4 Results for "

Protectin D1

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Protectin D1" in MCE Product Catalog:

Cat. No.: HY-130413
CAS No.: 660430-03-5
Synonyms: NeuroProtectin D1; NPD1
Protectin D1, a neuroprotectin D1 produced by neuronal cells, is a member of a newly discovered family of bioactive products derived from docosahexaenoic acid. Protectin D1 also serves as a specialized pro-resolving mediator, exhibiting effective in vivo pro-resolving activity in various human disease models. Additionally, Protectin D1 is an inhibitor of NALP3 inflammasomes and regulates the PI3K/AKT and HIF-1α signaling pathways. Protectin D1 exerts anti-inflammatory effects by reducing ROS levels, inhibiting the expression of NALP3, ASC, and Caspase-1, and consequently decreasing the release of pro-inflammatory cytokines IL-1β and IL-18. Furthermore, Protectin D1 enhances miRNA-210 expression, activates the PI3K/AKT signaling pathway, and exerts cardioprotective effects. Protectin D1 holds promise for research in cardiovascular diseases and inflammatory disorders .
loading...
    loading...
Cat. No.: HY-149551
CAS No.: 1365694-03-6
Synonyms: 17-epi-Protectin D1
Research Areas:  

Inflammation/Immunology

17(R)-Protectin D1 (17-epi-Protectin D1) is a protectin-family-specific pro-resolving lipid mediator derived from DHA (HY-B2167) and generated via Aspirin (HY-14654) triggering, possessing pro-inflammatory resolution, neuroprotective, and other activities. 17(R)-Protectin D1 is also the 17R-epimer of Protectin D1 (HY-130413). 17(R)-Protectin D1 enhances macrophage phagocytosis of Escherichia coli and limits neutrophil infiltration. 17(R)-Protectin D1 attenuates stroke severity in animal models. 17(R)-Protectin D1 can be used in research related to peritonitis and stroke .
loading...
    loading...
Cat. No.: HY-165645
Synonyms: Neuopotecti D1-d5; NPD1-d5; PD1-d5
Protectin D1-d5 (Neuopotecti D1-d5) is deuterium labeled Protectin D1 .
loading...
    loading...
Cat. No.: HY-170645
CAS No.: 934005-36-4
Target:  

Drug Intermediate

Research Areas:  

Neurological Disease

Neuroprotectin D1 methyl ester is an esterified form of Protectin D1 (HY-130413). Neuroprotectin D1 methyl ester is an intermediate in the synthesis of Protectin D1.
loading...
    loading...