Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
NSC10010
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "NSC10010" in MCE Product Catalog:
NSC10010 hydrochloride is a Mycobacterium tuberculosis ClpC1 inhibitor and differentiation inducer (IC50 = 4 µM; Kd = 2.8 µM). NSC10010 hydrochloride inhibits the ATPase and proteolytic activities of ClpC1 by binding to it, and downregulates E2F1, induces DNA damage, apoptosis, and lipid droplet accumulation, thereby inhibiting breast cancer cell proliferation and Mycobacterium tuberculosis H37Rv growth. NSC10010 hydrochloride can be used for research on breast cancer and tuberculosis .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
