3 Results for "

NIC-11

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "NIC-11" in MCE Product Catalog:

NIC-12
NIC-12
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Cat. No.: HY-158093
CAS No.: 2409826-23-7
Target:  

NOD-like Receptor (NLR)

Research Areas:  

Inflammation/Immunology

NIC-12 is a potent NLRP3 inhibitor. NIC-12 selectively reduces circulating IL-1ß levels in the LPS-endotoxemia mice model. NIC-12 inhibits NLRP3 inflammasome activation in mouse macrophages .
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Nic-15
Nic-15
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Cat. No.: HY-159577
CAS No.: 2896739-91-4
Target:  

PI3K mTOR Akt

Research Areas:  

Cancer

Nic-15 (compound 4n) is an anti-constrictive agent used to antagonize the hypovascularity of pancreatic tumors. The hypovascularity allows cancer cells to adapt to the nutrient-deficient tumor microenvironment and develop drug resistance. Nic-15 can regulate the PI3K/Akt/mTOR pathway and alleviate ER stress induced by Gemcitabine (HY-17026). Nic-15 can significantly inhibit the migration and colony formation of MIA PaCa-2 and PANC-1 pancreatic cancer cells. The combination of Nic-15 and Gemcitabine can effectively solve the problem of pancreatic tumor resistance. In an in vivo xenograft model, Nic-15 can significantly enhance the efficacy of Gemcitabine .
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Nicandrenone
Nicandrenone
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Cat. No.: HY-N17739
CAS No.: 40071-64-5
Synonyms: NIC-1
Category:  

Tetracyclic Triterpenoids Terpenoids Plants 500 - Internal Server Error | MedChemExpress

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