Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
Mitochondrial dynamics
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "Mitochondrial dynamics" in MCE Product Catalog:
Cat. No.: HY-W452285
CAS No.: 14777-17-4
Target:
Cat. No.: HY-123583
CAS No.: 1644119-76-5
Target:
Research Areas:
MitoBADY is a mitochondria-selective Raman probe that successfully visualizes mitochondria in live HeLa cells at a concentration of 200-400 nM for 10 minutes. MitoBADY can be utilized for the study of mitochondrial dynamics .
Cat. No.: HY-174148
Target:
Research Areas:
Anion transporter-4 (Compound 6) is a small-molecule anion transporter, which induces tubulin degradation and mitochondrial dysfunction. Anion transporter-4 can increase intracellular anion levels such as chloride ions by disrupting microtubule dynamics, promoting lipid peroxidation, and impairing mitochondrial function. Anion transporter-4 triggers ferroptosis to exert anticancer activity. Anion transporter-4 is promising for research of cancers .
Cat. No.: HY-189689
CAS No.: 3020765-79-8
Target:
Research Areas:
WX-02-16 is a BAX inhibitor. WX-02-16 covalently and stereoselectively modifies BAX C126, restricting BAX conformational dynamics and blocking BAX activation and mitochondrial cytochrome c release. WX-02-16 protects Bak-deficient cells from apoptosis (apoptosis). WX-02-16 protects primary sensory neurons from apoptosis, improving survival and reducing caspase-3/7 activity. WX-02-16 can be used in research on various diseases and injuries triggered by BAX-dependent cell death .
Cat. No.: HY-W800535
CAS No.: 480-26-2
Cat. No.: HY-190479
CAS No.: 3093414-52-6
Target:
Research Areas:
Tubulin polymerization-IN-98 prodrug-1 is a prodrug prepared with the tubulin polymerization inhibitor A‑8d as the parent compound. Tubulin polymerization-IN-98 prodrug-1 binds to the colchicine binding site, and palladium-loaded resin catalyzes the efficient release of the active parent, thereby disrupting tubulin polymerization and dynamics. Tubulin polymerization-IN-98 prodrug-1 combined with palladium-loaded resin induces G2/M phase arrest, apoptosis, collapse of mitochondrial membrane potential, excessive ROS production, and inhibits endothelial cell migration and tube formation. Tubulin polymerization-IN-98 prodrug-1 combined with palladium-loaded resin achieves tumor growth inhibition in a HepG2 xenograft tumor-bearing mouse model. Tubulin polymerization-IN-98 prodrug-1 can be used for research related to hepatocellular carcinoma .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
