Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
SR4077
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "SR4077" in MCE Product Catalog:
Cat. No.: HY-Y1624
CAS No.: 10465-81-3
Synonyms: ADDP; SR 4077
Target:
Research Areas:
1,1'-(Azodicarbonyl)-dipiperidine (ADDP; SR 4077) is an oxidizing reagent for intracellular reducing agents and a chemical coupling reagent. 1,1'-(Azodicarbonyl)-dipiperidine exhibits biological activities such as pro-oxidation, radiosensitization, and induction of apoptosis, and can serve as a Mitsunobu reaction catalyst for chemical synthesis. 1,1'-(Azodicarbonyl)-dipiperidine oxidizes and depletes intracellular reducing pools such as GSH, leading to protein thiol oxidation and oxidative stress, thereby inhibiting DNA single-strand break repair or altering membrane function, ultimately mediating apoptosis signaling and increasing radiosensitivity. 1,1'-(Azodicarbonyl)-dipiperidine can be used in research on pulmonary arterial hypertension, lymphoma, and teratocarcinoma .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
