heat stress via preventing dehydration and osmotic inactivation. It helps in maintaining the protective osmolytic activity, especially in heat-stressed birds. Betaine may promote various intestinal microbes against osmotic variations and thus improve microbial fermentation activity .
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Diethyl phosphate-d10-1
Diethyl phosphate-d10-1
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Cat. No.: HY-101417S1
CAS No.: 2483831-48-5
Purity:  99.70%
Synonyms: Diethyl phosphoric acid-d10
Diethyl phosphate-d10-1 is the deuterium labeled Diethyl phosphate. Diethylphosphate (Diethyl phosphoric acid) is an orally active organophosphorus pesticides metabolite. Diethylphosphate can interfere with thyroid hormone-related mechanisms and affect intestinal microbes in rats .
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Trimethylamine-N-oxide-13C3
Trimethylamine-N-oxide-13C3
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Cat. No.: HY-116084S1
CAS No.: 2413127-00-9
Trimethylamine-N-oxide- 13C3 is the 13C-labeled Trimethylamine N-oxide. Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway .
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