124 Results for "

Microbial metabolite

" in MedChemExpress (MCE) Product Catalog:
Products (124)

124 Results for "Microbial metabolite" in MCE Product Catalog:

50
Urolithin A
Urolithin A
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50 Publications Verification
Cat. No.: HY-100599
CAS No.: 1143-70-0
Purity:  99.82%
Category:  

Human Gut Microbiota Metabolites Microorganisms Monophenols Anti-aging Phenols Polyphenols Endogenous metabolite Disease Research Fields Cancer

Target:  

Drug Metabolite Reactive Oxygen Species (ROS) DNA/RNA Synthesis Autophagy Apoptosis Endogenous Metabolite

Urolithin A, a gut-microbial metabolite of ellagic acid, exerts anti-inflammatory, antiproliferative, and antioxidant properties. Urolithin A induces autophagy and apoptosis, suppresses cell cycle progression, and inhibits DNA synthesis .
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Resolvin D2
Resolvin D2
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5 Cited Publications
Cat. No.: HY-121636
CAS No.: 810668-37-2
Purity:  99.90%
Synonyms: RvD2
Target:  

TRP Channel

Research Areas:  

Infection Neurological Disease Inflammation/Immunology

Resolvin D2 is a metabolite of docosahexaenoic acid (DHA), with anti-inflammatory, anti-infective activities. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Resolvin D2 is a remarkably potent inhibitor of TRPV1 (IC50 = 0.1 nM) and TRPA1 (IC50 = 2 nM) in primary sensory neurons .
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5
Urolithin C
Urolithin C
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5 Cited Publications
Cat. No.: HY-135897
CAS No.: 165393-06-6
Purity:  ≥98.0%
Category:  

Metabolic Disease Phenols Polyphenols Endogenous metabolite Disease Research Fields

Target:  

Calcium Channel Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite

Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is a L-type Ca 2+ channel opener and enhances Ca 2+ influx. Urolithin C induces cell apoptosis through a mitochondria-mediated pathway and also stimulates reactive oxygen species (ROS) formation .
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4
Itaconic acid
Itaconic acid
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4 Cited Publications
Cat. No.: HY-Y0520
CAS No.: 97-65-4
Synonyms: Methylenesuccinic acid
Category:  

Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Endogenous Metabolite Ferroptosis

Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors. Itaconic acid has anti-inflammatory, anti-microbial and immunomodulatory effect .
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3
Phenylacetylglutamine
Phenylacetylglutamine
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3 Cited Publications
Cat. No.: HY-W050026
CAS No.: 28047-15-6
Synonyms: NSC 203800; Phenylacetyl-L-glutamine
Category:  

Human Gut Microbiota Metabolites Microorganisms Other disease Other Diseases Disease markers Amino acids Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Phenylacetylglutamine is a colonic microbial metabolite from amino acid fermentation.
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3
Desaminotyrosine
Desaminotyrosine
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3 Cited Publications
Cat. No.: HY-W015346
CAS No.: 501-97-3
Synonyms: 3-(4-Hydroxyphenyl)propionic acid
Category:  

Infection Microorganisms Monophenols Ketones, Aldehydes, Acids Phenols Endogenous metabolite Disease Research Fields

Target:  

Influenza Virus Endogenous Metabolite

Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.
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2
Dihydrocaffeic acid
Dihydrocaffeic acid
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2 Cited Publications
Cat. No.: HY-N2406
CAS No.: 1078-61-1
Synonyms: 3,4-Dihydroxy-benzenepropanoic acid
Category:  

Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Phenols Polyphenols Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

p38 MAPK Endogenous Metabolite Reactive Oxygen Species (ROS) NO Synthase

Dihydrocaffeic acid is a microbial metabolite of flavonoids. Dihydrocaffeic acid scavenges intracellular ROS and increases nitric oxide synthase activity. Dihydrocaffeic acid reduces phosphorylation of MAPK p38 and prevent UVB-induced skin damage. Dihydrocaffeic acid has antioxidant, anti-inflammatory and anti-cartilage degradation activities .
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2
Direct Black 38
Direct Black 38
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2 Cited Publications
Cat. No.: HY-D0256
CAS No.: 1937-37-7
Synonyms: Chlorazol Black E; Ferristatin II disodium; C.I. 30235
Direct Black 38 (Chlorazol Black E) is a benzidine-based azo dye, a substrate of Enterococcus gallinarum, and is mainly used for textile dyeing. Direct Black 38 is biodegradable after being reduced by microbial enzymes (such as Enterococcus gallinarum azoreductase), breaking the azo bonds and releasing benzidine and 4-aminobiphenyl. Direct Black 38 can be used in environmental toxicology, wastewater treatment and carcinogenicity studies, but its metabolite benzidine is listed as a human carcinogen .
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2
Phenylacetylglutamine-d5
Phenylacetylglutamine-d5
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2 Cited Publications
Cat. No.: HY-W050026S
CAS No.: 1331909-01-3
Synonyms: NSC 203800-d5; Phenylacetyl-L-glutamine-d5
Phenylacetylglutamine-d5 (NSC 203800-d5) is the deuterium labeled Phenylacetylglutamine (HY-W050026). Phenylacetylglutamine is a colonic microbial metabolite from amino acid fermentation .
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2
Ilimaquinone
Ilimaquinone
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2 Cited Publications
Cat. No.: HY-119500
CAS No.: 71678-03-0
Purity:  ≥98.0%
Category:  

Infection Quinones Animals Marine natural products Benzene Quinones Sponge Disease Research Fields Inflammation/Immunology Cancer

Target:  

HIV Bacterial

Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathway. Ilimaquinone can induce vesiculation of the Golgi apparatus . Ilimaquinone exerts anti-HIV, anti-microbial, anti-inflammatory, and effects .
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1
Phenylacetylglycine
Phenylacetylglycine
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1 Cited Publications
Cat. No.: HY-W015061
CAS No.: 500-98-1
Category:  

Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Adrenergic Receptor Apoptosis Endogenous Metabolite

Phenylacetylglycine is a gut microbial metabolite that can activate β2AR. Phenylacetylglycine protects against cardiac injury caused by ischemia/reperfusion .
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Oosporein
Oosporein
0 Images
1 Cited Publications
Cat. No.: HY-N7719
CAS No.: 475-54-7
Category:  

Quinones Microorganisms Other Diseases Benzene Quinones Disease Research Fields

Target:  

Endogenous Metabolite Bacterial Fungal Parasite Apoptosis Reactive Oxygen Species (ROS) Caspase HSV

Oosporein is a microbial metabolite and a red crystalline toxin produced by various fungi. Oosporein can promote the reproduction of fungi in host bodies by inhibiting insect immunity, and possesses multiple activities such as antibacterial, antiviral (HSV), and insecticidal effects. Oosporein can inhibit plant growth. In addition, Oosporein can also induce apoptosis, cell membrane damage, oxidative stress, and mitochondrial damage. Oosporein has certain antitumor activity .
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Quercetin 5-O-β-D-glucopyranoside
Quercetin 5-O-β-D-glucopyranoside
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1 Cited Publications
Cat. No.: HY-N13015
CAS No.: 34199-21-8
Category:  

Flavonols Flavonoids Animals

Target:  

Endogenous Metabolite

Quercetin 5-O-β-D-glucopyranoside is a glycosylated flavonoid metabolite and flavonoid compound. Quercetin 5-O-β-D-glucopyranoside can be produced by microbial transformation of Quercetin (HY-18085) via Mucor hiemalis. Quercetin 5-O-β-D-glucopyranoside can be used in studies related to benign prostatic hyperplasia .
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N-Acetylputrescine hydrochloride
N-Acetylputrescine hydrochloride
0 Images
1 Cited Publications
Cat. No.: HY-113100
CAS No.: 18233-70-0
Purity:  ≥99.0%
Category:  

Natural Products Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

N-Acetylputrescine hydrochloride is a polyamine metabolite that regulates cell proliferation and signal transduction mainly by participating in polyamine acetylation modification. N-Acetylputrescine hydrochloride may reduce the positive charge of polyamines, affect protein-nucleic acid interactions, and promote cell growth. The concentration changes of N-Acetylputrescine hydrochloride can help disease diagnosis (such as early screening and efficacy evaluation of lung cancer) and microbial cell wall structure research. N-Acetylputrescine hydrochloride can be used as a potential biomarker for the progression of squamous cell carcinoma of the lung (SCCL) and Parkinson's disease (PD) .
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N-Acetylputrescine
N-Acetylputrescine
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1 Cited Publications
Cat. No.: HY-W342604
CAS No.: 5699-41-2
Synonyms: NAP
Category:  

Alkaloids Human Gut Microbiota Metabolites Neurological Disease Other Alkaloids Endogenous metabolite Disease Research Fields Cancer

Target:  

Endogenous Metabolite

N-Acetylputrescine is a polyamine metabolite that regulates cell proliferation and signal transduction mainly by participating in polyamine acetylation modification. N-Acetylputrescine may reduce the positive charge of polyamines, affect protein-nucleic acid interactions, and promote cell growth. The concentration changes of N-Acetylputrescine can help disease diagnosis (such as early screening and efficacy evaluation of lung cancer) and microbial cell wall structure research. N-Acetylputrescine can be used as a potential biomarker for the progression of squamous cell carcinoma of the lung (SCCL) and Parkinson's disease (PD) .
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2,6-Diaminoheptanedioic acid
2,6-Diaminoheptanedioic acid
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Cat. No.: HY-128746
CAS No.: 583-93-7
Purity:  99.96%
Category:  

Microorganisms Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

2,6-Diaminopimelic acid is a endogenous metabolite produced in bacteria and is a component of cell wall. 2,6-Diaminopimelic acid is essential for microbial metabolism and is a potential marker for quantification of microbial proteins .
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Phosphoramidon disodium
Phosphoramidon disodium
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Cat. No.: HY-N2021A
CAS No.: 164204-38-0
Category:  

Cardiovascular Disease Alkaloids Microorganisms Disease Research Fields Cancer Indole Alkaloids

Target:  

MMP Angiotensin-converting Enzyme (ACE) Neprilysin Endogenous Metabolite

Phosphoramidon disodium, a microbial metabolite, is a specific metalloprotease thermolysin inhibitor with an IC50 of 0.4 μg/mL. Phosphoramidon disodium also inhibits endothelin-converting enzyme (ECE), neutral endopeptidase (NEP), and angiotensin-converting enzyme (ACE) with IC50 values of 3.5, 0.034, and 78 μM, respectively .
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2,2-Dihydroxyacetic acid
2,2-Dihydroxyacetic acid
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Cat. No.: HY-W019724
CAS No.: 563-96-2
Category:  

Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Drug Intermediate Reactive Oxygen Species (ROS)

2,2-Dihydroxyacetic acid is an endogenous metabolite, which is the monohydrate of Glyoxylic Acid. 2,2-Dihydroxyacetic acid may participate in the microbial glyoxylate cycle, induce an increase in reactive oxygen species, promote cell differentiation, and modify proteins to form advanced glycation end products (AGEs) (HY-NP165). 2,2-Dihydroxyacetic acid is associated with metabolic diseases such as primary hyperoxaluria .
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3-Epideoxycholic acid
3-Epideoxycholic acid
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Cat. No.: HY-48814
CAS No.: 570-63-8
Target:  

Bacterial FXR

Research Areas:  

Infection Inflammation/Immunology

3-Epideoxycholic acid is a secondary bile acid and a microbial metabolite of Deoxycholic acid (HY-N0593). 3-Epideoxycholic acid targets FXR in dendritic cells, reduces their immunostimulatory properties, promotes the generation of Treg cells, and exerts anti-inflammatory activity. 3-Epideoxycholic acid can promote the growth of the bacterium Bacteroides. 3-Epideoxycholic acid can be used in research related to inflammatory and immune diseases as well as bacterial infections .
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(2S)-Isoxanthohumol
(2S)-Isoxanthohumol
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Cat. No.: HY-N2584
CAS No.: 70872-29-6
Category:  

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